The Thoracic and Cardiovascular Surgeon, Table of Contents Thorac Cardiovasc Surg 2007; 55(4): 239-244DOI: 10.1055/s-2006-955947 Original Cardiovascular © Georg Thieme Verlag KG Stuttgart · New YorkArtificial Chordae for Mitral Valve Repair: Mid-Term Clinical and Echocardiographic ResultsP. S. Risteski1 , T. Aybek1 , O. Dzemali1 , M. Doss1 , M. Scherer1 , S. Dogan1 , A. Moritz1 1Department of Thoracic and Cardiovascular Surgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany Recommend Article Abstract Buy Article(opens in new window) All articles of this category(opens in new window) Abstract Background: This paper reports on the mid-term clinical and echocardiographic results of mitral valve repair with chordal replacement. Methods: Sixty-nine patients (mean age 61 ± 14 years) underwent mitral valve repair with chordal replacement. The etiology was degenerative in 53 (77 %), rheumatic in 7 (10 %), ischemic in 6 (9 %) and infective in 3 (4 %). Mean ejection fraction was 58 ± 14. In 35 patients (51 %), a minimally invasive approach was used. Mean follow-up time was 45 ± 27 months. Results: Anterior leaflet chordae were replaced in 58 (84 %) patients. There were 3 operative deaths. Freedom from non-trivial recurrent mitral regurgitation (MR) was 81.3 ± 8.7 % at 97 months. Follow-up echocardiographic controls showed mild recurrent MR in 5 (8 %) patients and moderate in 2 (3.2 %). These two patients required reoperation due to mitral annulus redilation after suture annuloplasty. Competent neochordae were found at reoperation. Freedom from reoperation at 97 months was 96.6 ± 2.4 %. Four patients died during follow-up resulting in an actuarial survival of 87 ± 6.2 %. Conclusion: The replacement of chordae tendineae with ePTFE sutures during mitral valve repair has shown good mid-term results. The implantation of the neochordae can be also performed safely using minimally invasive procedures. Key words heart valve surgery - cardiovascular surgery - heart disease - mitral valve repair - chordae tendineae - expanded polytetrafluoroethylene Full Text References References 1 Braunberger E, Deloche A, Berrebi A. et al . Very long-term results (more than 20 years) of valve repair with Carpentier's techniques in nonrheumatic mitral valve insufficiency. Circul. 2001; 104 (Suppl 1) I8-I11 2 Cohn L, Couper G, Aranki S. et al . Long-term results of mitral valve reconstruction for regurgitation of the myxomatous mitral valve. J Thorac Cardiovasc Surg. 1994; 107 142-151 3 David T E. Replacement of chordae tendineae with expanded polytetrafluoroethylene. J Card Surg. 1989; 4 286-290 4 Salisbury P F, Cross C E, Reiben P A. Chorda tendinea tension. Am J Physiol. 1963; 205 385-392 5 Nigro J J, Schwartz D S, Bart R D. et al . Neochordal repair of the posterior mitral leaflet. J Thorac Cardiovasc Surg. 2004; 127 440-447 6 Zussa C, Poleser E, Rocco F, Valfre C. Artificial chordae in the treatment of anterior mitral leaflet pathology. Cardiovasc Surg. 1997; 5 125-128 7 Murakami T, Yagihara T, Yamamoto F, Uemura H, Yamashita K, Ishizaka T. Artificial chordae for mitral valve reconstruction in children. Ann Thorac Surg. 1998; 65 1377-1380 8 Casselman F P, Slycke S V, Wellens F. et al . Mitral valve surgery can now routinely be performed endoscopically. Circul. 2003; 108 (Suppl II) II48-II54 9 Smedira N G, Selman R, Cosgrove D M. et al . Repair of anterior leaflet prolapse: chordal transfer is superior to chordal shortening. J Thorac Cardiovasc Surg. 1996; 112 287-292 10 Phillips M R, Daly R C, Schaff H V. et al . Repair of anterior leaflet mitral valve prolapse: chordal replacement versus chordal shortening. Ann Thorac Surg. 2000; 69 25-29 11 David T E, Armstrong S, Sun Z. Replacement of chordae tendineae with Gore-Tex sutures: a ten-year experience. J Heart Valve Dis. 1996; 5 352-355 12 Henry W L, DeMaria A, Gramiak R. et al . Committee on nomenclature and standards in two-dimensional echocardiography. Circul. 1980; 62 212-225 13 Vetter H O, Burack J H, Factor S M. et al . Replacement of chordae tendineae of the mitral valve using the new expanded PTFE suture in sheep. Bodnar E, Yacoub M Biologic and Bioprosthetic Valves. New York; Yorke Medical Books 1986: 772-784 14 Revuelty J M, Garcia-Rinaldi R, Gaite L. et al . Generation of chordae tendineae with polytetrafluoroethylene stents: results of mitral valve chordal replacement in sheep. J Thorac Cardiovasc Surg. 1989; 97 98-103 15 Cochran R P, Kunzelman K S. Comparison of viscoelastic properties of suture versus porcine mitral valve chordae tendineae. J Card Surg. 1991; 6 508-513 16 Nistal F, Garzia-Martinez V, Arbe E. et al . In vivo experiment assessment of polytetrafluoroethylene trileaflet heart valve prosthesis. J Thoracic Cardiovasc Surg. 1990; 99 1074-1081 17 Kobayashi J, Sasako Y, Bando K, Minatoya K, Niwaya K, Kitamura S. Ten-year experience of chordal replacement with expanded polytetrafluoroethylene in mitral valve repair. Circul. 2000; 102 (Suppl III) III30-III34 18 Butany J, Collins M J, David T E. Ruptured synthetic expanded polytetrafluoroethylene chordae tendineae. Cardiovasc Pathol. 2004; 13 182-184 19 Zussa C. Different applications of ePTFE valve chordae: surgical technique. J Heart Valve Dis. 1996; 5 356-361 20 Grossi E A, Galloway A C, LaPietra A. et al . Minimally invasive mitral valve surgery: a 6-year experience with 714 patients. Ann Thorac Surg. 2002; 74 660-664 MD Petar S. Risteski Department of Thoracic and Cardiovascular SurgeryJohann Wolfgang Goethe University Theodor-Stern-Kai 7 60590 Frankfurt am Main Germany Phone: + 49 69 63 01 61 41 Fax: + 49 69 63 01 58 49 Email: docpsr@yahoo.com