DOI : 10.1055/s-00034925

Hämostaseologie

Issue S 01 · Volume 44 · February 2024 DOI: 10.1055/s-014-59184


GTH Congress 2024 – 68th Annual Meeting of the Society of Thrombosis and Haemostasis Research – Building Bridges in Coagulation
Vienna, Austria, 27.–01.03.2024

Congress Presidents:
Ao. Prof. Dr. Christoph Male, Prof. PD Dr. Cihan Ay
Abstracts (HTML) Abstracts (PDF) List of Authors
T-07-01
Ismail, A. M.; Batty, P.; Mo, A.; Yates, B.; Harpell, L.; Menard, A.; Pender, A.; Khattak, N.; Razon, L.; Winterborn, A.; Fong, S.; Lillicrap, D.; Harris, S.: Early Changes in Liver Transcriptomic Profiles Following Adeno-Associated Viral Gene Therapy in the Severe Hemophilia A Dog Model
T-07-02
Bernar, A.; Gebetsberger, J.; Bauer, M.; Schirmer, M.; Streif, W.: Beyond bleeding: Exploring coagulation factors and cytokines in bone health in vitro
T-07-03
Brühl, M.; Tomschi, F.; Schmidt, A.; Ransmann, P.; Strauss, A. C.; Hilberg, T.: Fall risk in patients with haemophilia: A case-control study on clinical motor performance tests
T-07-04
Schmidt, A.; Sigl-Kraetzig, M.; Richter, H.; Vogler, T.; Tomschi, F.; Hilberg, T.: Prevalence of synovitis and osteochondral damage in relation to age and BMI in patients with haemophilia
T-07-05
Stano Kozubik, K.; Hynst, J.; Svozilova, H.; Stika, J.; Vrzalova, Z.; Likavcova, P.; Blahakova, I.; Pospisilova, S.; Doubek, M.: Frequency of Pathogenic Variants for Hereditary Bleeding Disorders in General Czech Population
T-07-06
Haack, L.; Dasenbrook, B.; Krammer-Steiner, B.; Stubert, J.: Pregnancy Outcome in Women with von Willebrand Disease Following Fertility Treatment: A Retrospective Cohort Analysis
T-07-07
Pipe, S.; van der Valk, P.; Verhamme, P.; Kampmann, P.; Leebeek, F.; Coppens, M.; Meijer, K.; Raheja, P.; Key, N.; Visweshwar, N.; Young, G.; Lemons, R.; Klamroth, R.; Miesbach, W.; Astermark, J.; O’Connell, N.; Kazmi, R.; Galante, N.; le Quellec, S.; Monahan, P.; Hermans, C.: Etranacogene Dezaparvovec Shows Sustained Efficacy and Safety in Adult Patients With Severe or Moderately Severe Haemophilia B 3 Years After Administration in the HOPE-B Trial
T-07-08
Agarwal, S.; Hermans, C.; Miesbach, W.; Pipe, S.; Sidonio, R.; Osmond, D.; Newman, V.; Henshaw, J.; Peyvandi, F.: A simulation study to provide guidance for individuals transitioning from emicizumab to valoctocogene roxaparvovec
T-07-09
Mahlangu, J.; Ozelo, M.; Tan, C. W.; Giermasz, A.; Wang, J.-D.; Harris, S.; Osmond, D.; Yu, H.; Robinson, T.: Bleeding Outcomes in Participants with Factor VIII Activity<5 IU/dL post–gene transfer in GENEr8-1
T-07-10
Goldmann, G.; Marquardt, N.; Oldenburg, J.: New inSight Joint Health tool: Focusing on long-term joint health
T-07-11
Hopp, M.-T.; Ugurlar, D.; Pezeshkpoor, B.; Oldenburg, J.; Imhof, D.: Molecular, structural, and functional insights into the interaction of coagulation factor VIII with hemorrhage-derived heme
T-07-12
Pezeshkpoor, B.; Berkemeier, A.-C.; Herbst, K.; Albert, T.; Müller, J.; Oldenburg, J.: Detection and domain characterization of anti-FVIII antibodies: Comparative evaluation of NBA and immunoassays
T-07-13
Müller, J.; Albert, T.; Klein, C.; Horneff, S.; Rühl, H.; Pötzsch, B.; Goldmann, G.; Marquardt, N.; Oldenburg, J.: Lonoctocog alfa vs. octocog alfa: incremental recovery and extended coagulation analysis
T-07-14
Olivieri, M.; Juranek, S.; Langer, F.; Escuriola-Ettingshausen, C.; Klamroth, R.; Sachs, U. J.; Niekrens, C.; von Depka Prondzinski, M.; Scholz, U.; Kalus, M.; Linhoff, T.; Oldenburg, J.: An update on real-world use of rVIII‑SingleChain in patients with haemophilia A in Germany: Interim results from a prospective, non-interventional study
T-07-15
