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Horm Metab Res 1971; 3(1): 21-23
DOI: 10.1055/s-0028-1095041
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© Georg Thieme Verlag KG Stuttgart · New York

The Effect of Streptozotocin on the Fine Structure of the Beta Cell of the Cod Pancreas

N. W. Thomas
  • Department of Anatomy, Marischal College, University of Aberdeen, Scotland
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Publication History

Publication Date:
07 January 2009 (online)

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Abstract

Fine structural studies have been made on the pancreatic beta cell of the cod following treatment with streptozotocin. The beta cells from treated fish contain increased numbers of lysosomes which contain secretory granules. In some cells aberrant granules have been observed.

It appears that the drug may inhibit granule release and also interfere with normal secretory granule production.

Key words

Streptozotocin - Beta Cell of Cod - Inhibition of Insulin Secretion - Intracellular Digestion of Granules

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