Clin Colon Rectal Surg 2014; 27(03): 116-120
DOI: 10.1055/s-0034-1387800
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Novel Treatment Options for Fecal Incontinence

Adam Barker
1   Department of Colon and Rectal Surgery, Presbyterian Hospital, Dallas, Texas
,
Jefferson Hurley
1   Department of Colon and Rectal Surgery, Presbyterian Hospital, Dallas, Texas
› Author Affiliations
Further Information

Publication History

Publication Date:
24 September 2014 (online)

Abstract

Fecal incontinence (FI) is a devastating condition affecting a substantial portion of the population. The etiologies of FI are wide ranging, as are the treatment options. When conservative measures fail, often surgical intervention is required. As in any area where a wide range of treatment options exist, there is no one perfect solution. Fortunately, novel treatment options for FI are becoming available, namely, posterior tibial nerve stimulation, magnetic anal sphincter, stem cell transplant, pyloric transplantation, and acupuncture.

 
  • References

  • 1 Potter J. Bowel care in older people. Clin Med 2003; 3 (1) 48-51
  • 2 Norton C, Cody JD, Hosker G. Biofeedback and/or sphincter exercises for the treatment of faecal incontinence in adults. Cochrane Database Syst Rev 2006; (3) CD002111
  • 3 Rogers RG, Abed H, Fenner DE. Current diagnosis and treatment algorithms for anal incontinence. BJU Int 2006; 98 (Suppl. 01) 97-106 , discussion 107–109
  • 4 MacArthur C, Bick DE, Keighley MR. Faecal incontinence after childbirth. Br J Obstet Gynaecol 1997; 104 (1) 46-50
  • 5 Bellicini N, Molloy PJ, Caushaj P, Kozlowski P. Fecal incontinence: a review. Dig Dis Sci 2008; 53 (1) 41-46
  • 6 Rao SS. Pathophysiology of adult fecal incontinence. Gastroenterology 2004; 126 (1) (Suppl. 01) S14-S22
  • 7 Osterberg A, Edebol Eeg-Olofsson K, Hålldén M, Graf W. Randomized clinical trial comparing conservative and surgical treatment of neurogenic faecal incontinence. Br J Surg 2004; 91 (9) 1131-1137
  • 8 Madoff RD. Surgical treatment options for fecal incontinence. Gastroenterology 2004; 126 (1) (Suppl. 01) S48-S54
  • 9 Melzack R, Wall PD. Pain mechanisms: a new theory. Science 1965; 150 (3699) 971-979
  • 10 Tanagho EA, Schmidt RA. Electrical stimulation in the clinical management of the neurogenic bladder. J Urol 1988; 140 (6) 1331-1339
  • 11 Gourcerol G, Vitton V, Leroi AM, Michot F, Abysique A, Bouvier M. How sacral nerve stimulation works in patients with faecal incontinence. Colorectal Dis 2011; 13 (8) e203-e211
  • 12 Jarrett ME, Mowatt G, Glazener CM , et al. Systematic review of sacral nerve stimulation for faecal incontinence and constipation. Br J Surg 2004; 91 (12) 1559-1569
  • 13 Peters KM, Macdiarmid SA, Wooldridge LS , et al. Randomized trial of percutaneous tibial nerve stimulation versus extended-release tolterodine: results from the overactive bladder innovative therapy trial. J Urol 2009; 182 (3) 1055-1061
  • 14 Nakamura M, Sakurai T, Tsujimoto Y, Tada Y. Transcutaneous electrical stimulation for the control of frequency and urge incontinence [in Japanese]. Hinyokika Kiyo 1983; 29 (9) 1053-1059
  • 15 Findlay JM, Maxwell-Armstrong C. Posterior tibial nerve stimulation and faecal incontinence: a review. Int J Colorectal Dis 2011; 26 (3) 265-273
  • 16 Shafik A, Ahmed I, El-Sibai O, Mostafa RM. Percutaneous peripheral neuromodulation in the treatment of fecal incontinence. Eur Surg Res 2003; 35 (2) 103-107
  • 17 Queralto M, Portier G, Cabarrot PH , et al. Preliminary results of peripheral transcutaneous neuromodulation in the treatment of idiopathic fecal incontinence. Int J Colorectal Dis 2006; 21 (7) 670-672
  • 18 Govaert B, Pares D, Delgado-Aros S, La Torre F, Van Gemert WG, Baeten CG. A prospective multicentre study to investigate percutaneous tibial nerve stimulation for the treatment of faecal incontinence. Colorectal Dis 2010; 12 (12) 1236-1241
