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Semin Musculoskelet Radiol 2013; 17(01): 069-073
DOI: 10.1055/s-0033-1333939
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Rheumatoid Arthritis

Andrew J. Grainger
1   Department of Radiology, Leeds Teaching Hospitals, Chapel Allerton Hospital, Leeds, United Kingdom
2   Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals, Chapel Allerton Hospital, Leeds, United Kingdom
,
Emma L. Rowbotham
3   Department of Radiology, Royal United Hospital, Bath, United Kingdom
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Publikationsdatum:
13. März 2013 (online)

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Abstract

Since the advent of disease-modifying antirheumatic drugs for the treatment of rheumatoid arthritis, there has been an increasing emphasis on the early diagnosis and monitoring of this condition. This has led to the greater involvement of advanced imaging techniques such as ultrasound and MRI. Ultrasound appearances of common findings in rheumatoid arthritis are discussed in this review. Comparison of ultrasound in terms of sensitivity and specificity with other imaging modalities and with clinical examination is also made. Quantification is also discussed as a tool to allow assessment of response to drug therapy, an area that is likely to progress further as techniques become increasingly reproducible. Finally, as ultrasound techniques continue to develop, its involvement in the management of patients with rheumatoid arthritis is increasing. New techniques such as fusion imaging and sonoelastography, while at present still largely research-based entities, may offer increasingly improved diagnostic benefits in the field of inflammatory arthropathy.

