Clin Colon Rectal Surg 2006; 19(4): 195-206
DOI: 10.1055/s-2006-956440
Copyright © 2006 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Reoperative Inflammatory Bowel Disease Surgery

Rowena L. Ramirez1 , Phillip Fleshner1
  • 1Division of Colorectal Surgery, Cedars-Sinai Medical Center, Los Angeles, California
Further Information

Publication History

Publication Date:
24 November 2006 (online)

ABSTRACT

With the advent of restorative proctocolectomy or ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC), not only has there been potential for cure of UC but also patients have enjoyed marked improvements in bowel function, continence, and quality of life. However, IPAA can be complicated by postoperative small bowel obstruction, disease recurrence, and pouch failure secondary to pelvic sepsis, pouch dysfunction, mucosal inflammation, and neoplastic transformation. These may necessitate emergent or expeditious elective reoperation to salvage the pouch and preserve adequate function. Local, transanal, and transabdominal approaches to IPAA salvage are described, and their indications, outcomes, and the clinical parameters that affect the need for salvage are discussed. Pouch excision for failed salvage reoperation is reviewed as well. Relaparotomy is also frequently required for recurrent Crohn's disease (CD), especially given the nature of this as yet incurable illness. Risk factors for CD recurrence are examined, and the various surgical options and margins of resection are evaluated with a focus on bowel-sparing policy. Stricturoplasty, its outcomes, and its importance in recurrent disease are discussed, and segmental resection is compared with more extensive procedures such as total colectomy with ileorectal anastomosis. Lastly, laparoscopy is addressed with respect to its long-term outcomes, effect on surgical recurrence, and its application in the management of recurrent CD.

