Semin Respir Crit Care Med 2015; 36(06): 851-858
DOI: 10.1055/s-0035-1564872
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

To Trach or Not to Trach: Uncertainty in the Care of the Chronically Critically Ill

Thomas Bice
1   University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
,
Judith E. Nelson
2   Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York
,
Shannon S. Carson
1   University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
› Author Affiliations
Further Information

Publication History

Publication Date:
23 November 2015 (online)

Abstract

The number of chronically critically ill patients requiring prolonged mechanical ventilation and receiving a tracheostomy is steadily increasing. Early tracheostomy in patients requiring prolonged mechanical ventilation has been proposed to decrease duration of mechanical ventilation and intensive care unit stay, reduce mortality, and improve patient comfort. However, these benefits have been difficult to demonstrate in clinical trials. So how does one determine the appropriate timing for tracheostomy placement in your patient? Here we review the potential benefits and consequences of tracheostomy, the available evidence for tracheostomy timing, communication surrounding the tracheostomy decision, and a patient-centered approach to tracheostomy. Patients requiring > 10 days of mechanical ventilation who are expected to survive their hospitalization likely benefit from tracheostomy, but protocols involving routine early tracheostomy placement do not improve patient outcomes. However, patients with neurologic injury, provided they have a good prognosis for meaningful recovery, may benefit from early tracheostomy. In chronically critically ill patients with poor prognosis, tracheostomy is unlikely to provide benefit and should only be pursued if it is consistent with the patient's values, goals, and preferences. In this setting, communication with patients and surrogates regarding tracheostomy and prognosis becomes paramount. For the foreseeable future, decisions surrounding tracheostomy will remain relevant and challenging.

 
  • References

  • 1 Zilberberg MD, Luippold RS, Sulsky S, Shorr AF. Prolonged acute mechanical ventilation, hospital resource utilization, and mortality in the United States. Crit Care Med 2008; 36 (3) 724-730
  • 2 Cox CE, Martinu T, Sathy SJ , et al. Expectations and outcomes of prolonged mechanical ventilation. Crit Care Med 2009; 37 (11) 2888-2894 , quiz 2904
  • 3 Unroe M, Kahn JM, Carson SS , et al. One-year trajectories of care and resource utilization for recipients of prolonged mechanical ventilation: a cohort study. Ann Intern Med 2010; 153 (3) 167-175
  • 4 Carson SS, Kahn JM, Hough CL , et al; ProVent Investigators. A multicenter mortality prediction model for patients receiving prolonged mechanical ventilation. Crit Care Med 2012; 40 (4) 1171-1176
  • 5 Cox CE, Carson SS, Lindquist JH, Olsen MK, Govert JA, Chelluri L ; Quality of Life After Mechanical Ventilation in the Aged (QOL-MV) Investigators. Differences in one-year health outcomes and resource utilization by definition of prolonged mechanical ventilation: a prospective cohort study. Crit Care 2007; 11 (1) R9
  • 6 Cox CE, Carson SS, Holmes GM, Howard A, Carey TS. Increase in tracheostomy for prolonged mechanical ventilation in North Carolina, 1993–2002. Crit Care Med 2004; 32 (11) 2219-2226
