DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Issue 11 · Volume 102 · 2009 DOI: 10.1055/s-008-36065

Editorial Focus

  • 799
    Hayward, Catherine P. M.:

    Advances in Understanding “High on-Treatment Platelet Reactivity”

    • Theme Issue Editorial

  • 801
    Harenberg, Job; Casu, Benito:

    Heparin and its derivatives - Present and future

    • Theme Issue Article

  • 804
    Petitou, Maurice; Nancy-Portebois, Vanessa; Dubreucq, Guy; Motte, Vincent; Meuleman, Dick; de Kort, Martin; van Boeckel, Constant A. A.; Vogel, Gerard M. T.; Wisse, Jeffry A. J.:

    From heparin to EP217609: The long way to a new pentasaccharide-based neutralisable anticoagulant with an unprecedented pharmacological profile

  • 811
    Harenberg, Job:

    Development of idraparinux and idrabiotaparinux for anticoagulant therapy

  • 816
    Schlesinger, Martin; Simonis, Dirk; Schmitz, Patrick; Fritzsche, Juliane; Bendas, Gerd:

    Binding between heparin and the integrin VLA-4

  • 823
    Li, Jin-ping; Vlodavsky, Israel:

    Heparin, heparan sulfate and heparanase in inflammatory reactions

  • 829
    Fonseca, Roberto J. C.; Santos, Gustavo R. C.; Mourão, Paulo A. S.:

    Effects of polysaccharides enriched in 2,4-disulfated fucose units on coagulation, thrombosis and bleeding

  • 837
    Collino, Massimo; Castiglia, Sara; Manoni, Marco; Salsini, Liana; Chini, Jacopo; Masini, Emanuela; Fantozzi, Roberto:

    Effects of a semi-synthetic N-,O-sulfated glycosaminoglycan K5 polysaccharide derivative in a rat model of cerebral ischaemia/ reperfusion injury

  • 846
    Liverani, Lino; Mascellani, Giuseppe; Spelta, Franco:

    Heparins: Process-related physico-chemical and compositional characteristics, fingerprints and impurities

  • 854
    Sasisekharan, Ram; Shriver, Zachary:

    From crisis to opportunity: A perspective on the heparin crisis

  • 859
    Szelke, Helga; Harenberg, Job; Krämer, Roland:

    Detection and neutralisation of heparin by a fluorescent ruthenium compound

  • 865
    Bisio, Antonella; Vecchietti, Davide; Citterio, Laura; Guerrini, Marco; Raman, Rahul; Bertini, Sabrina; Eisele, Giorgio; Naggi, Annamaria; Sasisekharan, Ram; Torri, Giangiacomo:

    Structural features of low-molecular-weight heparins affecting their affinity to antithrombin

  • 874
    Rudd, Timothy R.; Skidmore, Mark A.; Guimond, Scott E.; Holman, Joseph; Turnbull, Jeremy E.; Lauder, Robert M.; Fernig, David G.; Yates, Edwin A.:

    The potential for circular dichroism as an additional facile and sensitive method of monitoring low-molecular-weight heparins and heparinoids

  • 879
    Vardi, Moshe; Laor, Arie; Bitterman, Haim:

    Activated partial thromboplastin time monitoring in patients receiving unfractionated heparin for venous thromboembolism in relation to clinical outcomes

  • 887
    Nowak, Götz:

    Heparin-induced thrombocytopenia (HIT II) – A drug-associated autoimmune disease

  • 892
    Laux, Volker; Perzborn, Elisabeth; Heitmeier, Stefan; von Degenfeld, Georges; Dittrich-Wengenroth, Elke; Buchmüller, Anja; Gerdes, Christoph; Misselwitz, Frank:

    Direct inhibitors of coagulation proteins – the end of the heparin and low-molecular-weight heparin era for anticoagulant therapy?

