DOI: 10.1055/s-00000131

Synfacts

Issue 10 · Volume 9 · October 2013 DOI: 10.1055/s-003-25656

Synform

A120
Zanda, Matteo: SYNFORM ISSUE 2013/09

Synthesis of Natural Products and Potential Drugs

z1031
All PDFs of this category
1031
Synthesis of Viridicatumtoxin B
1032
Synthesis of (–)-Lyconadin C
1033
Synthesis of AMG 837
1034
Synthesis of Drimentines A, F, and G; and Indotertine A
1035
Synthesis of All Four Mefloquine Diastereoisomers
1036
Synthesis of Ezetimibe
1037
Synthesis of a β-Secretase Inhibitor
1038
Synthesis of a Selective Estrogen Receptor β Agonist
1039
Total Syntheses of Trichorabdal A and Longikaurin E
1040
Synthesis of ELND007
1041
Total Synthesis of (–)-Citrinadin A
1042
Total Synthesis of (+)-Citrinadin B
1043
Synthesis of (±)-Steviol and (±)-Isosteviol

Synthesis of Heterocycles

z1045
All PDFs of this category
1045
Biginelli Synthesis of Pyrimidones Using Terminal Alkenes as Precursors
1046
Synthesis of Isoxazolines and Pyrazolines via Radical C–H Oxidation
1047
Synthesis of 1-Aryl 1,2,4-Triazoles by a Three-Component Condensation
1048
Coumarin Synthesis by Carbonylation of 2-Hydroxystyrenes
1049
Synthesis of Pyrazolines via a Catalytic Asymmetric 1,3-Dipolar Cycloaddition
1050
Synthesis of Functionalized Cyclazines in One Pot Using Palladium Catalysis
1051
Carbamoylation–Bromolactamization Route to Five- and Six-Membered Lactams
1052
Palladium-Catalyzed Oxidative Annulation Route to Benzo[b]furans
1053
Regioselective Synthesis of 3,4,5- and 1,3,5-Trisubstituted Pyrazoles
1054
Oxidative Cyclization–Dehydrogenation Route to 2-Aminobenzothiazoles
1055
Palladium-Catalyzed Synthesis of 4-Aminophthalazinones
1056
Diarylpyridazines through Sequential Regioselective Suzuki Coupling
1057
Synthesis of 6H-Benzo[c]chromen-6-ones via C–H Activation–Lactonization
1058
Synthesis of Benzo[b]furans Using 2-(2-Hydroxyphenyl)acetonitriles

Synthesis of Materials and Unnatural Products

z1059
All PDFs of this category
1059
A New Monomer for High Molecular Weight Polyketals
1060
Polycyclic Aromatic Hydrocarbons From 1,1-Difluoroallenes
1061
A Versatile Method for Substituted Dibenzopentalenes
1062
Two Wrongs Make a Right in Tandem Metathesis Polymerization
1063
Poly(3-hexylthiophene) via Continuous-Flow Synthesis
1064
Regioselective C3-Alkenylation of Thiophene-2-carboxylic Acids
1065
An Alternative Entry to Unsymmetrical 1,3-Diynes
1066
Anthanthracene-Containing Molecular Belts
1067
Hydrogen-Bond-Assisted Macrocyclization
1068
A Pd–Cu–Ag Trimetallic System to Convert Indoles into Carbazoles
1069
Transition-Metal-Free 1,3-Alkynylation of Isoindoles
1070
Saddle-Up: peri-Substituted [8]Circulenes

Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions

z1071
All PDFs of this category
1071
Ligand Design for Iridium-Catalyzed Asymmetric Hydrogenation of Olefins
1072
Ruthenium-Catalyzed Z-Selective RO/CM and ROMP
1073
Ruthenium-Catalyzed Asymmetric, Z-Selective Ring Opening/Cross Metathesis
1074
A Novel Bifunctional Ligand–Metal Combination for Asymmetric Hydrogenation
1075
Hydrogenation of Tetrasubstituted Olefins Catalyzed by Iridium
1076
Ytterbium-Catalyzed Enantioselective Mannich Reaction of Malonates
1077
Copper-Catalyzed Conjugate Addition of Aryl- and Alkylaluminum Reagents
1078
Rhodium-Catalyzed Efficient Synthesis of Mixed 3,3′-Bisindoles
1079
Asymmetric Transfer Hydrogenation of Nitroalkenes by an Iridium Complex
1080
Asymmetric Carbonyl Allylation via Catalyic Generation of Allylcopper Intermediates
1081
Copper-Catalyzed Asymmetric Vinylogous Mannich-Type Reaction
1082
Copper-Catalyzed Asymmetric 1,4-Addition of Grignard Reagents to Chromones
1083
Copper-Catalyzed Asymmetric 1,4-Addition Reaction
1084
Copper-Catalyzed Asymmetric Aldehyde Difluoroalkylation
1085
Enantioselective Addition of Arylboronic Acids to Ketimines
1086
Gold-Catalyzed Synthesis of 3,4-Disubstituted Butyrolactams
1087
Gold- and Rhodium-Catalyzed Tandem Synthesis of β-Disubstituted Ketones
1088
Asymmetric Intramolecular N-Arylation meets Kinetic Resolution
1089
Rhodium(I)-Catalyzed Enantioselective 1,4-Addition of Aryl Boronic Acids to Enones
1090
Asymmetric Bromocyclization of Allenes Catalyzed by Gold
1091
Palladium-Catalyzed Decarboxylative Allylic Alkylation Reaction
1092
Ruthenium-Catalyzed Isomerization of Primary Allylic Alcohols into Aldehydes
1093
Chiral 1,5-Diols via Asymmetric Hydrogenation of δ-Keto Esters
1094
Gold-Catalyzed Enantioselective Synthesis of Cyclopentadienes
1095
Functionalized Dibenzazapinones via Pd-Catalyzed Asymmetric C−H Arylation
1096
Diastereoselective Povarov Reaction of Donor–Acceptor Cyclopropenes
1097
All-Carbon Quaternary Stereocenters via Iridium-Catalyzed Allylic Alkylation
1098
Rhodium-Catalyzed C–H Functionalization–Allene Cyclization
1099
Iridium-Catalyzed Amination of Unsymmetrical Allyl Carbonates
1100
Aldol-Type Reactions of Zinc Enolate Equivalents of Amides