  • 7 Mehta AB, Syeda SN, Bajpayee L, Cooke CR, Walkey AJ, Wiener RS. Trends in tracheostomy for mechanically ventilated patients in the United States, 1993–2012. Am J Respir Crit Care Med 2015; 192 (4) 446-454
  • 8 Calfee CS, Delucchi K, Parsons PE, Thompson BT, Ware LB, Matthay MA ; NHLBI ARDS Network. Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials. Lancet Respir Med 2014; 2 (8) 611-620
  • 9 Heffner JE. The role of tracheotomy in weaning. Chest 2001; 120 (6, Suppl): 477S-481S
  • 10 Mallick A, Bodenham AR. Tracheostomy in critically ill patients. Eur J Anaesthesiol 2010; 27 (8) 676-682
  • 11 Blot F, Similowski T, Trouillet JL , et al. Early tracheotomy versus prolonged endotracheal intubation in unselected severely ill ICU patients. Intensive Care Med 2008; 34 (10) 1779-1787
  • 12 Andriolo BN, Andriolo RB, Saconato H, Atallah AN, Valente O. Early versus late tracheostomy for critically ill patients. Cochrane Database Syst Rev 2015; 1: CD007271
  • 13 Barquist ES, Amortegui J, Hallal A , et al. Tracheostomy in ventilator dependent trauma patients: a prospective, randomized intention-to-treat study. J Trauma 2006; 60 (1) 91-97
  • 14 Bösel J, Schiller P, Hook Y , et al. Stroke-related Early Tracheostomy versus Prolonged Orotracheal Intubation in Neurocritical Care Trial (SETPOINT): a randomized pilot trial. Stroke 2013; 44 (1) 21-28
  • 15 Bouderka MA, Fakhir B, Bouaggad A, Hmamouchi B, Hamoudi D, Harti A. Early tracheostomy versus prolonged endotracheal intubation in severe head injury. J Trauma 2004; 57 (2) 251-254
  • 16 Dunham CM, LaMonica C. Prolonged tracheal intubation in the trauma patient. J Trauma 1984; 24 (2) 120-124
  • 17 El-Naggar M, Sadagopan S, Levine H, Kantor H, Collins VJ. Factors influencing choice between tracheostomy and prolonged translaryngeal intubation in acute respiratory failure: a prospective study. Anesth Analg 1976; 55 (2) 195-201
  • 18 Griffiths J, Barber VS, Morgan L, Young JD. Systematic review and meta-analysis of studies of the timing of tracheostomy in adult patients undergoing artificial ventilation. BMJ 2005; 330 (7502) 1243
  • 19 Huang H, Li Y, Ariani F, Chen X, Lin J. Timing of tracheostomy in critically ill patients: a meta-analysis. PLoS ONE 2014; 9 (3) e92981
  • 20 Koch T, Hecker B, Hecker A , et al. Early tracheostomy decreases ventilation time but has no impact on mortality of intensive care patients: a randomized study. Langenbecks Arch Surg 2012; 397 (6) 1001-1008
  • 21 Liu CC, Livingstone D, Dixon E, Dort JC. Early versus late tracheostomy: a systematic review and meta-analysis. Otolaryngol Head Neck Surg 2015; 152 (2) 219-227
  • 22 Meng L, Wang CM, Li JX, Zhang J. Early versus late tracheostomy in critically ill patients: a systematic review and meta-analysis. Clin Respir J 2015;
  • 23 Rodriguez JL, Steinberg SM, Luchetti FA, Gibbons KJ, Taheri PA, Flint LM. Early tracheostomy for primary airway management in the surgical critical care setting. Surgery 1990; 108 (4) 655-659
  • 24 Rumbak MJ, Newton M, Truncale T, Schwartz SW, Adams JW, Hazard PB. A prospective, randomized, study comparing early percutaneous dilational tracheotomy to prolonged translaryngeal intubation (delayed tracheotomy) in critically ill medical patients. Crit Care Med 2004; 32 (8) 1689-1694
  • 25 Saffle JR, Morris SE, Edelman L. Early tracheostomy does not improve outcome in burn patients. J Burn Care Rehabil 2002; 23 (6) 431-438
  • 26 Siempos II, Ntaidou TK, Filippidis FT, Choi AMK. Effect of early versus late or no tracheostomy on mortality and pneumonia of critically ill patients receiving mechanical ventilation: a systematic review and meta-analysis. Lancet Respir Med 2015; 3 (2) 150-158
