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Thromb Haemost 1979; 41(02): 407-415
DOI: 10.1055/s-0038-1646789
Original Articles
Schattauer GmbH Stuttgart

Triglyceride Lipase Activity and Human Platelets

Knut Lote
The Department of Internal Medicine, Institute of Clinical Medicine, University of Tromso, 9012 Tromsø, Norway
,
Carol Lowery
The Department of Internal Medicine, Institute of Clinical Medicine, University of Tromso, 9012 Tromsø, Norway
› Author Affiliations
Further Information

Publication History

Received 24 October 1977

Accepted 04 June 1978

Publication Date:
09 July 2018 (online)

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Summary

The activity of triglyceride lipases in human postheparin plasma is significantly higher in platelet rich than platelet poor plasma. This holds for total activity, lipoprotein lipase (LPL) activity, and hepatic triglyceride lipase (H-TGL) activity.

Gel filtration of platelet rich postheparin plasma on Sepharose 2 B will separate platelets from triglyceride lipase activity.

The very small triglyceride lipase activity of isolated platelets is inhibited by 1.0 M NaCl, slightly inhibited by specific antibody to hepatic lipase, and not influenced by specific antibody to lipoprotein lipase.

 

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