DOI : 10.1055/s-00000094

Zeitschrift für Gastroenterologie

Issue 01 · Volume 50 · January 2012 DOI: 10.1055/s-002-22742


28. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber
Hamburg, 27.–28. 1. 2012

Kongresspräsidentin: Prof. Dr. rer. nat. Gisa Tiegs

  • FV4_01
  • FV4_02
    Abdulkarim, M; Wiegard, C; Glaubke, C; Lohse, AW; Schramm, C; Weiler-Normann, C:

    Atypische Präsentation der Primär biliären Zirrhose bei Männern

  • FV4_03
    Frings, MK; Stabenow, D; Odenthal, M; Heikenwälder, M; Kashkar, H; Krönke, M; Knolle, PA:

    Viral infection sensitizes hepatocytes towards TNF-induced apoptosis

  • P4_01
    Abdullah, Z; Riethausen, K; Geiger, S; Muralev, E; Tribica, J; Knolle, P:

    Hepatic fibrosis attenuates virus-specific CD8 T cell immunity causing virus persistence

  • P4_02
    Albrecht, U; Kulawik, A; Raue, A; Timmer, J; Klingmüller, U; Häussinger, D; Bode, JG:

    Dynamic model of IL–6 and IL–1beta dependent signalling in primary murine hepatocytes

  • P4_03
    Allweiss, L; Lütgehetmann, M; Volz, T; Helbig, M; Lohse, AW; Petersen, J; Ma, H; Klumpp, K; Fletcher, S; Dandri, M:

    TREATMENT WITH PEGYLATED INTERFERON-ALPHA INDUCES SUSTAINED SUPPRESSION OF BOTH VIRUS REPLICATION AND ANTIGENEMIA IN HUMANIZED uPA/SCID MICE STABLY INFECTED WITH HBV

  • P4_04
    Amanzada, A; Lindhorst, A; Moriconi, F; Blaschke, M; Suermann, T; Mihm, S; Ramadori, G:

    Persistent HCV-infection and liver damage change vitamin-D-metabolism

  • P4_05
    Amanzada, A; Lindhorst, A; Moriconi, F; Blaschke, M; Wietzke-Braun, P; Suermann, T; Mihm, S; Ramadori, G:

    IL28B allelic variation but not polymorphism of CYP27B1 or genotype of HCV is associated with spontaneous elimination of HCV-infection

  • P4_06
  • P4_07
  • P4_08
    Bauer, T; Kutscher, S; Allgayer, S; Kittner, J; Schuchmann, M; Galle, PR; Sprinzl, MF; Protzer, U; Protzer, U:

    Add-on of pegylated interferon alpha–2a (PEG-IFN) triggers antigen-independent TNF-alpha production by CD4+ T cells in patients with pretreated chronic hepatitis B

  • P4_09
    Beisel, C; Heuer, M; Schulze zur Wiesch, J; Zoufaly, A; Jochum, J; van Lunzen, J:

    Hepatitis C Therapie in HCV/HIV koinfizierten Patienten – eine monozentrische Kohortenstudie

  • P4_10
    Beisel, C; Tóth, I; Scheurich, C; Matzat, V; Kummer, S; Lüth, S; van Lunzen, J; Hartjen, P; Lohse, A; Schulze zur Wiesch, J:

    Charakterisierung von B – Zell – Aktivierungs- und Koinhibitionsmarkern in Patienten mit chronischen Virusinfektionen (HBV; HCV)

  • P4_11
  • P4_12
    Böttcher, JP; Stabenow, D; Debey-Pascher, S; Staratschek-Jox, A; Grell, J; Höchst, B; Limmer, A; Atreya, I; Neurath, MF; Hegenbarth, S; Schmitt, E; Busch, DH; van Endert, P; Kolanus, W; Kurts, C; Schultze, JL; Diehl, L; Knolle, PA:

    Antigen cross-presentation in the liver generates protective memory CD8+ T cells in the absence of inflammation

  • P4_13
  • P4_14
  • P4_15
  • P4_16
  • P4_17
    Dorn, C; Jilg, W; Heilmann, J; Hellerbrand, C:

    Xanthohumol inhibits hepatitis B virus replication in vitro

  • P4_18
  • P4_19
    Eisenhardt, M; Glässner, A; Krämer, B; Sibbing, B; Sauerbruch, T; Spengler, U; Nattermann, J:

    Gestörte Funktion von CD56high CXCR3(+) NK Zellen als möglicher neuer Mechanismus der HCV-assoziierten Leberfibrose

  • P4_20
  • P4_21
    Fabian, J; Urban, S; Dooley, S; Meindl-Beinker, NM:

    Impact of HBV infection on TGF-β signaling in primary human hepatocytes

  • P4_22
  • P4_23
    Gane, E; Deray, G; Piratvisuth, T; Chan, HLY; Jia, J; Ren, H; Rasenack, J; Manns, M; Amarapurkar, D; Dong, Y; Trylesinski, A:

