Zusammenfassung
Herz-Kreislauf-Erkrankungen können die Lebensqualität frühzeitig deutlich einschränken
und stellen nach wie vor die häufigste Todesursache dar. Zahlreiche Veröffentlichungen,
darunter eine Reihe eindrucksvoller klinischer Studien, sind in den letzten Jahren
über den Granatapfel und seine herausragenden protektiven und ernährungstherapeutischen
Wirkungen auf das Herz-Kreislauf-System erschienen. Über verschiedenste zellregulatorische,
antiinflammatorische und antioxidative Effekte wirken die natürlichen Pflanzenstoffe
des Granatapfels der Pathogenese der Arteriosklerose entgegen. So vermochte der
auch für Diabetiker gesunde Saft in einer Reihe klinischer Studien deutlich
die Myokarddurchblutung bei KHK-Patienten zu verbessern und arteriosklerotische
Ablagerungen in der Karotis zu reduzieren.
Die außerordentliche antioxidative Kraft von Granatapfelsaft in vitro bestätigt
sich in einer deutlichen Steigerung des Gesamt-Antioxidanzien-Status (TAS) beim
Menschen. Granatapfelsaft und fermentierte Essenzen modulieren Entzündungsprozesse.
Hierbei dürfte die Aktivierungshemmung von NF-kappa-B, die in neun Studien nachgewiesen
wurde, eine zentrale Rolle spielen.
Abstract
Cardiovascular diseases can prematurely limit the quality of life and are still
the major cause of death. In recent years numerous research data, amongst them
remarkable clinical studies, have been published on pomegranate and its protective
and nutritionally therapeutic effects on the cardiovascular system. Via diverse
cell regulatory, anti-inflammatory and anti-oxidative pathways, the natural plant
substances of pomegranates prevent and counteract the pathogenesis of arteriosclerosis.
In a couple of clinical studies the juice that has been shown to be also beneficial
for diabetics, significantly improved the myocardiac perfusion of patients with
cardiovascular disease and reduced arteriosclerotic lesions of the carotis. The
exceptional anti-oxidative power of pomegranate juice in vitro has been confirmed
in humans in a significant increase of the total antioxidant status (TAS). Pomegranate
juice and fermented essences modulate inflammatory processes. The blockage of
the activation of NF-kappa-B which has been shown in 8 studies may play a central
role therein.
Schlüsselwörter
Granatapfel - Arteriosklerose - Immunmodulation - Antioxidans
Keywords
Pomegranate - arteriosclerosis - immune modulation - antioxidant
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