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Synfacts 2007(2): 0126-0126  
DOI: 10.1055/s-2006-955768
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Taiwaniaquinoids

Contributor(s): Philip Kocienski, Fiona Black
G. Liang, Y. Xu, I. B. Seiple, D. Trauner*
University of California, Berkeley, USA
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Publication History

Publication Date:
23 January 2007 (online)

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Significance

A convergent approach to the taiwaniaquinoid family of tricyclic diterpenoids is reported. Aryl vinyl ketone A is employed in an aromatic Nazarov cyclization to generate enol triflate C, which provides a handle for structural diversification.