DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Issue 01 · Volume 99 · 2008 DOI: 10.1055/s-007-35402

Editorial Focus

2
Warkentin, Theodore E: Fondaparinux versus direct thrombin inhibitor therapy for the management of heparin-induced thrombocytopenia (HIT) – Bridging the River Coumarin

Review Article

4
Stasi, Roberto; Evangelista, Maria Laura; Stipa, Elisa; Buccisano, Francesco; Venditti, Adriano; Amadori, Sergio: Idiopathic thrombocytopenic purpura: Current concepts in pathophysiology and management
14
Crescente, Marilena; Castelnuovo, Augusto Di; Iacoviello, Licia; Vermylen, Jos; Cerletti, Chiara; Gaetano, Giovanni de: Response variability to aspirin as assessed by the platelet function analyzer (PFA)-100
27
Foss, Brynjar; Bruserud, Øystein: Platelet functions and clinical effects in acute myelogenous leukemia
38
Chaukiyal, Pooja; Nautiyal, Amit; Radhakrishnan, Sangeetha; Singh, Sonal; Navaneethan, Sankar D: Thromboprophylaxis in cancer patients with central venous catheters

Blood Coagulation, Fibrinolysis and Cellular Haemostasis

44
Gale, Andrew J; Rozenshteyn, Diana: Cathepsin G, a leukocyte protease, activates coagulation factor VIII
52
Musso, Roberto; Santagostino, Elena; Faradji, Albert; Iorio, Alfonso; Meer, Jan van der; Ingerslev, Jørgen; Lambert, Thierry; Maas-Enriquez, Monika; Gorina, Eduard; for the KOGENATE Bayer European PMS Study Group: Safety and efficacy of sucrose-formulated full-length recombinant factor VIII: Experience in the standard clinical setting
59
Pomp, Elisabeth R; Rosendaal, Frits R; Doggen, Carine J. M: Alcohol consumption is associated with a decreased risk of venous thrombosis
64
Schols, Saskia E. M; Meijden, Paola E. J. van der; Oerle, René van; Curvers, Joyce; Heemskerk, Johan W. M; Pampus, Elisabeth C. M. van: Increased thrombin generation and fibrinogen level after therapeutic plasma transfusion: Relation to bleeding
71
Schobess, Rosemarie; Kurnik, Karin; Friedrichs, Frauke; Halimeh, Susan; Krümpel, Anne; Bidlingmaier, Christoph; Nowak-Göttl, Ulrike: Effects of primary and secondary prophylaxis on the clinical expression of joint damage in children with severe haemophilia A
77
Kist, Willem J; Janssen, Nard G; Kalk, Jakoba J; Hague, William M; Dekker, Gustaaf A; de Vries, Johanna I. P.: Thrombophilias and adverse pregnancy outcome – A confounded problem!

Platelets and Blood Cells

86
Ray, Denise M; Spinelli, Sherry L; Pollock, Stephen J; Murant, Thomas I; O’Brien, Jamie J; Blumberg, Neil; Francis, Charles W; Taubman, Mark B; Phipps, Richard P: Peroxisome proliferator-activated receptor γ and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles
96
Haas, Thomas A: Discrete functional motifs reside within the cytoplasmic tail of αV integrin subunit
108
Mori, Daisuke; Yano, Koichiro; Tsubota, Ken-ichi; Ishikawa, Takuji; Wada, Shigeo; Yamaguchi, Takami: Simulation of platelet adhesion and aggregation regulated by fibrinogen and von Willebrand factor
116
Serebruany, Victor L; Malinin, Alex I; Hanley, Dan F: Magnitude and time course of platelet inhibition with extended release dipyridamole with or without aspirin in healthy Japanese volunteers
121
Sibbing, Dirk; Braun, Siegmund; Jawansky, Stefan; Vogt, Wolfgang; Mehilli, Julinda; Schömig, Albert; Kastrati, Adnan; Beckerath, Nicolas von: Assessment of ADP-induced platelet aggregation with light transmission aggregometry and multiple electrode platelet aggregometry before and after clopidogrel treatment