REFERENCES

  • 1 Corman M. Colon and Rectal Surgery. 5th ed. Philadelphia; Lippincott, Williams, & Wilkins 2004: 1319-1535
  • 2 Penner R, Madsen K, Fedorak R. Postoperative Crohn's disease.  Inflamm Bowel Dis. 2005;  11 765-777
  • 3 Fazio V W, Ziv Y, Church J M et al.. Ileal pouch anal anastomosis complications and function in 1005 patients.  Ann Surg. 1995;  222 120-127
  • 4 MacLean A, Cohen Z, MacRae H et al.. Risk of small bowel obstruction after the ileal pouch-anal anastomosis.  Ann Surg. 2002;  235 200-206
  • 5 Francois Y, Dozois R R, Kelly K A et al.. Small intestinal obstruction complicating ileal pouch-anal anastomosis.  Ann Surg. 1989;  209 46-50
  • 6 Becker J M, Dayton M T, Fazio V W et al.. Prevention of post-operative abdominal adhesions by a sodium hyaluronate-based bioresorbable membrane: a prospective, randomized, double-blind multicenter study.  J Am Coll Surg. 1996;  183 297-306
  • 7 Kelly K A. Anal sphincter-saving operations for chronic ulcerative colitis.  Am J Surg. 1992;  163 5-11
  • 8 Becker J M. Ileal pouch-anal anastomosis: current status and controversies.  Surgery. 1993;  113 599-602
  • 9 Gemlo B T, Wong W D, Rothenberger D A et al.. Ileal pouch-anal anastomosis-patterns of failure.  Arch Surg. 1992;  127 784-787
  • 10 Korsgen S, Keighley M R. Causes of failure and life expectancy of the ileoanal pouch.  Int J Colorectal Dis. 1997;  12 4-8
  • 11 Bullard K M, Madoff R D, Gemlo B T. Is ileoanal pouch function stable with time? Results of a prospective audit.  Dis Colon Rectum. 2002;  45 299-304
  • 12 Meagher A P, Farouk R, Dozois R R, Kelly K A, Pemberton J H. J ileal pouch-anal anastomosis for chronic ulcerative colitis: complications and outcome in 1310 patients.  Br J Surg. 1998;  85 800-803
  • 13 Tulchinsky H, Cohen C RG, Nicholls R J. Salvage surgery after restorative proctocolectomy.  Br J Surg. 2003;  90 909-921
  • 14 Tulchinsky H, Hawley P, Nicholls J. Long-term failure after restorative proctocolectomy for ulcerative colitis.  Ann Surg. 2003;  238 229-234
  • 15 Becker J M, Raymond J L. Ileal pouch-anal anastomosis: a single surgeon's experience with 100 consecutive cases.  Ann Surg. 1986;  204 375-383
  • 16 Sandborn W J. Pouchitis following ileal pouch-anal anastomosis: definition, pathogenesis, and treatment.  Gastroenterology. 1994;  107 1856-1860
  • 17 Tekkis P P, Heriot A G, Smith J J, Das P, Canero A, Nicholls R J. Long-term results of abdominal salvage surgery following restorative proctocolectomy.  Br J Surg. 2006;  93 231-237
  • 18 Belliveau P, Trudel J, Vasilevsky C A et al.. Ileoanal anastomosis with reservoirs: complications and long-term results.  Can J Surg. 1999;  42 345-352
  • 19 Heuschen U A, Allenmeyer E H, Hinz U, Lucas M, Herfarth C, Heuschen G. Outcome after septic complications in J pouch procedures.  Br J Surg. 2002;  89 194-200
  • 20 Dayton M T, Larsen K P. Outcome of pouch-related complications after ileal pouch-anal anastomosis.  Am J Surg. 1997;  174 728-732
  • 21 Dehni N, Remacle G, Dozois R, Banchini F, Tiret E, Parc R. Salvage reoperation for complications after ileal pouch-anal anastomosis.  Br J Surg. 2005;  92 748-753
  • 22 Ziv Y, Fazio V W, Church J M, Lavery I C, King T M, Ambrosetti P. Stapled ileal pouch anal anastomoses are safer than hand-sewn anastomoses in patients with ulcerative colitis.  Am J Surg. 1996;  171 320-323
  • 23 Lee P Y, Fazio V W, Church J M, Hull T L, Eu K W, Lavery I C. Vaginal fistula following restorative proctocolectomy.  Dis Colon Rectum. 1997;  40 752-759
  • 24 Lindquist K, Nilsell K, Liljeqvist L. Cuff abscesses and ileoanal anastomotic separations in pelvic pouch surgery-an analysis of possible etiologic factors.  Dis Colon Rectum. 1987;  30 355-359
  • 25 Fazio V W, Wu J S, Lavery I C. Repeat ileal pouch-anal anastomosis to salvage septic complications of pelvic pouches: clinical outcome and quality of life assessment.  Ann Surg. 1998;  228 588-597
  • 26 Baixauli J, Delaney C, Wu J S et al.. Functional outcome and quality of life after repeat ileal pouch-anal anastomosis for complications of ileoanal surgery.  Dis Colon Rectum. 2004;  47 2-11
  • 27 Whitlow C B, Opelka F G, Gathright Jr J B, Beck D E. Treatment of colorectal and ileoanal anastomotic sinuses.  Dis Colon Rectum. 1997;  40 760-763