    Telbivudine treatment improves renal function of Chronic Hepatitis B (CHB) patients

  • P4_24
    Glässner, A; Eisenhardt, M; Krämer, B; Wolter, F; Kokordelis, P; Sibbing, B; Sauerbruch, T; Spengler, U; Nattermann, J:

    HCV-vermittelte Blockierung der IL–2 Sekretion von CD4(+) T-Zellen hemmt die anti-fibrotische Aktivität von NK-Zellen

  • P4_25
  • P4_26
    Höchst, B; Schildberg, FA; Huss, S; Metzger, C; Knoblich, A; Schneider, B; Pantelis, D; Kalff, J; Knolle, P; Diehl, L:

    Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance to systemic circulating carcinoembryonic antigen: A new mechanism of Tumour-immune-Suppression

  • P4_27
  • P4_28
  • P4_29
    Hüppe, D; Mauss, S; Lutz, T; Schuchmann, M; Moog, G; Schober, A; Heyne, R; John, C; Schiffelholz, W; Eisenbach, C; Teuber, G; Baumgarten, A; Schott, E; Alshuth, U; Buggisch, P:

    Confirmation of high SVR rates after shortening duration of treatment with Peginterferon alfa–2a (PEG) and Ribavirin (RBV) in Chronic Hepatitis C (CHC) Patients with RVR in Real Life

  • P4_30
  • P4_31
    Kant, J; Möller, B; Heyne, R; Herber, A; Mössner, J; Berg, T; Wiegand, J:

    Evaluation of a rapid on-site anti-HCV test as screening tool for hepatitis C infection

  • P4_32
  • P4_33
  • P4_34
    Krämer, B; Körner, C; Eisenhardt, M; Glässner, A; Zwank, C; Sibbing, B; Wolter, F; Kokordelis, P; Sauerbruch, T; Spengler, U; Nattermann, J:

    Der NKp46-Rezeptor ist an der Regulation der anti-fibrotischen Aktivität von NK Zellen beteiligt

  • P4_35
    Langhans, B; Louis, M; Hüneburg, R; Oldenburg, J; Schultze, JL; Sauerbruch, T; Spengler, U:

    Adaptive CD4+ regulatorische T-Zellen regulieren die Fibrogenese durch Produktion von IL–8 bei chronischer Hepatitis C

  • P4_36
  • P4_37
    Lütgehetmann, M; M´Barek, M; Volz, T; Allweiss, L; Helbig, M; Alexandrov, A; Lohse, AW; Petersen, J; Urban, S; Dandri, M:

    THE ENTRY INHIBITOR MYRCLUDEX-B EFFICIENTLY BLOCKS VIRAL SPREADING IN VIVO IN HUMAN LIVER CHIMERIC uPA/ SCID MICE PREVIOUSLY INFECTED WITH HEPATITIS B VIRUS

  • P4_38
    Mauss, S; Hüppe, D; Lutz, T; Schober, A; Moog, G; Hey, KH; Schiffelholz, W; Teuber, G; Baumgarten, A; Schmidt, W; Stoehr, A; Waizmann, M; Isernhagen, K; Alshuth, U; Buggisch, P:

    Comparison of therapy outcome of patients with drug addiction (DA) versus patients with former iv drug use (IVDU) treated with Peginterferon alfa–2a/Ribavirin in real life setting

  • P4_39
  • P4_40
    Peiseler, M; Sebode, M; Katt, J; Franke, B; Wortmann, F; Quaas, A; Baron, U; Lohse, AW; Sobottka, I; Wiegard, C; Weiler-Normann, C; Herkel, J; Schramm, C:

    Patienten mit Primär Sklerosierender Cholangitis weisen ein gestörtes Gleichgewicht zwischen Foxp3+ regulatorischen T-Zellen und proinflammatorischen Th17 Zellen auf

  • P4_41
    Pischke, S; Horn-Wichmann, R; Ernst, D; Meyer, BG; Raupach, R; Ahrenstorf, G; Schmidt, RE; Manns, MP; Witte, T; Wedemeyer, H:

    Chronic hepatitis E in patients with CVID in Germany?

  • P4_42
    Real, CI; Bröring, R; John, M; Jahn-Hofmann, K; Ickenstein, L; Kleinehr, K; Gerken, G; Schlaak, JF:

    In vivo treatment with nanolipid-formulated siRNAs targeting ISG15 leads to enhanced responsiveness to interferon in primary hepatocytes

  • P4_43
  • P4_44
  • P4_45
    Röder, C; Jordan, S; Hoepner, L; Pudelski, N; Supplieth, M; Lohse, AW; Schulze zur Wiesch, J; Lüth, S:

    Chronische Hepatitis C Infektion: Herausforderung Alter

  • P4_46
    Roos, K; Haid, S; Herbst, A; Stremmel, W; Pietschmann, T; Müller, M:

