Kelle H. Moley, M.D.

The effect of culturing and handling of oocytes and early embryos is an important research as well as clinical problem. We have only begun to understand these perturbations on the long-term consequences on offspring. In this issue, Dr. Kelle H. Moley will serve as Guest Editor of an entire issue of Seminars in Reproductive Medicine on this subject.

Dr. Moley is Professor and Vice Chair of Obstetrics and Gynecology and Director of the Division of Basic Science Research in the Department at Washington University School of Medicine. She is considered an international expert in the field of glucose transporter biology, and highly regarded for her work in preimplantation embryogenesis and implantation in mammalian models of maternal metabolic diseases. She is an Alpha Omega Alpha graduate of Yale University School of Medicine, and completed her obstetrics and gynecology residency training, and reproductive endocrinology and infertility fellowship training at Washington University School of Medicine/Barnes Hospital. She is board certified in obstetrics and gynecology and reproductive endocrinology and infertility. Dr. Moley did her postdoctoral training in the laboratory of Dr. Oliver Lowry in the Department of Pharmacology, and Dr. Mike Mueckler in the Department of Cell Biology and Physiology, both at Washington University. During this time, she began her studies of glucose utilization in the murine pre-implantation embryo, and the effects of maternal diabetes and hyperinsulinemia on embryo physiology. To complete this work, she obtained a K12 training grant or Reproductive Scientist Development Program Research Award, funded by the National Institute of Child Health and Development, and the Association of Professors of Gynecology and Obstetrics. Dr. Moley joined the faculty of Washington University as assistant professor of OB/GYN, and Cell Biology and Physiology in 1999. In 2003, she was promoted to associate professor in each of these departments. In 2006, she was named Vice Chair of Obstetrics and Gynecology and Director of the Division of Basic Science Research. She was also promoted to professor in 2006.

Dr. Moley serves key leadership roles at the University as well as nationally. Kelle Moley is an active member of the Society for Gynecologic Investigation (Program Chair, 2007), the Society for the Study of Reproduction (Chair of the Clinical Outreach Committee), the Society of Reproductive Endocrinology and Infertility (representative to the American Board of Obstetrics and Gynecology), currently serves on the Board of Directors of Frontiers in Reproduction, and is one of six associate editors of the American Journal of Physiology-Endocrinology and Metabolism. Dr. Moley also serves as Fellowship Director of the Reproductive Endocrinology and Infertility Fellowship Program at Washington University School of Medicine. Dr. Moley serves as co-principal investigator on a T32 in Reproductive Sciences, held by the OB/GYN Department. She also sits on the Washington University Faculty Senate Council and is Chair of the Benefits Committee. She is a member of the Steering Committee of Developmental Biology, and is a member of the Admissions Committee for the Division of Biomedical and Biophysical Studies (the graduate program at Washington University). Dr. Moley is also on the Steering Committee of the Markey Pathway for biomedical training of PhD students and serves as Director of the Clinical Mentorship Program.

Dr. Moley has recruited several investigators and authors to develop what we believe will be a very important, up-to-date reference on oocyte and preimplantation embryo perturbations and the effects on offspring and embryo outcomes.