Metal-Mediated Synthesis

z1101
All PDFs of this category
1101
Silver-Mediated Methoxycarbonyltetrafluoroethylation of Arenes
1102
Synthesis of Interrupted Fischer-Indole Intermediates via Oxyarylation
1103
Cobalt–NHC-Catalyzed ortho-Alkylation of Aromatic Imines with Alkyl Halides
1104
Multisubstituted Olefins via Chemoselective Cross-Coupling Sequences
1105
Enantioselective Allylic Substitution–Conjugate Addition
1106
Nickel-Catalyzed Cyclization/sp3–sp3 Cross-Coupling Cascade Reaction
1107
Remarkable Configurational Stability of Magnesiated Nitriles
1108
Synthesis of Tetrasubstituted Pyrroles from Terminal Alkynes and Imines
1109
Synthesis of tert-Alkylamines by Sequential Retro-Ene Arylation
1110
Chemoselective Iron-Catalyzed Alkylation of Dihaloaromatics
1111
Tetrasubstituted Olefin Synthesis via a Halogen-Induced 1,2-Silyl Migration
1112
One-Pot Asymmetric Allylation/Ring-Closing Metathesis Reactions
1113
Silver-Mediated Trifluoromethylation of Aryldiazonium Salts
1114
Haloboration of Internal Alkynes as a Route to Tetrasubstituted Alkenes
1115
Transition-Metal-Free Sonogashira-Type Cross-Couplings of Fluoroarenes

Organo- and Biocatalysis

z1117
All PDFs of this category
1117
NHC-Catalyzed Formal LUMO Activation of α,β-Unsaturated Esters
1118
Organocatalytic Site-Selective Phosphorylation of Teicoplanin
1119
Cyclopropenimine-Catalyzed Mannich Reaction
1120
Photoredox Organocatalytic α-Amination of Aldehydes
1121
NHC-Catalyzed Asymmetric Acylation of Diols and Amino Alcohols
1122
Oxidative Kinetic Resolution of Indolines by Transfer Hydrogenation to Imines
1123
Enantioselective Fluorination-Induced Wagner–Meerwein Rearrangement
1124
Enantioselective Silyl Protection of Alcohols by Two Lewis Basic Catalysts
1125
Diarylprolinol-Catalyzed Cross-Aldol Reaction with Alkynyl Aldehydes

Polymer-Supported Synthesis

z1127
All PDFs of this category
1127
Azidation of Arylboronic Acids in Water Catalyzed by Magnetic CuFe2O4 NPs
1128
Hydrogenation of Olefins Catalyzed by a Pt12-Cluster
1129
Aerobic Epoxidation with a Polyoxomolybdate Nanoball
1130
Oxidative Cross Double Carbonylation of Amines and Alcohols Using Pd/C
1131
Corriu−Kumada−Tamao Reaction Catalyzed by Polymer-Supported Nickel NPs
1132
Selenation of Aryl Halides and Styryl Bromides Using Cu-Al2O3
1133
Hydrophosphonylation of Aldehydes Catalyzed by Polystyryl-BEMP
1134
Reductive Amination with Nitroarenes Using a PdAg Nanocatalyst
1135
Asymmetric Michael Addition Using Polystyrene-Supported Squaramide
1136
A Polymeric Boron–Iridium Bimetallic Catalyst for the N-Alkylation of Amines
1137
Cp*Ru(II)/SiO2/γ-Fe2O3-Catalyzed Alkyne–Azide Cycloaddition
1138
Dehydrogenation of Alcohols with Ru/SrTiO3:Rh under Visible Light
1139
Pd/C-Catalyzed Suzuki–Miyaura Coupling

Erratum

1140
Sakai, T.; Soeta, T.; Endo, K.; Fujinami, S.; Ukaji, Y.: Asymmetric Strecker-Type Reaction of Nitrones Using Cyanohydrin