Summary
Objective:
It was the objective of this study to assess the impact of applying various record
linkage methods to one of the most important outcome measures in oncological epidemiology,
namely survival rates.
Methods:
To assess the life status of patients, incidence data published by the Cancer Registry
of Tyrol were analyzed with three routinely used methods of record linkage for incidence
and mortality data. Of these methods, two were deterministic and the third a probabilistic
method developed by the Cancer Registry of Tyrol. We studied the impact of record
linkage methods on a simple measure (mortality rate) and a more complex measure (relative
survival rate). The analysis was based on the published incidence data for Tyrol for
the years 1992 to 1996. Results of deterministic record linkage methodswere simulated.
Results:
The error rates for simple mortality rate and relative survival rate are considerable.
For the first deterministic record linkage method, relative differences in mortality
rate range from 11.9% to 14.8% (men) and 24.5% to 28.2% (women) and relative differences
in relative five-year survival from 11.4% to 16.3% (men) and from 19.3% to 26.4% (women).
For the second deterministic record linkage method, relative differences in mortality
rate range from 4.8% to 5.9% (men) and from 4.9% to 7.4% (women), while relative differences
in relative five-year survival range from 5.1% to 7.0% (men) and from 4.4% to 6.1%
(women).
Conclusions:
Our study shows that in order to calculate valid mortality and survival rates a probabilistic
method of record linkage must be applied.
Keywords
Record linkage - survival analysis - relative survival rate - mortality rate
