Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000036.xml
Laryngorhinootologie 2022; 101(09): 736-740
DOI: 10.1055/a-1830-8298
DOI: 10.1055/a-1830-8298
Originalarbeit
Pembrolizumab und Cetuximab als therapeutische Optionen für adenoidzystische Karzinome des Kopf-Hals-Bereiches
Pembrolizumab and Cetuximab as therapeutic options for ACC in head and neck
Schlüsselwörter
Adenoid-zystisches Karzinom - Kopf-Hals-Tumore - ex vivo - FLAVINO-Assay - Chemoresponse-Test - Pembrolizumab - Cetuximab - Immun-Checkpoint-Blockade - PD-1/PD-L1 SignalwegKeywords
Adenoid-cystic carcinoma (ACC) - head and neck cancer - FLAVINO assay - chemoresponse test - pembrolizumab - cetuximabPublication History
Received: 14 October 2021
Accepted after revision: 14 April 2022
Article published online:
16 May 2022
© 2022. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
References
- 1 Bilroth T. Germany: G Riemer; 1856. The Cylindroma Studies on the development of the blood vessels along with observations from the Royal University Surgical Clinic Berlin.55–69.
- 2 Bubendorf L, Feichter GE, Obermann EC. et al. Pathologie – Zytopathologie.
- 3 Böcker W, Denk H, Heitz PU. et al. Lehrbuch Pathologie. Elsevier Health Sciences. 2019
- 4 Martinez-Rodriguez N, Leco-Berrocal I, Rubio-Alonso L. et al. Epidemiology and treatment of adenoid cystic carcinoma of the minor salivary glands: a meta-analytic study. Med Oral Patol Oral Cir Bucal 2011; 16 (07) e884-e889 DOI: 10.4317/medoral.17200. (PMID: 21743416)
- 5 Miglianico L, Eschwege F, Marandas P. et al. Cervico-facial adenoid cystic carcinoma: study of 102 cases. Influence of radiation therapy. Int J Radiat Oncol Biol Phys 1987; 13 (05) 673-678 DOI: 10.1016/0360-3016(87)90284-7. (PMID: 3032876)
- 6 Hosni A, Huang SH, Goldstein D. et al. Outcomes and prognostic factors for major salivary gland carcinoma following postoperative radiotherapy. Oral Oncol 2016; 54: 75-80 DOI: 10.1016/j.oraloncology.2015.11.023. (PMID: 26723908)
- 7 Licitra L, Cavina R, Grandi C. et al. Cisplatin, doxorubicin and cyclophosphamide in advanced salivary gland carcinoma. A phase II trial of 22 patients. Ann Oncol 1996; 07 (06) 640-642 DOI: 10.1093/oxfordjournals.annonc.a010684. (PMID: 8879381)
- 8 Hill M, Constenla D, Ahern R. et al. Cisplatin and 5-fluorouracil for symptom control in advanced salivary adenoid cystic carcinoma. Oral Oncol 1997; 33 (04) 275-278
- 9 Suzuki S, Dobashi Y, Minato H. et al. EGFR and HER2–Akt–mTOR signaling pathways are activated in subgroups of salivary gland carcinomas. Virchows Archiv 2012; 461 (03) 271-282 DOI: 10.1007/s00428-012-1282-3. (PMID: 22828828)
- 10 Sridharan V, Gjini E, Liao X. et al. Immune Profiling of Adenoid Cystic Carcinoma: PD-L2 Expression and Associations with Tumor-Infiltrating Lymphocytes. Cancer Immunol Res 2016; 04 (08) 679-687 DOI: 10.1158/2326-6066.CIR-16-0031. (PMID: 27312343)
- 11 Hitre E, Budai B, Takacsi-Nagy Z. et al. Cetuximab and platinum-based chemoradio- or chemotherapy of patients with epidermal growth factor receptor expressing adenoid cystic carcinoma: a phase II trial. Br J Cancer 2013; 109 (05) 1117-1122 DOI: 10.1038/bjc.2013.468. (PMID: 23942070)