Letters to the Editor

99
Folsom, Aaron R; Peacock, James M; Boerwinkle, Eric; Cushman, Mary: β2-adrenergic receptor polymorphism and venous thromboembolism
238
Gerhardt, Andrea; Araba, Fatima; Scharf, Rüdiger E; Zotz, Rainer B: Report on a disease-adapted treatment in a patient with severe factor X deficiency resulting from a homozygous factor X gene mutation
239
Smout, Jonathan; Cleanthis, Marcus; Stansby, Gerard: Comment on "Hyperresponsiveness of platelets in ischemic stroke" by Fateh-Moghadam et al.
241
Palareti, Gualtiero; Agnelli, Giancarlo; Imberti, Davide; Moia, Marco; Ageno, Walter; Pistelli, Riccardo; Rossi, Romina; Verso, Melina; for the MASTER investigators: A commentary: To screen for calf DVT or not to screen? The highly variable practice among Italian centers highlights this important and still unresolved clinical option. Results from the Italian MASTER registry
244
Klok, Frederikus A; Zidane, Majida; Djurabi, Reza Karami; Nijkeuter, Mathilde; Huisman, Menno V: The physician’s estimation ‘alternative diagnosis is less likely than pulmonary embolism’ in the Wells rule is dependent on the presence of other required items
246
Marianne, Canonico; Valérie, Olié; Laure, Carcaillon; Pascale, Tubert-Bitter; Pierre-Yves, Scarabin; the EStrogen and THromboEmbolism Risk (ESTHER) Study Group; on behalf of: Synergism between non-O blood group and oral estrogen in the risk of venous thromboembolism among postmenopausal women: The ESTHER study

Wound Healing and Inflammation/Infection

127
Lijfering, Willem M; Vries, Aiko P. J. de; Veeger, Nic J. G. M; Son, Willem J. van; Bakker, Stephan J. L; Meer, Jan van der: Possible contribution of cytomegalovirus infection to the high risk of (recurrent) venous thrombosis after renal transplantation

Endothelium and Vascular Development

133
Nadir, Yona; Brenner, Benjamin; Gingis-Velitski, Sveta; Levy-Adam, Flonia; Ilan, Neta; Zcharia, Eyal; Nadir, Erez; Vlodavsky, Israel: Heparanase induces tissue factor pathway inhibitor expression and extracellular accumulation in endothelial and tumor cells

Cardiovascular Biology and Cell Signalling

142
Butenas, Saulius; Undas, Anetta; Gissel, Matthew T; Szuldrzynski, Konstanty; Zmudka, Krzysztof; Mann, Kenneth G: Factor XIa and tissue factor activity in patients with coronary artery disease
150
Zeymer, Uwe; Gitt, Anselm; Jünger, Claus; Bauer, Timm; Heer, Tobias; Koeth, Oliver; Wienbergen, Harm; Zahn, Ralf; Senges, Jochen: Efficacy and safety of enoxaparin in unselected patients with ST-segment elevation myocardial infarction
155
Zeymer, Uwe; Gitt, Anselm K; Jünger, Claus; Bauer, Timm; Koeth, Oliver; Heer, Tobias; Mark, Bernd; Zahn, Ralf; Gottwik, Martin; Senges, Jochen: Clopidogrel in addition to aspirin reduces in-hospital major cardiac and cerebrovascular events in unselected patients with acute ST segment elevation myocardial
161
Angiolillo, Dominick J; Bernardo, Esther; Palazuelos, Jorge; Desai, Bhaloo; Weisberg, Ian; Alfonso, Fernando; Guzman, Luis A; Hernández-Antolin, Rosana; Zenni, Martin Z; Macaya, Carlos; Fernandez-Ortiz, Antonio; Bass, Theodore A: Functional impact of high clopidogrel maintenance dosing in patients undergoing elective percutaneous coronary interventions
169
Shenhar-Tsarfaty, Shani; Assayag, Einor Ben; Bova, Irena; Shopin, Ludmila; Cohen, Michael; Berliner, Shlomo; Shapira, Itzhak; Bornstein, Natan M: Persistent hyperfibrinogenemia in acute ischemic stroke / transient ischemic attack (TIA)
174
Trenk, Dietmar; Hochholzer, Willibald; Frundi, Devine; Stratz, Christian; Valina, Christian M; Bestehorn, Hans-Peter; Büttner, Heinz Joachim; Neumann, Franz-Josef: Impact of cytochrome P450 3A4-metabolized statins on the antiplatelet effect of a 600-mg loading dose clopidogrel and on clinical outcome in patients undergoing elective coronary stent placement
182
Spring, Silviana; Simon, Roger; Loo, Bernd van der; Kovacevic, Tamara; Brockes, Christiane; Rousson, Valentin; Amann-Vesti, Beatrice; Koppensteiner, Renate: High-dose atorvastatin in peripheral arterial disease (PAD): Effect on endothelial function, intima-media-thickness and local progression of PAD