  • 900
    Kishimoto, Takashi Kei; Qi, Yi Wei; Long, Alison; Capila, Ishan; Sasisekharan, Ram; Guerrero, Luis; Fier, Ian; Roach, James; Venkataraman, Ganesh:

    M118 – A rationally engineered low-molecular-weight heparin designed specifically for the treatment of acute coronary syndromes

    • Issue Article

  • 907
    Guerrini, Marco; Shriver, Zachary; Bisio, Antonella; Naggi, Annamaria; Casu, Benito; Sasisekharan, Ram; Torri, Giangiacomo:

    The Tainted Heparin Story: An Update

    • Pro/Contra Article

  • 912
    Healey, Jeff S.:

    Pro: “Anti-platelet therapy is an alternative to oral anticoagulation for atrial fibrillation”

  • 914
    Apostolakis, Stavros; Shantsila, Eduard; Lip, Gregory Y. H.; Lane, Deirdre A.:

    Contra: “Anti-platelet therapy is an alternative to oral anticoagulation for atrial fibrillation”

    • Review Article

  • 916
    Shantsila, Eduard; Lip, Gregory Y. H.:

    The role of monocytes in thrombotic disorders

    • Blood Coagulation, Fibrinolysis and Cellular Haemostasis

  • 925
    Heinz, Stefan; Schüttrumpf, Jörg; Simpson, Jeremy C.; Pepperkok, Rainer; Nicolaes, Gerry A.; Abriss, Daniela; Milanov, Peter; Roth, Stefanie; Seifried, Erhard; Tonn, Torsten:

    Factor VIII-eGFP fusion proteins with preserved functional activity for the analysis of the early secretory pathway of factor VIII

  • 936
    Machlus, Kellie R.; Colby, Emily A.; Wu, Jogin R.; Koch, Gary G.; Key, Nigel S.; Wolberg, Alisa S.:

    Effects of tissue factor, thrombomodulin and elevated clotting factor levels on thrombin generation in the calibrated automated thrombogram

  • 945
    Agledahl, Ingvild; Brodin, Ellen; Svartberg, Johan; Hansen, John-Bjarne:

    Impact of long-term testosterone treatment on plasma levels of free TFPI and TF-induced thrombin generation ex vivo in elderly men with low testosterone levels

  • 951
    Spyropoulos, Alex C.; Hussein, Mohamed; Lin, Jay; Battleman, David:

    Rates of venous thromboembolism occurrence in medical patients among the insured population

    • Platelets and Blood Cells

  • 958
    Eshel-Green, Tal; Berny, Michelle A.; Conley, Robert B.; McCarty, Owen J. T.:

    Effect of sex difference on platelet adhesion, spreading and aggregate formation under flow

  • 966
    Brouckova, Adela; Holada, Karel:

    Cellular prion protein in blood platelets associates with both lipid rafts and the cytoskeleton

    • Endothelium and Vascular Development

  • 975
    Dardik, Rima; Livnat, Tami; Seligsohn, Uri:

    Variable effects of alpha v suppression on VEGFR-2 expression in endothelial cells of different vascular beds

    • Cardiovascular Biology and Cell Signalling

  • 983
    Massey, Philip G.; Tanaka, Shinji; Buckler, Joshua M.; Jiang, Bo; McCourtie, Anton; Qian, Kun; Tom, Clifford; Stempien-Otero, April; Wen, Shan; Luttrell, Ian; Chitaley, Kanchan; Dichek, David A.:

    Constriction of carotid arteries by urokinase-type plasminogen activator requires catalytic activity and is independent of NH2-terminal domains

    Online Supplementary Material (PDF) (PDF) Online Supplementary Material (PDF) (PDF)

    • Animal Models

  • 993
    Cleuren, Audrey C. A.; van Hoef, Berthe; Hoylaerts, Marc F.; van Vlijmen, Bart J. M.; Lijnen, H. Roger:

    Short-term ethinylestradiol treatment suppresses inferior caval vein thrombosis in obese mice

    • New Technologies, Diagnostic Tools and Drugs

  • 1001
    Dempfle, Carl-Erik; Zharkowa, Ulyana; Elmas, Elif; Ahmad-Nejad, Parviz; Neumaier, Michael; Borggrefe, Martin:

    Heptest-STAT, a new assay for monitoring of low-molecular-weight heparins, is not influenced by pregnancy-related changes of blood plasma