  • 28 Williamson M E, Lewis W G, Sagar P M, Hodlsworth P J, Johnston D. One stage restorative proctocolectomy without temporary ileostomy for ulcerative colitis: a note of caution.  Dis Colon Rectum. 1997;  40 1019-1022
  • 29 MacLean A R, O'Connor B, Parkes R, Cohen Z, McLeod R S. Reconstructive surgery for failed ileal pouch-anal anastomosis: a viable surgical option with acceptable results.  Dis Colon Rectum. 2002;  45 880-886
  • 30 Dehni N, Cunningham C, Parc R. Use of a jejunal pouch with ileal interposition in salvage surgery after restorative proctocolectomy.  Dis Colon Rectum. 1998;  41 1587-1589
  • 31 Loriau J, Benoist A, Panis Y, Joly F, Messing B, Valleur P. Salvage of ileal pouch-anal anastomosis by a reversed jejunal segment.  Surgery. 2005;  137 111-113
  • 32 Galandiuk S, Scott N A, Dozois R R et al.. Ileal pouch-anal anastomosis. Reoperation for pouch-related complications.  Ann Surg. 1990;  212 446-454
  • 33 Sagar P M, Dozois R R, Wolff B G, Kelly K A. Disconnection, pouch revision, and reconnection of the ileal pouch-anal anastomosis.  Br J Surg. 1996;  83 1401-1405
  • 34 Korsgen S, Nikteas N, Ogunbiyi O A, Keighley M R. Results from pouch salvage.  Br J Surg. 1996;  83 372-374
  • 35 Ogunbiyi O A, Korsgen S, Keighley M R. Pouch salvage. Long-term outcome.  Dis Colon Rectum. 1997;  40 548-552
  • 36 Paye F, Penna C, Chiche L, Tiret A, Frileux P, Parc R. Pouch-related fistula following restorative proctocolectomy.  Br J Surg. 1996;  83 1574-1577
  • 37 Ozuner G, Hull T, Lee P, Fazio V W. What happens to a pelvic pouch when a fistula develops?.  Dis Colon Rectum. 1997;  40 543-547
  • 38 Cohen Z, Smith D, McLeod R. Reconstructive surgery for pelvic pouches.  World J Surg. 1998;  22 342-346
  • 39 Heriot A, Tekkis P, Smith J, Bona R, Cohen R, Nicholls R. Management and outcome of pouch-vaginal fistulas following restorative proctocolectomy.  Dis Colon Rectum. 2005;  48 451-458
  • 40 Shah N, Remzi F, Massmann A, Baixauli J, Fazio V. Management and treatment outcome of pouch-vaginal fistulas following restorative proctocolectomy.  Dis Colon Rectum. 2003;  46 911-917
  • 41 Keighley M, Grobler S. Fistula complicating restorative proctocolectomy.  Br J Surg. 1993;  80 1065-1067
  • 42 Wexner S D, Rothenberger D A, Jensen L et al.. Ileal pouch vaginal fistulas: incidence, etiology, and management.  Dis Colon Rectum. 1989;  32 460-465
  • 43 Groom J S, Nicholls R J, Hawley P R, Phillips R K. Pouch-vaginal fistula.  Br J Surg. 1993;  80 936-940
  • 44 O'Kelly T J, Merrett M, Mortensen N J, Dehn T C, Kettlewell M. Pouch-vaginal fistulas after restorative proctocolectomy: aetiology and management.  Br J Surg. 1994;  81 1374-1375
  • 45 Burke D, VanLaarhoven C J, Herbst F, Nicholls R J. Transvaginal repair of pouch vaginal fistula.  Br J Surg. 2001;  88 241-245
  • 46 Zinicola R, Wilkinson K H, Nicholls R J. Ileal pouch-vaginal fistula treated by abdominoanal advancement of the ileal pouch.  Br J Surg. 2003;  90 1434-1435
  • 47 Thompson J S, Quigley E M. Anal sphincteroplasty for incontinence after ileal pouch-anal anastomosis. Report of two cases.  Dis Colon Rectum. 1995;  38 215-218
  • 48 Fonkalsrud E W, Bustorff-Silva J. Reconstruction for chronic dysfunction of ileoanal pouches.  Ann Surg. 1999;  229 197-204
  • 49 Nicholls R J, Gilbert J M. Surgical correction of the efferent ileal limb for disordered defaecation following restorative proctocolectomy with the S ileal reservoir.  Br J Surg. 1990;  77 152-154
  • 50 Liljeqvist L, Lindquist K. A reconstructive operation on malfunctioning S-shaped pelvic reservoirs.  Dis Colon Rectum. 1985;  28 506-511
  • 51 Fazio V W, Tjandra J J. Transanal mucosectomy. Ileal pouch advancement for anorectal dysplasia or inflammation after restorative proctocolectomy.  Dis Colon Rectum. 1994;  37 1008-1011
  • 52 Tulchinsky H, McCourtney J, Subba Rao K et al.. Salvage abdominal surgery in patients with a retained rectal stump after restorative proctocolectomy and stapled anastomosis.  Br J Surg. 2001;  88 1602-1606
  • 53 Sequens R. Cancer in the anal canal (transitional zone) after restorative proctocolectomy with stapled ileal pouch-anal anastomosis.  Int J Colorectal Dis. 1997;  12 254-255
  • 54 Oresland T, Fasth S, Nordgren S, Akervall S, Hulten L. Pouch size, the important functional determinant after restorative proctocolectomy.  Br J Surg. 1990;  77 265-269