Animal Models

190
Schulz, Christian; Konrad, Ildiko; Sauer, Susanne; Orschiedt, Lena; Koellnberger, Maria; Lorenz, Reinhard; Walter, Ulrich; Massberg, Steffen: Effect of chronic treatment with acetylsalicylic acid and clopidogrel on atheroprogression and atherothrombosis in ApoE-deficient mice in vivo
196
Torzewski, Michael; Reifenberg, Kurt; Cheng, Fei; Wiese, Elena; Küpper, Ines; Crain, Jeanine; Lackner, Karl J; Bhakdi, Sucharit: No effect of C-reactive protein on early atherosclerosis in LDLR-/- / human C-reactive protein transgenic mice

New Technologies, Diagnostic Tools and Drugs

202
Constans, Joel; Salmi, Louis-Rachid; Sevestre-Pietri, Marie-Antoinette; Perusat, Sophie; Nguon, Monika; Degeilh, Maryse; Labarere, Jose; Gattolliat, Olivier; Boulon, Carine; Laroche, Jean-Pierre; Roux, Philippe Le; Pichot, Olivier; Quéré, Isabelle; Conri, Claude; Bosson, Jean-Luc: A clinical prediction score for upper extremity deep venous thrombosis
215
Jakubowski, Joseph A; Payne, Christopher D; Li, Ying G; Farid, Nagy A; Brandt, John T; Small, David S; Salazar, Daniel E; Winters, Kenneth J: A comparison of the antiplatelet effects of prasugrel and high-dose clopidogrel as assessed by VASP-phosphorylation and light transmission aggregometry
223
Couturaud, Francis; Duchemin, Jèrôme; Leroyer, Christophe; Delahousse, Bènèdicte; Abgrall, Jean François; Mottier, Dominique; for the Groupe d’Etude de la Thrombose de Bretagne Occidentale (G.E.T.B.O): Thrombin generation in first-degree relatives of patients with venous thromboembolism who have factor V Leiden
229
Gibson, Nadine S; Sohne, Maaike; Kruip, Marieke J. H. A; Tick, Lidwine W; Gerdes, Victor E; Bossuyt, Patrick M; Wells, Philip S; Buller, Harry R; the Christopher study investigators; on behalf of: Further validation and simplification of the Wells clinical decision rule in pulmonary embolism

New Technologies. Diagnostic Tools and Drugs

208
Lobo, Bob; Finch, Christopher; Howard, Amanda; Minhas, Sohail: Fondaparinux for the treatment of patients with acute heparininduced thrombocytopenia

Case Report

235
Blinc, Ales; Golli, Tanja; Vodnik, Alenka Cerar; Zver, Samo: Concurrent thalidomide and radiation therapy for extensive arterio-venous malformations