  • 27 Sugerman HJ, Wolfe L, Pasquale MD , et al. Multicenter, randomized, prospective trial of early tracheostomy. J Trauma 1997; 43 (5) 741-747
  • 28 Terragni PP, Antonelli M, Fumagalli R , et al. Early vs late tracheotomy for prevention of pneumonia in mechanically ventilated adult ICU patients: a randomized controlled trial. JAMA 2010; 303 (15) 1483-1489
  • 29 Trouillet JL, Luyt CE, Guiguet M , et al. Early percutaneous tracheotomy versus prolonged intubation of mechanically ventilated patients after cardiac surgery: a randomized trial. Ann Intern Med 2011; 154 (6) 373-383
  • 30 Wang F, Wu Y, Bo L , et al. The timing of tracheotomy in critically ill patients undergoing mechanical ventilation: a systematic review and meta-analysis of randomized controlled trials. Chest 2011; 140 (6) 1456-1465
  • 31 Young D, Harrison DA, Cuthbertson BH, Rowan K ; TracMan Collaborators. Effect of early vs late tracheostomy placement on survival in patients receiving mechanical ventilation: the TracMan randomized trial. JAMA 2013; 309 (20) 2121-2129
  • 32 Zheng Y, Sui F, Chen XK , et al. Early versus late percutaneous dilational tracheostomy in critically ill patients anticipated requiring prolonged mechanical ventilation. Chin Med J (Engl) 2012; 125 (11) 1925-1930
  • 33 Dunham CM, Ransom KJ. Assessment of early tracheostomy in trauma patients: a systematic review and meta-analysis. Am Surg 2006; 72 (3) 276-281
  • 34 Siempos II, Ntaidou TK, Filippidis FT, Choi AM. Effect of early versus late or no tracheostomy on mortality and pneumonia of critically ill patients receiving mechanical ventilation: a systematic review and meta-analysis. Lancet Respir Med 2015; 3 (2) 150-158
  • 35 Szakmany T, Russell P, Wilkes AR, Hall JE. Effect of early tracheostomy on resource utilization and clinical outcomes in critically ill patients: meta-analysis of randomized controlled trials. Br J Anaesth 2015; 114 (3) 396-405
  • 36 Rabinstein AA, Wijdicks EF. Outcome of survivors of acute stroke who require prolonged ventilatory assistance and tracheostomy. Cerebrovasc Dis 2004; 18 (4) 325-331
  • 37 Pinheiro BdoV, Tostes RdeO, Brum CI, Carvalho EV, Pinto SP, Oliveira JC. Early versus late tracheostomy in patients with acute severe brain injury. J Bras Pneumol 2010; 36 (1) 84-91
  • 38 Qureshi AI, Suarez JI, Parekh PD, Bhardwaj A. Prediction and timing of tracheostomy in patients with infratentorial lesions requiring mechanical ventilatory support. Crit Care Med 2000; 28 (5) 1383-1387
  • 39 van der Lely AJ, Veelo DP, Dongelmans DA, Korevaar JC, Vroom MB, Schultz MJ. Time to wean after tracheotomy differs among subgroups of critically ill patients: retrospective analysis in a mixed medical/surgical intensive care unit. Respir Care 2006; 51 (12) 1408-1415
  • 40 Bronchard R, Albaladejo P, Brezac G , et al. Early onset pneumonia: risk factors and consequences in head trauma patients. Anesthesiology 2004; 100 (2) 234-239
  • 41 Melsen WG, Rovers MM, Groenwold RH , et al. Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studies. Lancet Infect Dis 2013; 13 (8) 665-671
  • 42 Yang CC, Shih NC, Chang WC, Huang SK, Chien CW. Long-term medical utilization following ventilator-associated pneumonia in acute stroke and traumatic brain injury patients: a case-control study. BMC Health Serv Res 2011; 11: 289
  • 43 Freeman BD, Morris PE. Tracheostomy practice in adults with acute respiratory failure. Crit Care Med 2012; 40 (10) 2890-2896
