DOI: 10.1055/s-00000131

Synfacts

Issue 11 · Volume 10 · November 2014 DOI: 10.1055/s-004-27934

Synform

A143
Zanda, Matteo: SYNFORM ISSUE 2014/11

Synthesis of Natural Products and Potential Drugs

z1117
All PDFs of this category
1117
Syntheses of (+)-Flabellidine and (–)-Lycodine
1118
Synthesis of Fibrinolysis Inhibitor AZD6564
1119
Synthesis of a CETP Inhibitor
1120
Synthesis of (−)-Methyl Atisenoate and (−)-Isoatisine
1121
Formal Synthesis of Rosuvastatin and Pitavastatin
1122
Total Synthesis of Aspeverin
1123
Synthesis of (–)-Lepistine
1124
Synthesis of VX-787
1125
Synthesis of Δ12-Prostaglandin J3
1126
Total Synthesis of Gymnothelignan N
1127
Synthesis of (–)-Xanthatin
1128
Synthesis of SGLT-2 Inhibitor Empagliflozin
1129
Synthesis of Thrombin Inhibitor AZD8165

Synthesis of Heterocycles

z1131
All PDFs of this category
1131
Spirocyclic and Ring-Expanded Fused Pyrazoles
1132
Synthesis of Aminotriazoloazepinone-Containing Di- and Tripeptides
1133
N-Aryl Heterocycles by Catalytic Photoredox Olefin Hydroamination
1134
Synthesis of the SF5 Analogue of Umemoto Salt
1135
An Organocatalytic Cascade Route to Functionalized Azepines
1136
Iron-Catalyzed Synthesis of Difluoromethylsulfonylated Oxindoles
1137
Quinoxaline N-Oxides by Dehydrogenative N-Incorporation of Imines
1138
Synthesis of Spiroaminals by Au/Sc Relay Catalysis
1139
NHC-Promoted Annulation Approach to Pyranyl Aldehydes
1140
C-8 Alkylation and Alkynylation of Quinoline N-Oxides by Rhodium Catalysis
1141
Copper-Catalyzed Synthesis of Dibenzodiazepinones
1142
Copper-Catalyzed Synthesis of Sulfonylated Oxindoles
1143
Synthesis of Benzotriazoles from 2-(Arylamino)aryliminophosphoranes
1144
Synthesis of Heterocycles by Palladium-Catalyzed Intramolecular C–H Amination
1145
Three-Component Reaction Approach to Aminopyrazoles and Iminopyrimidines

Synthesis of Materials and Unnatural Products

z1147
All PDFs of this category
1147
A Starphene is Born: Largest and Most Soluble to Date
1148
Covalent Cage Construction via Alkyne Metathesis
1149
Every Cloud Has a Silver(I) or Tetramethylammonium Lining
1150
Iterative Benzannulation for Rapid Build-up of Congested Aromatic Systems
1151
Playing Dominoes with Palladium: Synthesis of Biaryl Tertiary Amines
1152
Rearrange Your Way to Tricyclic Heteroaromatics
1153
Taming the Wild Terminal Aryl Alkyne for High-Yield Cross-Metathesis
1154
Complex Polyphenylenes from Bromo-Oligophenylboronic Acids
1155
Platinum(II)-Catalyzed Synthesis of Substituted Azulenes
1156
The Road to Rotanes is Paved with Exocyclic Alkenes
1157
Synthetic Strategy Toward Enantiopure Helicene Quinones
1158
Nitrogen-Doped Zigzag-Edge Nanographenes

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z1159
All PDFs of this category
1159
Mannich–Cyclization Cascade Reaction Catalyzed by Squaramide/AgOAc
1160
Asymmetric Hydrogenation of Sterically Hindered Enones
1161
Asymmetric Synthesis of Tetrahydrofurans Bearing Multiple Stereocenters
1162
Ruthenium-Catalyzed Synthesis of Enantioenriched γ-Substituted Lactones
1163
Iridium-Mediated Asymmetric Synthesis of Branched Allylic Sulfilimines
1164
Diastereoselective Cyanation and Trifluoromethylation of Ketimines
1165
Palladium-Catalyzed Asymmetric Allyl–Aryl Cross-Coupling Using Allylboronates
1166
Synthesis of (+)-Discodermolide via Borylation
1167
Asymmetric Hydrogenation of α,β-Unsaturated Nitriles
1168
Stereoselective Synthesis of cis-4-Aryl-cyclopent-2-en-1-ols
1169
Enantioselective C–H Addition of Pyridines to Alkenes
1170
Palladium-Catalyzed Stereoselective Cascade Reaction for a Planar Core Structure
1171
Rhodium/Phosphoric Acid Co-Catalyzed Asymmetric Csp2–H Functionalization
1172
Ruthenium-Catalyzed Cylization of Aromatic Nitriles with Alkenes
1173
Pd/Cu-Catalyzed Alkynylative Ring Opening of Oxabenzonorbornadienes
1174
Diastereoselective Amination of Alcohols Catalyzed by Ruthenium
1175
Enantioselective Allyl–Allylsilane Cross-Coupling Catalyzed by Iridium
1176
Intramolecular Ruthenium-Mediated trans-Selective Silylvinylation of Alkynes
1177
Rhodium-Catalyzed Cyclopropanation of N-Enoxyphthalimides
1178
Synergistic Catalysis for Asymmetric Cascade Transformations
1179
Functionalized Azulenes via Rhodium-Mediated N-Sulfonylaminoalkenylation
1180
Rhodium-Catalyzed Asymmetric Synthesis of Tetrahydroquinolines
1181
Chiral Bicyclo[3,2,1]octanes via Domino Reaction
1182
Asymmetric aza-Henry Reaction Catalyzed by Copper
1183
Copper-Catalyzed Asymmetric Boron Conjugate Addition in Water
1184
Palladium-Catalyzed Stereospecific C-3 Arylation of Proline Derivatives
1185
Rhodium-Catalyzed Enantioselective Carbonyl–Ene Reaction
1186
Asymmetric Nickel-Catalyzed Synthesis of Spiro[isoxazolin-3,3′-oxindoles]
1187
Heterobimetallic Rare-Earth–Lithium Complexes for Asymmetric Epoxidations

