PDF herunterladen
Synfacts 2008(6): 0620-0620  
DOI: 10.1055/s-2008-1078395
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York

Pd(II)-Catalyzed Cyclization of Allenyl Aldeydes with Arylboronic Acids

Contributor(s): Mark Lautens, Valentina Aureggi
H. Tsukamoto*, T. Matsumoto, Y. Kondo
Tohoku University, Sendai, Japan
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
21. Mai 2008 (online)

   Lizenzen und Reprints

Significance

The development of a Pd-catalyzed enantioselective cyclization of allenyl aldehydes with arylboronic acids is reported. The cis-cyclic homoallylic alcohols are obtained in good yields with excellent enantio- and diastereoselectivities.