Abdelmageed, A.; Jurado-Mestre, B.; Kotov, V.; Schötz, S. L.; Gerritzen, H.; Albert, T.; Oldenburg, J.; Heine, A.; Kurts, C.; Becker-Gotot, J.: Staphylococcus aureus infection restimulates inhibitor production in tolerized hemophilia A mice
T-07-16
von Drygalski, A.; Königs, C.; Nagae, C.; Dumont, J.; Bystricka, L.; Willemze, A.; Santagostino, E.; Oldenburg, J.: Change in Hemophilia Joint Health Score (HJHS) During the Phase 3 XTEND-1 Study of Efanesoctocog Alfa in Patients With Severe Hemophilia A
T-07-17
Langer, F.; Escuriola-Ettingshausen, C.; Pfrepper, C.; Miesbach, W.; Stähler, R.; Schepperle, C.; Weik, K.; Scheibler, F.: Development of a digital patient decision aid for bleeding prophylaxis in severe hemophilia A
T-07-18
Weyand, A.; Königs, C.; Meunier, S.; Amano, K.; Bystricka, L.; Neill, G.; Abad-Franch, L.; Willemze, A.; Tosetto, A.: Treatment of Bleeding Episodes With Efanesoctocog Alfa in Patients With Severe Haemophilia A in the Phase 3 XTEND-1 Study
T-07-19
Oldenburg, J.; Olivieri, M.; Wenning, S.; Holzhauer, S.; Krammer-Steiner, B.; Escuriola-Ettingshausen, C.; Klamroth, R.; Miesbach, W.; Linhoff, T.; Pfrepper, C.: Real-world use of rIX-FP in patients with haemophilia B: Interim results from a prospective, non-interventional study in Germany
T-07-20
Ramaraje Urs, S. U.; Pellequer, J. L.; Teulon, J. M.; Singh, S.; Oldenburg, J.; Biswas, A.: In-detail AFM analysis of the different conformational states of full-length coagulation Factor VIII and FVIII-vWF complex.
T-07-21
Kürschner, M.; Lohse, J.; Boiti, F.; Tiebel, O.; Knoefler, R.: Evaluation of primary haemostasis in children and young adults with haemophilia
T-07-22
Knowles, L. M.; Wolter, C.; Menger, M. D.; Laschke, M. W.; Haegele, F.; Eichler, H.; Pilch, J.: Interleukin-6 as a Plasma Marker of Bleeding in Patients with Hemophilia
T-07-23
Wieland, I.; Becker, K.; Stichel, D.; Christoph, K.: Development of a low-titer inhibitor in a boy with congenital mild hemophilia A: clinical and immunological follow up of 1 year
T-07-24
Hüsing, A.; Goudemand, J.; Borel Derlon, A.; Henriet, C.; Boiffin, B.; Repesse, Y.; Susen, S.: A Pooled Analysis of Treatment with a Plasma-Derived von Willebrand Factor (VWF) Almost Devoid of Factor VIII in Paediatric Patients with Von Willebrand Disease (VWD)
T-07-25
Trappl, M.; Vostatek, R.; Kraemmer, D.; Hohensinner, P.; Pabinger, I.; Ay, C.: Association of telomere length, a marker of biological aging, with hemophilia severity
T-07-26
Rösch, A.; Schmoldt, D.: The change in factor VIII therapy since the introduction of mandatory pharmacy reporting in the GSAV in Germany – a retrospective data analysis from smart medication ScanDoc over 3 years
T-07-27
Kieninger, S.; Wolska, N.; Zlamal, J.; Bakchoul, T.; Althaus, K.: Platelet-dependent thrombin generation in hemophilia A patients may compensate low FVIII levels
T-07-28
Althaus, K.; Schreieck, J.; Hammer, S.; Bakchoul, T.: Artrial fibrillation – a challenge in patients with hemophilia A
T-07-29
Arshad, M.; Dreisbach, E.; Brehm, M. A.: Downregulation of von Willebrand factor induces endothelial barrier dysfunction
T-07-30
Selmeczi, A.; Nemes, L.; Boda, Z.; Schlammadinger, Á.; Szegedi, I.; Göncziné Kiss, J.; Zombori, M.; Vezendi, K.; Marton, I.; Alizadeh, H.; Bereczky, Z.; Kiss, C.: Von Willebrand disease in Hungary – results of the national von Willebrand registry
T-07-31
Ransmann, P.; Brühl, M.; Hmida, J.; Tomschi, F.; Goldmann, G.; Oldenburg, J.; Wirtz, D.; Hilberg, T.; Strauss, A. C.: Physical activity, bone mineral density, and lean mass in patients with haemophilia
T-07-32