  • 44 Nelson JE, Kinjo K, Meier DE, Ahmad K, Morrison RS. When critical illness becomes chronic: informational needs of patients and families. J Crit Care 2005; 20 (1) 79-89
  • 45 Nelson JE, Mercado AF, Camhi SL , et al. Communication about chronic critical illness. Arch Intern Med 2007; 167 (22) 2509-2515
  • 46 Nelson JE, Meier DE, Litke A, Natale DA, Siegel RE, Morrison RS. The symptom burden of chronic critical illness. Crit Care Med 2004; 32 (7) 1527-1534
  • 47 Nelson JE, Tandon N, Mercado AF, Camhi SL, Ely EW, Morrison RS. Brain dysfunction: another burden for the chronically critically ill. Arch Intern Med 2006; 166 (18) 1993-1999
  • 48 Carson SS, Bach PB, Brzozowski L, Leff A. Outcomes after long-term acute care. An analysis of 133 mechanically ventilated patients. Am J Respir Crit Care Med 1999; 159 (5 Pt 1): 1568-1573
  • 49 Hope AA, Morrison RS, Du Q, Wallenstein S, Nelson JE. Risk factors for long-term brain dysfunction after chronic critical illness. Ann Am Thorac Soc 2013; 10 (4) 315-323
  • 50 Kahn JM, Benson NM, Appleby D, Carson SS, Iwashyna TJ. Long-term acute care hospital utilization after critical illness. JAMA 2010; 303 (22) 2253-2259
  • 51 Kahn JM, Le T, Angus DC , et al; ProVent Study Group Investigators. The epidemiology of chronic critical illness in the United States*. Crit Care Med 2015; 43 (2) 282-287
  • 52 Curtis JR, Engelberg RA, Wenrich MD, Shannon SE, Treece PD, Rubenfeld GD. Missed opportunities during family conferences about end-of-life care in the intensive care unit. Am J Respir Crit Care Med 2005; 171 (8) 844-849
  • 53 Azoulay E, Chevret S, Leleu G , et al. Half the families of intensive care unit patients experience inadequate communication with physicians. Crit Care Med 2000; 28 (8) 3044-3049
  • 54 Nelson JE, Angus DC, Weissfeld LA , et al; Critical Care Peer Workgroup of the Promoting Excellence in End-of-Life Care Project. End-of-life care for the critically ill: A national intensive care unit survey. Crit Care Med 2006; 34 (10) 2547-2553
  • 55 Needham DM, Davidson J, Cohen H , et al. Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders' conference. Crit Care Med 2012; 40 (2) 502-509
  • 56 Azoulay E, Pochard F, Kentish-Barnes N , et al; FAMIREA Study Group. Risk of post-traumatic stress symptoms in family members of intensive care unit patients. Am J Respir Crit Care Med 2005; 171 (9) 987-994
  • 57 Anderson WG, Arnold RM, Angus DC, Bryce CL. Posttraumatic stress and complicated grief in family members of patients in the intensive care unit. J Gen Intern Med 2008; 23 (11) 1871-1876
  • 58 Kentish-Barnes N, Chaize M, Seegers V , et al. Complicated grief after death of a relative in the intensive care unit. Eur Respir J 2015; 45 (5) 1341-1352
  • 59 Davidson JE, Jones C, Bienvenu OJ. Family response to critical illness: postintensive care syndrome-family. Crit Care Med 2012; 40 (2) 618-624
  • 60 Evans LR, Boyd EA, Malvar G , et al. Surrogate decision-makers' perspectives on discussing prognosis in the face of uncertainty. Am J Respir Crit Care Med 2009; 179 (1) 48-53
  • 61 Apatira L, Boyd EA, Malvar G , et al. Hope, truth, and preparing for death: perspectives of surrogate decision makers. Ann Intern Med 2008; 149 (12) 861-868
  • 62 Jackson VA, Jacobsen J, Greer JA, Pirl WF, Temel JS, Back AL. The cultivation of prognostic awareness through the provision of early palliative care in the ambulatory setting: a communication guide. J Palliat Med 2013; 16 (8) 894-900
