Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2008(9): 0950-0950
DOI: 10.1055/s-2008-1078638
DOI: 10.1055/s-2008-1078638
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag
Stuttgart ˙ New York
Enantioselective Sc(III)-Catalyzed Direct Allylation of Aldimines
X. Li, X. Liu, Y. Fu, L. Wang, L. Zhou, X. Feng*
Sichuan University, Chengdu, P. R. of China
Further Information
Publication History
Publication Date:
22 August 2008 (online)

Significance
The efficient catalytic asymmetric three-component allylation of aldimines is reported. The resulting optically active homoallylic amines are versatile intermediates in the organic synthesis and are obtained in high yield with excellent enantioselectivity under mild conditions. This paper builds on previous work in the field pioneered by Mosset, Wips, and Kobayashi (e.g., see: B. Choucair, H. Léon, M.-A. Miré, C. Lebreton, P. Mosset Org. Lett. 2000, 2, 1851).