    ROLE OF TUMOR SUPPRESSORS P53 AND P73 IN THE CELLULAR DEFENCE AGAINST HEPATITIS C VIRUS

  • P4_47
    Scheurich, C; Tóth, I; Matzat, V; Kummer, S; Polywka, S; Meyer, T; Eiermann, T; Lohse, AW; Hartjen, P; van Lunzen, J; Schulze zur Wiesch, J:

    Fine Characterization and Determination of Cross-Reactivity of HCV-specific CD4+ T Cell Epitopes

  • P4_48
    Schildberg, F; Höchst, B; Wojtalla, A; Siegmund, SV; Endl, E; Diehl, L; Abdullah, Z; Kurts, C; Knolle, PA:

    Hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism

  • P4_49
  • P4_50
    Schuchmann, M; Kittner, JM; Schlaak, JF; Klaas, D; Eisenbach, C; Berg, T; Trautwein, C; Günther, R; Zeuzem, S; Goesseringer, R; Ehrlich, A; Neumann, K; Wachtlin, D; Boecher, WO; Galle, PR:

    All-trans retinoic acid co-administered with pegylated interferon and ribavirin does not influence viral kinetics in hepatitis C infected patients with previous non-response: Results of the ATRACTION study

  • P4_51
    Sebode, M; Wiegard, C; Lohse, AW; Schramm, C; Weiler-Normann, C; Herkel, J:

    IFN-gamma und IL–17 Produktion durch SepSecS-reaktive T Zellen aus Patienten mit Autoimmuner Hepatitis

  • P4_52
    Sibbing, B; Boesecke, C; Kokordelis, P; Baumgarten, A; Ingiliz, P; Mauss, S; Krämer, B; Eisenhardt, M; Glässner, A; Naumann, U; Söhne, J; Sauerbruch, T; Rockstroh, J; Spengler, U; Nattermann, J:

    Der CYP27B1–1260 Promoter Polymorphismus rs120877012 ist bei HCV/HIV koinfizierten Patienten signifikant mit einem Ansprechen auf die Therapie der Hepatitis C Erkrankung (SVR) assoziiert

  • P4_53
  • P4_54
    Stiefel, J; Churin, Y; Roderfeld, M; Kopsch, K; Glebe, D; Roeb, E:

    Knochenmarktransplantation in HBV-transgenen Mäusen aggraviert die hepatische Fibrose

  • P4_55
    Suneetha, PV; Pischke, S; Schlaphoff, V; Grabowski, J; Fytili, P; Gronert, A; Bremer, B; Markova, A; Jaroszewicz, J; Bara, CL; Manns, MP; Cornberg, M; Wedemeyer, H:

    HEV-specific T-cell responses are associated with control of HEV infection

  • P4_56
    Tóth, I; Le, AQ; Hartjen, P; Thomssen, A; Beisel, C; Scheurich, C; Matzat, V; Kummer, S; Polywka, S; Frenzel, C; Lohse, AW; Lüth, S; van Lunzen, J; Schulze zur Wiesch, J:

    Downregulation of CD73 surface expression in regulatory as well as effector T cells in chronic HCV infection

  • P4_57
  • P4_58
    van Heeswijk, R; Boogaerts, G; De Paepe, E; Vangeneugden, T; De Backer, K:

    Bioavailability of the HCV NS3/4A Protease Inhibitor Telaprevir–Effect of Different Types of Food

  • P4_59
  • P4_60
    Volz, T; Lütgehetmann, M; Allweiss, L; Lohse, AW; Petersen, J; Dandri, M:

    PRETREATMENT OF HUMANIZED uPA/SCID MICE WITH INTERFERON ALPHA STRONGLY INHIBITS THE ESTABLISHMENT OF HBV INFECTION

  • P4_61
    Von Hahn, T; Schiene-Fischer, C; Steinmann, E; Strassburg, CP; Wedemeyer, H; Sarrazin, C; Müller, T; Berg, T; Manns, MP; Pietschmann, T; Ciesek, S:

    Variants in the human PPIA gene render host cells refractory to hepatitis C virus infection by destabilization of the essential host factor cyclophilin A

  • P4_62
  • P4_63
  • P4_64
  • P4_65
    Witthöft, T; Buggisch, P; Hüppe, D; Heyne, R; John, C; Möller, B; Moog, G; Schober, A; Schiffelholz, W; Baumgarten, A; Teuber, G; Lutz, T; Stoehr, A; Alshuth, U; Mauss, S:

    The Role of Weight Loss (WL) as On-Tretament Predictive Factor for SVR in the Treatment of Chronic Hepatitis C (CHC) Patients with Peginterferon alfa–2A (PEG) and Ribavirin (RBV)

  • P4_66
    Wüstenberg, A; Keller, AD; Lehmann, E; Sirma, H; Bartenschlager, R; Lohmann, V; Loscher, C; Dandri, M; Tiegs, G; Sass, G:

    Induction of heme oxygenase 1 by HMG-CoA-Reductase inhibitors interferes with HCV replication

  • P4_67