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Synfacts 2007(7): 0735-0735
DOI: 10.1055/s-2007-968615
DOI: 10.1055/s-2007-968615
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New YorkAsymmetric Imine Hydrogenation with Palladium Complexes
Y.-Q. Wang, S.-M. Lu, Y.-G. Zhou*
Dalian Institute of Chemical Physics and Shanghai Institute of Organic Chemistry, P. R. of China
Further Information
Publication History
Publication Date:
22 June 2007 (online)
Significance
The asymmetric hydrogenation of imines represents a potentially powerful method for generating chiral amines for possible use in preparing biologically active compounds. This substrate class remains a challenging target for many transition-metal catalysts developed so far.