Abstract
Acute aortic dissection is a life-threatening cardiovascular disease associated
with high morbidity and mortality. Introduction of newer imaging modalities and
therapeutic strategies have shown potential to improve diagnosis and management.
The International Registry of Acute Aortic Dissection (IRAD) was established in
1996 to assess current-day profiles and outcomes of this medical emergency. Analysis
from this on-going multinational database has contributed to a better understanding
of clinical presentation and prognosis in patients with acute aortic dissection.
Simple risk prediction tools are now available allowing accurate estimation of
a patients in-hospital risk using readily available clinical information at time
of presentation. Like for other cardiovascular diseases, such tools can be used
for educating patients about their individual risk and in clinical research for
risk adjustment while comparing outcomes of different therapeutic approaches.
The present article summarizes the most striking insights from IRAD spanning more
than 10 years of clinical research.
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Stephan Kische
Universitätsklinik Rostock
Klinik für Innere Medizin
Abteilung Kardiologie
Ernst-Heydemann-Str. 6
18057 Rostock
Email: stephankische@gmx.de
