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Planta Med 1995; 61(6): 502-504
DOI: 10.1055/s-2006-959357
Papers

© Georg Thieme Verlag Stuttgart · New York

Anti-Inflammatory Activity of Flavonol Glycosides from Erythrospermum monticolum Depending on Single or Repeated Local TPA Administration

Maria del Carmen Recio1 , Rosa Maria Giner1 , S. Máñez1 , Amparo Talens1 , Laura Cubells1 , J. Gueho2 , H. R. Julien2 , K. Hostettmann3 , J. L. Rios1
  • 1Departament de Farmacologia, Facultat de Farmàcia, Universitat de València, Avda. Vicent Andrés Estellés s/n, E-46100 Burjassot, València, Spain
  • 2Mauritius Sugar Industry Research Institute, Le Réduit, Mauritius
  • 3Institut de Pharmacognosie et Phytochimie, Université de Lausanne, CH-1015 Lausanne-Dorigny, Switzerland
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Publication History

1995

1995

Publication Date:
04 January 2007 (online)

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Corrected by:

ErratumPlanta Med 1996; 62(01): 96-96
DOI: 10.1055/s-2006-957825

Abstract

Two anti-inflammatory principles were isolated from the methanol extract of the leaves of Erythrospermum monticolum (Flacourtiaceae). The isolation was based on a guided bioassay of the inhibitory activity on TPA-induced ear edema in mice. These compounds were identified as quercetin 3-O-xylosyl(1→2) rhamnoside and quercetin 3-O-rhamnoside. In addition, their effects on a chronic topic inflammation model were evaluated.

Key words

Erythrospermum monticolum - Flacourtiaceae - flavonoids - quercetin 3-O-xylosyl(1→2)rhamnoside - quercetin 3-O-rhamnoside - in vivo anti-inflammatory activity