Metal-Mediated Synthesis

z1189
All PDFs of this category
1189
Synthesis of 2,3-Disubstituted Indoles from Isatins
1190
γ-Selective Arylation of Zincated Boc-Allylamines
1191
Ketones from Carbon Dioxide and Organolithium or Grignard Reagents
1192
Carbolithiation of Chloro-Substituted Alkynes
1193
Zinc-Catalyzed Synthesis of Aryl Boronates
1194
Synthesis of Polysubstituted Phenanthridines
1195
Trifluoromethylthiolation of Alcohols
1196
Alkoxide-Promoted Deborylative Alkylation of Bis(boronates)
1197
Indium-Mediated Intramolecular Allenylation of N-tert-Butanesulfinyl Imines
1198
Copper-Mediated ortho-Nitration of Aromatic Amides
1199
Cross-Coupling of N-Tosylaziridines with Organozinc Reagents
1200
Nickel-Catalyzed Difluoroalkylation of Organoboronic Acids
1201
Cross-Coupling Reactions of Diazo Compounds and Vinylboronic Acids
1202
Copper(II)-Mediated Ortho C–H Alkynylation
1203
Asymmetric Arylation of Cyclic N-Sulfonyl Ketimines

Organo- and Biocatalysis

z1205
All PDFs of this category
1205
Organocatalytic Asymmetric Mannich Synthesis of α-Amino Esters
1206
ω-Transaminase-Catalyzed Reductive Amination of Ketones
1207
N-Heterocyclic Carbene Catalyzed Formal [3+2] Annulation of Enals
1208
Kinetic Resolution of Axially Chiral Diols and Amino Alcohols
1209
Kinetic Resolution of BINOL Derivative Catalyzed by Chiral DMAPs
1210
Enantioselective Formation of All-Carbon Quaternary Stereocenters
1211
Biocatalytic Oxidative Desymmetrization of Piperidine Carboxylates
1212
Disulfonimide-Catalyzed Enantioselective Torgov Cyclization
1213
Catalytic Asymmetric Synthesis of 4-Nitropyrazolidines
1214
Asymmetric Synthesis of Pyrrolines Using Bicyclic Phosphine Catalysts
1215
Enantioselective Route to Piperidines via Covalent Phosphoric Acid Catalysis
1216
Desymmetrization of 1,3-Diols via Oxidative Cleavage of Benzylidene Acetals

Polymer-Supported Synthesis

z1217
All PDFs of this category
1217
1,3-Addition of Silyl Enol Ethers to Nitrones Using Al-MCM-41
1218
Allylation of Imines and Aldehydes Using Pd-POMs
1219
An Organo Porous Polymer Catalyst for Asymmetric Alkylation with Et2Zn
1220
Selenophenes and Selanyl Selenophenes Using CuO Nanoparticles
1221
C–C Cross-Couplings Using Triazole Dendrimer Stabilized Pd Nanoparticles
1222
Co–Pd Magnetic Nanoparticle Catalyst for the Aerobic Oxidation of Alcohols
1223
Oxidation of Alcohols Using CoFe2O4@APTES@Ni(OH)2
1224
Direct Glycosylation with Sc(OTf)2-NSMP Catalyst in Water
1225
Polymer-Incarcerated Gold Nanocluster Catalysts for Oxidation
1226
Chemoselective Hydrogenation of Chloronitrobenzenes Using Pt/C
1227
Deoxygenation of Sulfoxides Using Ruthenium Nanoparticles Supported on TiO2
1228
O-Arylation of Phenols with Aryl Halides Using Cu/Nf–Graphene Nanoribbons
1229
The Michael Addition of Aldehydes to Nitroalkenes with Carrageenan/MNPs
1230
Solid-Phase Synthesis of 1,2,3-Triazoles Using 4,4′-Bismethoxybenzhydryl Azide
1231
C(sp)–C(sp) and C(sp)–C(sp2) Cross-Coupling with CuFe2O4 Nanoparticles