Oldenburg, J.; Pipe, S. W.; Collins, P.; Dhalluin, C.; Kenet, G.; Schmitt, C.; Buri, M.; Jiménez-Yuste, V.; Peyvandi, F.; Young, G.; Mancuso, M. E.; Kavakli, K.; Kiialainen, A.; Niggli, M.; Chang, T.; Lehle, M.; Fijnvandraat, K.: Emicizumab Prophylaxis for the Treatment of Infants with Severe Haemophilia A without Factor VIII Inhibitors: Primary Analysis of the HAVEN 7 Study
T-07-33
Krahforst, A.; Yadegari, H.; Pezeshkpoor, B.; Pavlova, A.; Halimeh, S.: Unraveling the Molecular Pathogenesis and Mutation Spectrum of Quantitative VWD: Type 1, Low VWF, and Type 3
T-07-34
Hambardzumyan, L.; Pabinger, I.; Tamamyan, G.; Danelyan, S.; Araqelyan, S.; Petrosyan, L.; Vardumyan, E.; Sargsyan, N.; Khachatryan, H.: A Unique Clinical Case of Using Emicizumab as an Effective Therapeutic Approach for Refractory Acquired Hemophilia
T-07-35
Provaznikova, D.; Radovska, A.; Simonikova, M.; Salaj, P.; Drbohlavova, E.; Smejkal, P.; Zapotocka, E.; Hrachovinova, I.: Phenotype-genotype correlation in patients with non-severe haemophilia A and intronic variants of F8
T-07-36
Milanov, P.; Roth, S.; Griesheimer, A.; Weiss, J.; Holm, K. B.; Sumera, A. J.; Ziemele, B. M.; Miesbach, W.: Assessing Adherence to Prophylactic Treatment in Patients with Haemophilia from Five European Countries
T-07-37
Al Rifai, R.; Jamil, M. A.; Nüsgen, N.; Altmüller, J.; Oldenburg, J.; El-Maarri, O.: The miRNAs present in LSECs play pivotal role in defining their cellular identity and have an impact on the regulation of F8 gene expression
T-07-38
Kraemmer, D.; Königsbrügge, O.; Pabinger, I.; Ay, C.: Vitamin D and Parathyroid Hormone in Hemophilia
T-07-39
Kanthack, L.; Brodt, G.; Mentzel, H.-J.; Knoefler, R.; Kim, S.; Kühnöl, C.; Hagedorn, N.; Kentouche, K.: Evaluation of Quantitative Osteodensitometry in children and young adults with hemophilia – Results of the EQUOHÄM Study of the KHDO
T-07-40
Möller, R.; Baulain, U.; Petersen, B.; Detering, C.; Ekhlasi-Hundrieser, M.; Kaiser, K.; Zimmermann, R.; Mühlfeld, C.; von Depka Prondzinski, M.; Gutensohn, K.; Lehner, S.; Pfarrer, C.: Angiodysplasia and other Vascular Structural Changes in Von Willebrand Disease
T-07-41
Pfrepper, C.; Siecke, A.; Klamroth, R.; Kühnöl, C.; Kentouche, K.; Holzhauer, S.; Fischer, L.; Aumann, V.; Trautmann-Grill, K.; Scholz, U.; Halm-Heinrich, I.; Krammer-Steiner, B.; Schilling, K.; Hagedorn, N.; Knoefler, R.: Changes in hemophilia treatment in the eastern part of Germany between 2015 and 2021 – data from the Kompetenznetz Hämorrhagische Diathese Ost (KHDO)
T-07-42
Halimeh, S.; Zappek, J.; Siebert, M.; Daoud, A.; Habermann, B.: Enhancing Joint Health in Hemophilic Patients: A Retrospective Cohort Study on Early Detection and Intervention for Synovitis
T-07-43
Heinrichs, D.; Siebert, M.; Halimeh, S.: Understanding the Psychosocial Impact on Hemophilia Carriers
T-07-44
El Hazzouri, S.; Nüsgen, N.; Oldenburg, J.; El-Maarri, O.: Investigating the Role of GABARAP in FVIII Trafficking: A Comparative Study of Cellular Responses to Pathway Disturbances
T-07-45
Hammer, S.; Wekerle, M.; Strauss, M.; Kieninger, S.; Heuer, L.; Althaus, K.; Bakchoul, T.: Blood viscoelastic testing could support the management of patients with hemophilia A
T-07-46
Oldenburg, J.; Wenning, S.; Holstein, K.; Filip, J.; Miesbach, W.; Severin, K.; Eichler, H.; Halimeh, S.: HEM-POWR study: Fourth interim analysis evaluating real-world effectiveness and safety of damoctocog alfa pegol in previously treated patients with haemophilia A in Germany
T-07-47
Pipe, S.; Gomez, E.; Hermans, C.; Giermasz, A.; Kampmann, P.; Lemons, R.; Galante, N.; le Quellec, S.; Monahan, P.: HIV Comorbid Infection and Etranacogene Dezaparvovec Therapy: Efficacy and Safety Results From Phase 2b and Pivotal Phase 3 HOPE-B Trials 3 Years after Administration
T-07-48
German Paediatric Haemophilia Research Database – Update 2023