Methods Inf Med 1976; 15(04): 216-224
DOI: 10.1055/s-0038-1636672
Original Article
Schattauer GmbH

Clinical Decision Analysis

ENTSCHEIDUNGSTHEORETISCHE ANALYSE KLINISCHER DATEN
Th. R. Taylor
1   (From the Departments of Epidemiology & Health and of Medicine, McGill University, Montreal, Quebec, Canada)
› Author Affiliations
Further Information

Publication History

Publication Date:
20 February 2018 (online)

Attempts have been made for almost two decades to use computers to make clinical diagnoses. Interest in such techniques persists despite little practical success in their application to routine patient care. The explanation of this lack of success is complex and includes (i) lack of understanding of the decisionmaking process itself and (ii) the need for a theoretical framework within which such systems can be developed. A major objective of this paper is to illustrate the contribution that the concepts and techniques associated with Decision Theory can make to both of these problems.

After attempting to analyse the deficiencies of current approaches to computer-assisted diagnosis the paper discusses some of the basic concepts of decision theory. It then illustrates the role of decision theory in studies using different forms of clinical decision analysis.

Finally the paper indicates the relevance of decision analysis to medical education and to the provision of health care.

Seit fast zwei Jahrzehnten wird versucht, Computer bei der klinischen Diagnosestellung einzusetzen. Trotz geringer praktischer Erfolge bei ihrer Anwendung in der routinemäßigen Patientenversorgung hat das Interesse an derartigen Techniken nicht nachgelassen.

Die Erklärung für den Mangel an Erfolg ist schwierig und betrifft 1. mangelndes Verständnis für den Prozeß der Entscheidungsfindung selbst und 2. die Notwendigkeit eines theoretischen Rahmens, in dem solche Systeme entwickelt werden können. Es ist ein wesentliches Ziel dieser Arbeit darzulegen, welchen Beitrag die mit der Entscheidungstheorie verbundenen Begriffe und Techniken bei der Lösung dieser beiden Probleme liefern können.

Im Anschluß an den Versuch, die Schwächen der üblichen Methoden computerunterstützter Diagnostik zu analysieren, werden einige grundlegende Begriffe der Entscheidungstheorie erörtert. Die Rolle der Entscheidungstheorie in Studien, in denen andere Formen klinischer Entscheidungsanalysen benutzt werden, wird sodann dargelegt.

Letztlich wird auf die Bedeutung der Entscheidungsanalyse für die medizinische Ausbildung und die Gesundheitsfürsorge hingewiesen.