  • 55 Klas J, Myers G A, Starling J R, Harms B A. Physiologic evaluation and surgical management of failed ileoanal pouch.  Dis Colon Rectum. 1998;  41 854-861
  • 56 Hulten L, Fasth S, Hallgren T, Oresland T. The failing pelvic conversion to continent ileostomy.  Int J Colorectal Dis. 1992;  7 119-121
  • 57 Ecker K W, Haberer M, Feifel G. Conversion of the failing ileoanal pouch to reservoir-ileostomy rather than to ileostomy alone.  Dis Colon Rectum. 1996;  39 977-980
  • 58 Karoui M, Cohen R, Nicholls J. Results of surgical removal of the pouch after failed restorative proctocolectomy.  Dis Colon Rectum. 2004;  47 869-875
  • 59 Ryan J A. Gracilis muscle flap for persistent perineal sinus of inflammatory bowel disease.  Am J Surg. 1984;  148 64-70
  • 60 Rius J, Nessim A, Nogueras J J, Wexner S D. Gracilis transposition in complicated perineal fistula and unhealed perineal wounds in Crohn's disease.  Eur J Surg. 2000;  166 218-222
  • 61 Bernell O, Lapidus A, Hellers G. Risk factors for surgery and recurrence in 907 patients with primary ileocecal Crohn's disease.  Br J Surg. 2000;  87 1697-1701
  • 62 Borley N R, Mortensen N J, Jewell D P. Preventing post-operative recurrence of Crohn's disease.  Br J Surg. 1997;  84 1493-1502
  • 63 Keh C, Shatari T, Yamamoto T, Menon A, Clark M A, Keighley M R. Jejunal Crohn's disease is associated with a higher postoperative recurrence rate than ileocaecal Crohn's disease.  Colorectal Dis. 2005;  7 366-368
  • 64 Heimann T M, Grenstein A J, Lewis B, Kaufman D, Heimann D M, Aufses Jr A H. Comparison of primary and reoperative surgery in patients with Crohn's disease.  Ann Surg. 1998;  227 492-495
  • 65 Polle S W, Slors J FM, Weverling G J, Gouma D J, Hommes D W. Recurrence after segmental resection for colonic Crohn's disease.  Br J Surg. 2005;  92 1143-1149
  • 66 Krupnick A S, Morris J B. The long-term results of resection and multiple resections in Crohn's disease.  Semin Gastrointest Dis. 2000;  11 41-51
  • 67 Steinhart H. Maintenance therapy in Crohn's disease.  Can J Gastroenterol. 2000;  14(Suppl C) 23C-28C
  • 68 Ellis L, Calhoun P, Kaiser D L. Post-operative recurrence in Crohn's disease. The effect of the initial length of bowel resection and operative procedure.  Ann Surg. 1984;  199 340-347
  • 69 Pennington L, Hamilton S R, Bayless T M, Cameron J L. Surgical management of Crohn's disease. Influence of disease at margin of resection.  Ann Surg. 1980;  192 311-318
  • 70 Fazio V W, Marchetti F, Church M et al.. Effect of resection margin on the recurrence of Crohn's disease in the small bowel. A randomized controlled trial.  Ann Surg. 1996;  224 563-573
  • 71 Tersigni R, Alessandroni L, Barreca M, Piovanello P, Prantera C. Does stapled functional end-to-end anastomosis affect recurrence of Crohn's disease after ileocolonic resection?.  Hepatogastroenterology. 2003;  50 1422-1425
  • 72 Hashemi M, Novell J R, Lewis A A. Side-to-side stapled anastomosis may delay recurrence in Crohn's disease.  Dis Colon Rectum. 1998;  41 1293-1296
  • 73 Munoz-Juarez M, Yamamoto T, Wolff B G, Keighley M R. Wide-lumen stapled anastomosis vs conventional end-to-end anastomosis in the treatment of Crohn's disease.  Dis Colon Rectum. 2001;  44 20-26
  • 74 Scarpa M, Angriman I, Barollo M et al.. Role of stapled and hand-sewn anastomosis in recurrence of Crohn's disease.  Hepatogastroenterology. 2004;  51 1053-1057
  • 75 Aeberhard P, Berchtold W, Riedtmann H J, Stadelmann G. Surgical recurrence of perforating and non-perforating Crohn's disease. A study of 101 surgically treated patients.  Dis Colon Rectum. 1996;  39 80-87
  • 76 Sachar D B, Subramani K, Mauer K et al.. Patterns of post-operative recurrence in fistulizing and stenotic Crohn's disease, a retrospective cohort of 71 patients.  J Clin Gastroenterol. 1996;  22 114-116
  • 77 Yamamoto T, Allan R N, Keighley M R. Perforating ileocecal Crohn's disease does not carry a high risk of recurrence but usually re-presents as perforating disease.  Dis Colon Rectum. 1999;  42 519-524
  • 78 McDonald P J, Fazio V W, Farmer R G et al.. Perforating and non-perforating Crohn's disease. An unpredictable guide to recurrence after surgery.  Dis Colon Rectum. 1989;  32 117-120