- 12 Mahmood U, Bang A, Chen YH. et al. A Randomized Phase 2 Study of Pembrolizumab With or Without Radiation in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma. Int J Radiat Oncol Biol Phys 2020; DOI: 10.1016/j.ijrobp.2020.08.018. (PMID: 32781104)
- 13 Moskaluk CA. Adenoid cystic carcinoma: clinical and molecular features. Head Neck Pathol 2013; 07 (01) 17-22 DOI: 10.1007/s12105-013-0426-3. (PMID: 23463073)
- 14 Azumi N, Battifora H. The cellular composition of adenoid cystic carcinoma. An immunohistochemical study 1987; 60 (07) 1589-1598 DOI: 10.1002/1097-0142(19871001)60:7<1589::aid-cncr2820600729>3.0.co;2-u. (PMID: 2441847)
- 15 Caselitz J, Schulze I, Seifert G. Adenoid cystic carcinoma of the salivary glands: an immunohistochemical study. J Oral Pathol 1986; 15 (06) 308-318 DOI: 10.1111/j.1600-0714.1986.tb00631.x. (PMID: 2428959)
- 16 Bell D, Roberts D, Kies M. et al. Cell type-dependent biomarker expression in adenoid cystic carcinoma. Cancer 2010; 116 (24) 5749-5756 DOI: 10.1002/cncr.25541. (PMID: 20824717)
- 17 Da Cruz Perez DE, De Abreu Alves F, Nobuko Nishimoto I. et al. Prognostic factors in head and neck adenoid cystic carcinoma. Oral Oncology 2006; 42 (02) 139-146 DOI: 10.1016/j.oraloncology.2005.06.024. (PMID: 16249115)
- 18 Dillon PM, Chakraborty S, Moskaluk CA. et al. Adenoid cystic carcinoma: A review of recent advances, molecular targets, and clinical trials. Head & Neck 2016; 38 (04) 620-627 DOI: 10.1002/hed.23925. (PMID: 25487882)
- 19 Amit M, Binenbaum Y, Trejo-Leider L. et al. International collaborative validation of intraneural invasion as a prognostic marker in adenoid cystic carcinoma of the head and neck. Head & Neck 2015; 37 (07) 1038-1045 DOI: 10.1002/hed.23710. (PMID: 24710845)
- 20 Dietz A, Boehm A, Horn IS. et al. Assay-based response evaluation in head and neck oncology: requirements for better decision making. Eur Arch Otorhinolaryngol 2010; 267 (04) 483-494 DOI: 10.1007/s00405-009-1191-5. (PMID: 20052589)
- 21 Chae YK, Chung SY, Davis AA. et al. Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling. Oncotarget 2015; 06 (35) 37117-37134 DOI: 10.18632/oncotarget.5076. (PMID: 26359351)
- 22 Jagielska B, Sarnowska E, Sarnowski T. et al. Contemporary diagnostic and therapeutic possibilities in patients with adenoid cystic carcinoma of the head and neck. Oncology in Clinical Practice 2020; 16 (01) 1-8
- 23 Papaspyrou G, Hoch S, Rinaldo A. et al. Chemotherapy and targeted therapy in adenoid cystic carcinoma of the head and neck: a review. Head Neck 2011; 33 (06) 905-911 DOI: 10.1002/hed.21458. (PMID: 20652885)
- 24 Lagha A, Chraiet N, Ayadi M. et al. Systemic therapy in the management of metastatic or advanced salivary gland cancers. Head & Neck Oncology 2012; 04 (01) 19 DOI: 10.1016/j.oraloncology.2018.01.034. (PMID: 29496053)
- 25 Subramaniam T, Lennon P, O’Neill JP. Ongoing challenges in the treatment of adenoid cystic carcinoma of the head and neck. Irish Journal of Medical Science (1971 -) 2015; 184 (03) 583-590 DOI: 10.1007/s11845-015-1298-1. (PMID: 25894281)
- 26 Gessner K, Wichmann G, Boehm A. et al. Therapeutic options for treatment of Merkel cell carcinoma. Eur Arch Otorhinolaryngol 2011; 268 (03) 443-448 DOI: 10.1007/s00405-010-1354-4. (PMID: 20799041)
- 27 Liu NN, Zhang SL, Chen W. The cross-contaminated cell lines of adenoid cystic carcinoma: A crucial concern. Translational Surgery 2017; 02 (01) 10-13