Homeopathy 2007; 96(03): 151-157
DOI: 10.1016/j.homp.2007.03.006
 
Copyright © The Faculty of Homeopathy 2007

The history of the Memory of Water

Yolène Thomas

Subject Editor:
Further Information

Publication History

Received26 March 2007

accepted27 March 2007

Publication Date:
13 December 2017 (online)

‘Homeopathic dilutions’ and ‘Memory of Water’ are two expressions capable of turning a peaceful and intelligent person into a violently irrational one,’ as Michel Schiff points out in the introduction of his book ‘The Memory of Water’. The idea of the memory of water arose in the laboratory of Jacques Benveniste in the late 1980s and 20 years later the debate is still ongoing even though an increasing number of scientists report they have confirmed the basic results.

This paper, first provides a brief historical overview of the context of the high dilution experiments then moves on to digital biology. One working hypothesis was that molecules can communicate with each other, exchanging information without being in physical contact and that at least some biological functions can be mimicked by certain energetic modes characteristics of a given molecule. These considerations informed exploratory research which led to the speculation that biological signaling might be transmissible by electromagnetic means. Around 1991, the transfer of specific molecular signals to sensitive biological systems was achieved using an amplifier and electromagnetic coils. In 1995, a more sophisticated procedure was established to record, digitize and replay these signals using a multimedia computer. From a physical and chemical perspective, these experiments pose a riddle, since it is not clear what mechanism can sustain such ‘water memory’ of the exposure to molecular signals. From a biological perspective, the puzzle is what nature of imprinted effect (water structure) can impact biological function. Also, the far-reaching implications of these observations require numerous and repeated experimental tests to rule out overlooked artifacts. Perhaps more important is to have the experiments repeated by other groups and with other models to explore the generality of the effect. In conclusion, we will present some of this emerging independent experimental work.

 
  • References

  • 1 Benveniste J., Henson P.M., Cochrane C.G. Leukocyte-dependent histamine release from rabbit platelets. The role of IgE, basophils, and a platelet-activating factor. J Exp Med 1972; 136: 1356-1377.
  • 2 Benveniste J. Platelet-activating factor, a new mediator of anaphylaxis and immune complex deposition from rabbit and human basophils. Nature 1974; 249: 581-582.
  • 3 Davenas E., Poitevin B., Benveniste J. Effect of mouse peritoneal macrophages of orally administered very high dilutions of silica. Eur J Pharmacol 1987; 135: 313-319.
  • 4 Poitevin B., Davenas E., Benveniste J. In vitro immunological degranulation of human basophils is modulated by lung histamine and Apis mellifica. Br J Clin Pharmacol 1988; 25: 439-444.
  • 5 Walach H., Jonas W.B., Ives J., van Wijk R., Weingartner O. Research on homeopathy: state of the art. J Altern Complement Med 2005; 11: 813-829.
  • 6 Bellavite P., Ortolani R., Pontarollo F., Piasere V., Benato G., Conforti A. Immunology and Homeopathy. Evidence-based Complementary Alternative Med 2005; 2: 441-452.
  • 7 Davenas E., Beauvais F., Amara J. et al. Human basophil degranulation triggered by very dilute antiserum against IgE. Nature 1988; 333: 816-818.
  • 8 Maddox J., Randi J., Stewart W.W. High-dilution’experiments a delusion. Nature 1988; 334: 287-290.
  • 9 Schiff M. The Memory of Water. UK: Ed. Thorsons, 1995.
  • 10 Benveniste J. Dr Jacques Benveniste replies. Nature 1988; 334: 291.
  • 11 Benveniste J., Davenas E., Ducot B., Cornillet B., Poitevin B., Spira A. L’agitation de solutions hautement diluées n’induit pas d’activité biologique spécifique. CR Acad Sci Paris 1991; 312: 461-466.
  • 12 Belon P., Cumps J., Ennis M. et al. Inhibition of human basophil degranulation by successive histamine dilutions: results of a European multi-centre trial. Inflamm Res (Suppl 1) 1999; 48: S17-S18.
  • 13 Belon P., Cumps J., Ennis M. et al. Histamine dilutions modulate basophil activation. Inflamm Res 2004; 53: 181-188.
  • 14 Lobyshev VI, Tomkevitch MS. Luminescence study of homeopathic remedies. In: Priezzhev AV, Cote GL (eds). Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring, Proceedings of the SPIE, Vol 4263. MAIK “Navka/Interperiodica” (Russia), 2001, pp 1605–7422.
  • 15 Elia V., Baiano S., Duro I., Napoli E., Niccoli M., Nonatelli L. Permanent physico-chemical properties of extremely diluted aqueous solutions of homeopathic medicines. Homeopathy 2004; 93: 144-150.
  • 16 Del Giudice E., Preparata G., Vitiello G. Water as a free electric dipole laser. Phys Rev Lett 1988; 61: 1085-1088.
  • 17 Preparata G. QED Coherence in Matter. Singapore: World Scientific; 1995.
  • 18 Fesenko E.E., Gluvstein A.Y. Changes in the state of water, induced by radiofrequency electromagnetic fields. FEBS Lett 1995; 367: 53-55.
  • 19 Goodman R., Blank M. Initial interactions in electromagnetic field-induced biosynthesis. J Cell Physiol 2004; 199: 359-363.
  • 20 Ben Jacob E., Aharonov Y., Shapira Y. Bacteria harnessing complexity. Biofilms 2004: 239-263.
  • 21 Vallée P.h., Lafait J., Mentré P., Monod M.O., Thomas Y. Effects of pulsed low frequency electromagnetic fields on water using photoluminescence spectroscopy: role of bubble/water interface?. J Chem Phys 2005; 122: 114513-114521.
  • 22 Albrecht-Buehler G. Rudimentary form of cellular ‘vision’. Proc Natl Acad Sci USA 1992; 89: 8288-8292.
  • 23 Trushin M.W. Studies on distant regulation of bacterial growth and light emission. Microbiology 2003; 149: 363-368.
  • 24 Ninham B.W., Boström M. Building bridges between the physical and biological sciences. Cell Mol Biol 2005; 51: 803-813.
  • 25 Thomas Y., Schiff M., Belkadi L., Jurgens P., Kahhak L., Benveniste J. Activation of human neutrophils by electronically transmitted phorbol-myristate acetate. Med Hypotheses 2000; 54: 33-39.
  • 26 Thomas Y., Kahhak L., Aissa J. The physical nature of the biological signal, a puzzling phenomenon: the critical role of Jacques Benveniste. in: Pollack G.H., Cameron I.L., Wheatley D.N. Water and the Cell. 2006. Dordrecht: Springer; 325-340.
  • 27 Wiesenfeld K., Moss F. Stochastic resonance and the benefits of noise: from ice ages to crayfish and SQUIDS. Nature 1995; 373: 33-36.
  • 28 Banwellk C.N. Fundamentals of Molecular Spectroscopy. UK: McGraw-Hill Publ.; 1983. pp 26–28.
  • 29 Dunne B.J., Jahn R.G. Consciousness, information, and living systems. Cell Mol Biol 2005; 51: 703-714.
  • 30 Jonas W.B., Ives J.A., Rollwagen F. et al. Can specific biological signals be digitized?. FASEB J 2006; 20: 23-28.