Keywords

ultrasound - rheumatoid arthritis - synovitis
 

  • References

  • 1 Wakefield RJ, Balint PV, Szkudlarek M , et al; OMERACT 7 Special Interest Group. Musculoskeletal ultrasound including definitions for ultrasonographic pathology. J Rheumatol 2005; 32 (12) 2485-2487
    PubMedGoogle Scholar
  • 2 Combe B, Landewe R, Lukas C , et al. EULAR recommendations for the management of early arthritis: report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 2007; 66 (1) 34-45
    CrossrefPubMedGoogle Scholar
  • 3 Szkudlarek M, Narvestad E, Klarlund M, Court-Payen M, Thomsen HS, Østergaard M. Ultrasonography of the metatarsophalangeal joints in rheumatoid arthritis: comparison with magnetic resonance imaging, conventional radiography, and clinical examination. Arthritis Rheum 2004; 50 (7) 2103-2112
    CrossrefPubMedGoogle Scholar
  • 4 Finzel S, Ohrndorf S, Englbrecht M , et al. A detailed comparative study of high-resolution ultrasound and micro-computed tomography for detection of arthritic bone erosions. Arthritis Rheum 2011; 63 (5) 1231-1236
    CrossrefPubMedGoogle Scholar
  • 5 Boutry N, Lardé A, Demondion X, Cortet B, Cotten H, Cotten A. Metacarpophalangeal joints at US in asymptomatic volunteers and cadaveric specimens. Radiology 2004; 232 (3) 716-724
    CrossrefPubMedGoogle Scholar
  • 6 Möller B, Bonel H, Rotzetter M, Villiger PM, Ziswiler HR. Measuring finger joint cartilage by ultrasound as a promising alternative to conventional radiograph imaging. Arthritis Rheum 2009; 61 (4) 435-441
    CrossrefPubMedGoogle Scholar
  • 7 Koski JM, Saarakkala S, Helle M, Hakulinen U, Heikkinen JO, Hermunen H. Power Doppler ultrasonography and synovitis: correlating ultrasound imaging with histopathological findings and evaluating the performance of ultrasound equipment. Ann Rheum Dis 2006; 65 (12) 1590-1595
    CrossrefPubMedGoogle Scholar
  • 8 Torp-Pedersen ST, Terslev L. Settings and artefacts relevant in colour/power Doppler ultrasound in rheumatology. Ann Rheum Dis 2008; 67 (2) 143-149
    CrossrefPubMedGoogle Scholar
  • 9 Wakefield RJ, Gibbon WW, Conaghan PG , et al. The value of sonography in the detection of bone erosions in patients with rheumatoid arthritis: a comparison with conventional radiography. Arthritis Rheum 2000; 43 (12) 2762-2770
    CrossrefPubMedGoogle Scholar
  • 10 Weidekamm C, Köller M, Weber M, Kainberger F. Diagnostic value of high-resolution B-mode and Doppler sonography for imaging of hand and finger joints in rheumatoid arthritis. Arthritis Rheum 2003; 48 (2) 325-333
    CrossrefPubMedGoogle Scholar
  • 11 Rowbotham EL, Grainger AJ. Rheumatoid arthritis: ultrasound versus MRI. AJR Am J Roentgenol 2011; 197 (3) 541-546
    CrossrefPubMedGoogle Scholar
  • 12 McQueen FM, Benton N, Perry D , et al. Bone edema scored on magnetic resonance imaging scans of the dominant carpus at presentation predicts radiographic joint damage of the hands and feet six years later in patients with rheumatoid arthritis. Arthritis Rheum 2003; 48 (7) 1814-1827
    CrossrefPubMedGoogle Scholar
  • 13 Backhaus M, Kamradt T, Sandrock D , et al. Arthritis of the finger joints: a comprehensive approach comparing conventional radiography, scintigraphy, ultrasound, and contrast-enhanced magnetic resonance imaging. Arthritis Rheum 1999; 42 (6) 1232-1245
    CrossrefPubMedGoogle Scholar
  • 14 Koski JM, Anttila P, Hämäläinen M, Isomäki H. Hip joint ultrasonography: correlation with intra-articular effusion and synovitis. Br J Rheumatol 1990; 29 (3) 189-192
    CrossrefPubMedGoogle Scholar
  • 15 Filippucci E, Iagnocco A, Salaffi F, Cerioni A, Valesini G, Grassi W. Power Doppler sonography monitoring of synovial perfusion at the wrist joints in patients with rheumatoid arthritis treated with adalimumab. Ann Rheum Dis 2006; 65 (11) 1433-1437
    CrossrefPubMedGoogle Scholar
  • 16 Ribbens C, André B, Marcelis S , et al. Rheumatoid hand joint synovitis: gray-scale and power Doppler US quantifications following anti-tumor necrosis factor-alpha treatment: pilot study. Radiology 2003; 229 (2) 562-569
    CrossrefPubMedGoogle Scholar
  • 17 Strunk J, Strube K, Müller-Ladner U, Lange U. Three dimensional power Doppler ultrasonography confirms early reduction of synovial perfusion after intra-articular steroid injection. Ann Rheum Dis 2006; 65 (3) 411-412
    CrossrefPubMedGoogle Scholar
  • 18 Takamoto S, Saeki S, Yabumoto Y , et al. Spontaneous fractures of long bones associated with joint contractures in bedridden elderly inpatients: clinical features and outcome. J Am Geriatr Soc 2005; 53 (8) 1439-1441
    CrossrefPubMedGoogle Scholar
  • 19 Teh J, Stevens K, Williamson L, Leung J, McNally EG. Power Doppler ultrasound of rheumatoid synovitis: quantification of therapeutic response. Br J Radiol 2003; 76 (912) 875-879
    CrossrefPubMedGoogle Scholar
  • 20 Walther M, Harms H, Krenn V, Radke S, Faehndrich TP, Gohlke F. Correlation of power Doppler sonography with vascularity of the synovial tissue of the knee joint in patients with osteoarthritis and rheumatoid arthritis. Arthritis Rheum 2001; 44 (2) 331-338
    CrossrefPubMedGoogle Scholar
  • 21 Walther M, Harms H, Krenn V, Radke S, Kirschner S, Gohlke F. Synovial tissue of the hip at power Doppler US: correlation between vascularity and power Doppler US signal. Radiology 2002; 225 (1) 225-231
    CrossrefPubMedGoogle Scholar
  • 22 Huang J, Stewart N, Crabbe J , et al. A 1-year follow-up study of dynamic magnetic resonance imaging in early rheumatoid arthritis reveals synovitis to be increased in shared epitope-positive patients and predictive of erosions at 1 year. Rheumatology (Oxford) 2000; 39 (4) 407-416
    CrossrefPubMedGoogle Scholar
  • 23 Ostergaard M, Stoltenberg M, Løvgreen-Nielsen P, Volck B, Sonne-Holm S, Lorenzen I. Quantification of synovitis by MRI: correlation between dynamic and static gadolinium-enhanced magnetic resonance imaging and microscopic and macroscopic signs of synovial inflammation. Magn Reson Imaging 1998; 16 (7) 743-754
    CrossrefPubMedGoogle Scholar
  • 24 Szkudlarek M, Court-Payen M, Strandberg C, Klarlund M, Klausen T, Ostergaard M. Power Doppler ultrasonography for assessment of synovitis in the metacarpophalangeal joints of patients with rheumatoid arthritis: a comparison with dynamic magnetic resonance imaging. Arthritis Rheum 2001; 44 (9) 2018-2023
    CrossrefPubMedGoogle Scholar
  • 25 Koski JM. Doppler imaging and histology of the synovium. J Rheumatol 2012; 39 (2) 452-453
    CrossrefPubMedGoogle Scholar
  • 26 Kawashiri SY, Kawakami A, Iwamoto N , et al. The power Doppler ultrasonography score from 24 synovial sites or 6 simplified synovial sites, including the metacarpophalangeal joints, reflects the clinical disease activity and level of serum biomarkers in patients with rheumatoid arthritis. Rheumatology (Oxford) 2011; 50 (5) 962-965
    CrossrefPubMedGoogle Scholar
  • 27 Klauser A, Demharter J, De Marchi A , et al; IACUS study group. Contrast enhanced gray-scale sonography in assessment of joint vascularity in rheumatoid arthritis: results from the IACUS study group. Eur Radiol 2005; 15 (12) 2404-2410
    CrossrefPubMedGoogle Scholar
  • 28 Platzgummer H, Schueller G, Grisar J, Weber M, Schueller-Weidekamm C. Quantification of synovitis in rheumatoid arthritis: do we really need quantitative measurement of contrast-enhanced ultrasound?. Eur J Radiol 2009; 71 (2) 237-241
    CrossrefPubMedGoogle Scholar
  • 29 Grassi W, Davies A, Boumendil O. Recent trends and technology advances in rheumatoid arthritis clinical ultrasonography and power Doppler imaging. Eur Musculoskel Rev 2011; 6 (3) 148-152
    PubMedGoogle Scholar
  • 30 Naredo E, Möller I, Acebes C , et al. Three-dimensional volumetric ultrasonography. Does it improve reliability of musculoskeletal ultrasound?. Clin Exp Rheumatol 2010; 28 (1) 79-82
    PubMedGoogle Scholar
  • 31 Klauser AS, Faschingbauer R, Jaschke WR. Is sonoelastography of value in assessing tendons?. Semin Musculoskelet Radiol 2010; 14 (3) 323-333
    Artikel in Thieme ConnectPubMedGoogle Scholar
  • 32 Lalitha P, Reddy MCh, Reddy KJ. Musculoskeletal applications of elastography: a pictorial essay of our initial experience. Korean J Radiol 2011; 12 (3) 365-375
    CrossrefPubMedGoogle Scholar