  • 19 de la Portilla F, Rada R, Vega J, González CA, Cisneros N, Maldonado VH. Evaluation of the use of posterior tibial nerve stimulation for the treatment of fecal incontinence: preliminary results of a prospective study. Dis Colon Rectum 2009; 52 (8) 1427-1433
  • 20 Boyle DJ, Prosser K, Allison ME, Williams NS, Chan CL. Percutaneous tibial nerve stimulation for the treatment of urge fecal incontinence. Dis Colon Rectum 2010; 53 (4) 432-437
  • 21 Hotouras A, Thaha MA, Boyle DJ , et al. Short-term outcome following percutaneous tibial nerve stimulation for faecal incontinence: a single-centre prospective study. Colorectal Dis 2012; 14 (9) 1101-1105
  • 22 Leroi AM, Siproudhis L, Etienney I , et al. Transcutaneous electrical tibial nerve stimulation in the treatment of fecal incontinence: a randomized trial (CONSORT 1a). Am J Gastroenterol 2012; 107 (12) 1888-1896
  • 23 George AT, Kalmar K, Sala S , et al. Randomized controlled trial of percutaneous versus transcutaneous posterior tibial nerve stimulation in faecal incontinence. Br J Surg 2013; 100 (3) 330-338
  • 24 Thomas GP, Dudding TC, Bradshaw E, Nicholls RJ, Vaizey CJ. A pilot study to compare daily with twice weekly transcutaneous posterior tibial nerve stimulation for faecal incontinence. Colorectal Dis 2013; 15 (12) 1504-1509
  • 25 Thomas GP, Dudding TC, Nicholls RJ, Vaizey CJ. Bilateral transcutaneous posterior tibial nerve stimulation for the treatment of fecal incontinence. Dis Colon Rectum 2013; 56 (9) 1075-1079
  • 26 Bonavina L, Saino GI, Bona D , et al. Magnetic augmentation of the lower esophageal sphincter: results of a feasibility clinical trial. J Gastrointest Surg 2008; 12 (12) 2133-2140
  • 27 Ganz RA, Gostout CJ, Grudem J, Swanson W, Berg T, DeMeester TR. Use of a magnetic sphincter for the treatment of GERD: a feasibility study. Gastrointest Endosc 2008; 67 (2) 287-294
  • 28 Lehur PA, McNevin S, Buntzen S, Mellgren AF, Laurberg S, Madoff RD. Magnetic anal sphincter augmentation for the treatment of fecal incontinence: a preliminary report from a feasibility study. Dis Colon Rectum 2010; 53 (12) 1604-1610
  • 29 Wong MT, Meurette G, Stangherlin P, Lehur PA. The magnetic anal sphincter versus the artificial bowel sphincter: a comparison of 2 treatments for fecal incontinence. Dis Colon Rectum 2011; 54 (7) 773-779
  • 30 Wong MT, Meurette G, Wyart V, Lehur PA. Does the magnetic anal sphincter device compare favourably with sacral nerve stimulation in the management of faecal incontinence?. Colorectal Dis 2012; 14 (6) e323-e329
  • 31 Barussaud ML, Mantoo S, Wyart V, Meurette G, Lehur PA. The magnetic anal sphincter in faecal incontinence: is initial success sustained over time?. Colorectal Dis 2013; 15 (12) 1499-1503
  • 32 Pathi SD, Acevedo JF, Keller PW , et al. Recovery of the injured external anal sphincter after injection of local or intravenous mesenchymal stem cells. Obstet Gynecol 2012; 119 (1) 134-144
  • 33 White AB, Keller PW, Acevedo JF, Word RA, Wai CY. Effect of myogenic stem cells on contractile properties of the repaired and unrepaired transected external anal sphincter in an animal model. Obstet Gynecol 2010; 115 (4) 815-823
  • 34 Frudinger A, Kölle D, Schwaiger W, Pfeifer J, Paede J, Halligan S. Muscle-derived cell injection to treat anal incontinence due to obstetric trauma: pilot study with 1.  year follow-up. Gut 2010; 59 (1) 55-61
  • 35 Goldsmith HS, Chandra A. Pyloric valve transposition as substitute for a colostomy in humans: a preliminary report. Am J Surg 2011; 202 (4) 409-416
  • 36 Chandra A, Kumar A, Noushif M , et al. Perineal antropylorus transposition for end-stage fecal incontinence in humans: initial outcomes. Dis Colon Rectum 2013; 56 (3) 360-366
  • 37 Fleshman JW. Should we, not could we? A commentary on “Pyloric valve transposition as substitute for a colostomy in humans: a preliminary report”. Am J Surg 2011; 202 (4) 417-418
  • 38 Scaglia M, Delaini G, Destefano I, Hultén L. Fecal incontinence treated with acupuncture—a pilot study. Auton Neurosci 2009; 145 (1-2) 89-92