Die altersbedingte Makuladegeneration (AMD) ist weiterhin die häufigste Erblindungsursache
im höheren Alter in der westlichen Welt. Aufgrund des demografischen Wandels wird
die AMD zu einer zunehmenden Herausforderung für die öffentliche Gesundheit. Der Beitrag
stellt die aktuellen Erkenntnisse über Pathophysiologie, Klassifikation und Diagnostik
der AMD dar, um ein besseres Verständnis dieser Erkrankung zu ermöglichen.
Abstract
Age-related macular degeneration (AMD) continues to be the most common hereditary
disease among older people in the western world. In addition to the clinical examination,
multimodal imaging with fluorescein angiography, optical coherence tomography, fundus
autofluorescence and fundus photography are crucial for the correct diagnosis and
classification. This is particularly important with regard to risk assessment for
the development of a late form of the disease. Since the introduction of intravitreal
therapy against vascular endothelial growth factor (VEGF), the treatment options for
neovascular AMD have increased significantly and the prognosis for patients in terms
of maintaining their vision has improved. The hope is to develop stronger and longer-lasting
drugs and also to obtain approval for drugs to treat geographic atrophy. It is therefore
of great importance to be able to make a quick and correct diagnosis for patients.
In this paper we want to present an overview of
the pathophysiology, classification and diagnosis of AMD.
Schlüsselwörter
Altersbedingte Makuladegeneration - AMD - intravitreale Medikamenteneingabe - Netzhaut
- Makula
Keywords
age-related macular degeneration - AMD - intravitreal injection - retina - macula