  • 63 Nelson JE, Cox CE, Hope AA, Carson SS. Chronic critical illness. Am J Respir Crit Care Med 2010; 182 (4) 446-454
  • 64 Carson SS, Garrett J, Hanson LC , et al. A prognostic model for one-year mortality in patients requiring prolonged mechanical ventilation. Crit Care Med 2008; 36 (7) 2061-2069
  • 65 Hough CL, Caldwell ES, Cox CE , et al; ProVent Investigators and the National Heart Lung and Blood Institute's Acute Respiratory Distress Syndrome Network. Development and validation of a mortality prediction model for patients receiving 14 days of mechanical ventilation. Crit Care Med 2015;
  • 66 Back A, Arnold R, Tulsky J. Mastering Communication with Seriously Ill Patients: Balancing Honesty with Empathy and Hope. New York, NY: Cambridge University Press; 2009
  • 67 Curtis JR, White DB. Practical guidance for evidence-based ICU family conferences. Chest 2008; 134 (4) 835-843
  • 68 Carson SS, Vu M, Danis M , et al. Development and validation of a printed information brochure for families of chronically critically ill patients. Crit Care Med 2012; 40 (1) 73-78
  • 69 McDonagh JR, Elliott TB, Engelberg RA , et al. Family satisfaction with family conferences about end-of-life care in the intensive care unit: increased proportion of family speech is associated with increased satisfaction. Crit Care Med 2004; 32 (7) 1484-1488
  • 70 Pollak KI, Arnold RM, Jeffreys AS , et al. Oncologist communication about emotion during visits with patients with advanced cancer. J Clin Oncol 2007; 25 (36) 5748-5752
  • 71 Stapleton RD, Engelberg RA, Wenrich MD, Goss CH, Curtis JR. Clinician statements and family satisfaction with family conferences in the intensive care unit. Crit Care Med 2006; 34 (6) 1679-1685
  • 72 Dartmouth Atlas of Health Care Available at: http://www.dartmouthatlas.org/keyissues/issue.aspx?con=2938 . Accessed 2015
  • 73 White DB, Braddock III CH, Bereknyei S, Curtis JR. Toward shared decision making at the end of life in intensive care units: opportunities for improvement. Arch Intern Med 2007; 167 (5) 461-467
  • 74 Camhi SL, Mercado AF, Morrison RS , et al. Deciding in the dark: advance directives and continuation of treatment in chronic critical illness. Crit Care Med 2009; 37 (3) 919-925
  • 75 Camhi S. Communication about chronic critical illness. Proc Am Thorac Soc 2005; 2: A594
  • 76 Fried TR, Bradley EH, Towle VR, Allore H. Understanding the treatment preferences of seriously ill patients. N Engl J Med 2002; 346 (14) 1061-1066
  • 77 Fried TR, Van Ness PH, Byers AL, Towle VR, O'Leary JR, Dubin JA. Changes in preferences for life-sustaining treatment among older persons with advanced illness. J Gen Intern Med 2007; 22 (4) 495-501
  • 78 Krimshtein NS, Luhrs CA, Puntillo KA , et al. Training nurses for interdisciplinary communication with families in the intensive care unit: an intervention. J Palliat Med 2011; 14 (12) 1325-1332
  • 79 Nelson JE, Mulkerin CM, Adams LL, Pronovost PJ. Improving comfort and communication in the ICU: a practical new tool for palliative care performance measurement and feedback. Qual Saf Health Care 2006; 15 (4) 264-271
  • 80 Morrison RS, Augustin R, Souvanna P, Meier DE. America's care of serious illness: a state-by-state report card on access to palliative care in our nation's hospitals. J Palliat Med 2011; 14 (10) 1094-1096
  • 81 Chronic Critical Illness. 2010 . Available at: http://www.myicucare.org/Adult-Support/Pages/Chronic-Critical-Illness.aspx . Accessed April 27, 2015