 
  • References

  • 1 Aitchison J. Choice against Chance: An Introduction to Statistical Decision Theory. Reading, Massachusetts: Addison-Wesley; 1970
  • 2 Aitchison J, Moore M. F, West S. Α, Taylor T. R. Consistency of Treatment Allocation in Thyrotoxicosis. Quart. J. Med. 42 1973; 573-583.
  • 3 Anderson G, Llerena C, Davidson D, Taylor T. R. Practical Application of Computer-Assisted Decision-Making in an Antenatal Clinic — A Feasibility Study. Meth. Inform. Med 1976; 25: 221-229.
  • 4 Ashley J. S, Pasker P, Beresford J. C. How Much Clinical Investigation. Lancet 1972; 1: 890-892.
  • 5 Barnoon S, Wolfe H. Measuring the Effectiveness of Medical Decisions. Springfield, Illinois: Charles C. Thomas; 1972
  • 6 Betaque N. E, Gorry G. Α.. Automating Judgemental Decision-Making for a Serious Medical Problem. Management Sci. 17 1971; 421-434.
  • 7 Bleich H. L. Computer Evaluation of Acid-Base Disorders. J. clin. Investig. 48 1969; 1689-1696.
  • 8 Bunch W. H, Andrews G. M. Use of Decision Theory in Treatment Selection. Clin. Orthop. 80 1971; 39-53.
  • 9 Collings A. Home or Hospital Care after Myocardial Infarction. Brit. med. J 1974; 1: 559-563.
  • 10 Croft D. J. Is Computerised Diagnosis Possible 7 Comput. biomed. Res. 5 1972; 351-367.
  • 11 Edwards D. N. Do we need a Computer?. Clin. Radiol. 25 1974; 19-25.
  • 12 Elstein A. S, Kagan N, Shulman L. S.. et al. Methods and Theory in the Study of Medical Inquiry. J. med. Educ 1972; 47: 85-92.
  • 13 Emerson P. Α, Teather D, Handley A. J. Application of Decision Theory to the Prevention of Deep Vein Thrombosis following Myocardial Infarction. Quart. J. Med. 43 1974; 389-398.
  • 14 Ginsberg A. S, Offendsend F. L. An Application of Decision Theory to a Medical Diagnosis-Treatment Problem. I.E.E.E. Trans. Syst. Sci. 4 1968; 355-362.
  • 15 Gorky G. Α. Clinical Decision Analysis. Meth. Inform. Med. 12 1973; 45-51.
  • 16 Henschke U. K, Flehincer B. J. Decision Theory in Cancer Therapy. Cancer 20 1967; 1819-1826.
  • 17 Howard R. Α. Decision Analysis: Perspectives on Inference, Decision and Experimentation. Proc. I.E.E.E 1970; 58: 632-643.
  • 18 Lusted L. B. Introduction to Medical Decision-Making. Springfield, Illinois: Charles C. Thomas; 1968
  • 19 Lusted L. B. Decision-Making Studies in Patient Management. New Engl. J. Med 1971; 284: 16-24.
  • 20 Lusted L. B. In the Process of Solution. New Engl. J. Med. 293 1975; 255-256.
  • 21 MacfArlane P. W, Lawrie T. D. V. Automated E.C.G. Interpretation in the National Health Service. Proc. roy. Soc. Lond. (Biol) 1973; 184: 455-471.
  • 22 Mayne J. G, Martin M. J, Taylor W. F. A Health Questionnaire based on Paper- and Pencil Medium, Individualized and Produced by Computer. 3. Usefulness and Acceptability to Physicians. Ann. intern. Med. 76 1972; 923-930.
  • 23 McNeil B. J, Varady P. D, Burrows B. A. et al. Measures of Clinical Efficacy. New Engl. J. Med. 293 1975; 216-221.
  • 24 Moore M. F, Barber J. H, Robinson E. T, Taylor T. R. First-Contact Decisions in General Practice. A Comparison between a Nurse and three General Practitioners. Lancet 1973; 1: 817-819.
  • 25 Moore M. F, Aitchison J, Parker L. S, Taylor T. R. Use of Information in Thyrotoxicosis Treatment Allocation. Meth. Inform. Med. 13 1974; 88-92.
  • 26 Neuhauser D, Lewicki A. M. What do we gain from the Sixth Stool Guaiac?. New Engl. J. Med. 293 1975; 226-220.
  • 27 Raiffa H. Decision Analysis. Reading, Massachusetts: Addison-Wesley; 1968
  • 28 Rockart J. F, McLean E. R, Hershberg P. I. An Automated Medical History System. Experience of the Lahcy Clinic Foundation with Computer-Processed Medical Histories. Arch, intern. Med. 132 1973; 348-358.
  • 29 Sanazaro P. J. Medical Audit: Experience in the U.S.A. Brit, med. J 1974; 1: 348-358.
  • 30 Schwartz W. B, Gorry G. Α, Kassirer J. P. et al. Decision Analysis and Clinical Judgement. Amer. J. Med 1973; 55: 459-472.
  • 31 Shortliffe E. H, Axline S. G, Buchanan B. G. et al. Artificial Intelligence Program to advise Physicians Regarding Antimicrobial Therapy. Comput. biomcd. Res 6 1973; 544-560.
  • 32 Slack W. V, Van Cuba L. J, Greist J. H. Computers and Doctors: Use and Consequences. Comput. biomed. Res. 3 1970; 521-527.
  • 33 Swets J. A. (Edit.) Signal Detection and Recognition by Human Observers. New York: John Wiley; 1964
  • 34 Taylor T. R. The Principles of Medical Computing. Oxford, Blackwell Scientific Publications Ltd; 1967
  • 35 Taylor T. R. Computer-Guided Diagnosis. J. roy. Coll. Physn. Lond. 4 1970; 188-195.
  • 36 Taylor T. R. Computer Assisted Instruction in Medical Education. Progr. Learning 9 1972; 272-282.
  • 37 Taylor T. R, Shields S, Black R. Study of Cost-Conscious Computer-Assisted Diagnosis in Thyroid Disease. Lancet 1972; 2: 79-83.
  • 38 Taylor T. R. The Quality of Health Care and the Assessment of Clinical Competence. Scott, med. J. 20 1974; 45-47.
  • 39 Taylor T. R. Computer-Assisted Learning of Clinical Decision-Making. In Hooper R. (Edit.) Computer-Assisted Lear- ning in the United Kingdom. Council of Educational Technology; London: 1975
  • 40 Taylor T. R, Aitchison J, Parker L. S, Moore M. F. Individual Differences in Selecting Patients for Regular Haemodialysis. Brit. med. J 1975; 2: 380-381.
  • 41 Warner H. R, Toronto A. F, Veasey L. G. et al. A Mathematical Approach to Medical Diagnosis. J. Amer. med. Ass. 177 1961; 177-183.
  • 42 Wortman P. M. Medical Diagnosis: An Information-Processing Approach. Comput. biomed. Res. 5 1972; 315-328.
  • 43 Wooton I. D. P. Computer Science in the Biochemistry Laboratory. Brit. med. Bull. 24 1968; 219-223.