  • 79 Ryan W R, Yamamoto T, Keighley M R. Crohn's disease patients who quit smoking have a reduced risk of operation for recurrence.  Am J Surg. 2004;  187 219-225
  • 80 Bernell O, Lapidus A, Hellers G. Recurrence after colectomy in Crohn's colitis.  Dis Colon Rectum. 2001;  44 647-654
  • 81 Borley N R, Mortensen N J, Chaudry M A et al.. Recurrence after abdominal surgery for Crohn's disease: relationship to disease site and surgical procedure.  Dis Colon Rectum. 2002;  45 377-383
  • 82 Post S, Herfarth C, Bohm E et al.. The impact of disease pattern, surgical management, and individual surgeons on the risk for relaparotomy for recurrent Crohn's disease.  Ann Surg. 1996;  223 253-260
  • 83 Kumar D, Alexander-Williams J. Crohn's Disease and Ulcerative Colitis: Surgical Management. London; Springer-Verlag 1993: 89-101
  • 84 Tichansky D, Cagir B, Yoo E, Marcus S M, Fry R D. Stricturoplasty for Crohn's disease: meta-analysis.  Dis Colon Rectum. 2000;  43 911-919
  • 85 Ozuner G, Fazio V W, Lavery I C, Milsom J W, Strong S A. Reoperative rates for Crohn's disease following stricturoplasty. Long-term analysis.  Dis Colon Rectum. 1996;  39 1199-1203
  • 86 Hurst R D, Michelassi F. Stricturoplasty for Crohn's disease: techniques and long-term results.  World J Surg. 1998;  22 359-363
  • 87 Futami K, Arima S. Role of stricturoplasty in surgical treatment of Crohn's disease.  J Gastroenterol. 2005;  40(Suppl 16) 35-39
  • 88 Tonelli F, Ficari F. Stricturoplasty in Crohn's disease: surgical option.  Dis Colon Rectum. 2000;  43 920-926
  • 89 Dietz D W, Laureti S, Strong S A et al.. Safety and long-term efficacy of stricturoplasty in 314 patients with obstructing small bowel Crohn's disease.  J Am Coll Surg. 2001;  192 330-338
  • 90 Shatari T, Clark M A, Yamamoto T et al.. Long stricturoplasty is as safe and effective as short stricturoplasty in small-bowel Crohn's disease.  Colorectal Dis. 2004;  6 438-441
  • 91 Tonelli F, Fedi M, Paroli G M, Fazi M. Indications and results of side-to-side isoperistaltic stricturoplasty in Crohn's disease.  Dis Colon Rectum. 2004;  47 494-501
  • 92 Tjandra J J, Fazio V W. Stricturoplasty for ileocolic anastomotic strictures in Crohn's disease.  Dis Colon Rectum. 1993;  36 1099-1104
  • 93 Yamamoto T, Keighley M R. Long-term results of stricturoplasty for ileocolonic anastomotic recurrence in Crohn's disease.  J Gastrointest Surg. 1999;  3 555-560
  • 94 Andersson P, Olaison G, Hallbrook O, Sjodahl R. Segmental resection or subtotal colectomy in Crohn's colitis?.  Dis Colon Rectum. 2002;  45 47-53
  • 95 Cattan P, Bonhomme N, Panis Y et al.. Fate of the rectum in patients undergoing total colectomy for Crohn's disease.  Br J Surg. 2002;  89 454-459
  • 96 Brown C, MacLean A, Cohen Z, MacRae H, O'Connor B, McLeod R. Crohn's disease and indeterminate colitis and the ileal pouch-anal anastomosis: outcomes and patterns of failure.  Dis Colon Rectum. 2005;  48 1542-1549
  • 97 Regimbeau J M, Panis Y, Pocard M et al.. Long-term results of ileal pouch-anal anastomosis for colorectal Crohn's disease.  Dis Colon Rectum. 2001;  44 769-778
  • 98 Mylonakis E, Allan R N, Keighley M R. How does pouch construction for a final diagnosis of Crohn's disease compare with ileoproctostomy for established Crohn's proctocolitis?.  Dis Colon Rectum. 2001;  44 1137-1143
  • 99 Lowney J, Dietz D, Birnbaum E, Kodner I, Mutch M, Fleshmen J. Is there any difference in recurrence rates in laparoscopic ileocolic resection for Crohn's disease compared with conventional surgery? A long-term follow-up study.  Dis Colon Rectum. 2006;  49 58-63
  • 100 Bergamaschi R, Pessaux P, Arnaud J P. Comparison of conventional and laparoscopic ileocolic resection for Crohn's disease.  Dis Colon Rectum. 2003;  46 1129-1133
  • 101 Rosman A S, Melis M, Fichera A. Meta-analysis of trials comparing laparoscopic and open surgery for Crohn's disease.  Surg Endosc. 2005;  19 1549-1555
  • 102 Gutt C N, Onui T, Schemmer P, Mehrabi A, Buchler M W. Fewer adhesions induced by laparoscopic surgery?.  Surg Endosc. 2004;  18 898-906
  • 103 Hasegawa H, Watanabe M, Nishibori H, Okabayashi K, Hibi T, Kitajima M. Laparoscopic surgery for recurrent Crohn's disease.  Br J Surg. 2003;  90 970-973

Phillip FleshnerM.D. 

8737 Beverly Blvd., Ste. 101, Los Angeles, CA 90048

Email: pfleshner@aol.com

    >