Mit Primärprävention bereits im Kindesalter beginnen - Risikofaktoren für eine Atherosklerose beim jungen Menschen

Atherosklerotische Veränderungen in der Aorta und den Koronararterien finden sich bereits im Kindes- und Jugendalter. Zahlreichen Autopsiestudien sowie nichtinvasiven Untersuchungen zufolge sind die bekannten kardiovaskulären Risikofaktoren bereits in jungen Jahren Ursache für die Entstehung früher atherosklerotischer Plaques und führen, vor allem bei Persistenz der Risikofaktoren, zur klinischen Manifestation von kardiovaskulären Erkrankungen im Erwachsenenalter. Eine Primärprävention oder Intervention bei Vorhandensein von Risikofaktoren ist daher essenziell und sollte bereits frühzeitig einsetzen.

Atherosclerotic changes in the aorta and coronary arteries can be found already early in childhood and adolescence. Numerous autopsy and non invasive studies clearly demonstrate, that the known cardiovascular risk factors play a causative role for the initiation of early atherosclerotic lesions. In case of persistence of risk factors, atherosclerosis often progresses and results in clinical manifestation of cardiovascular diseases in adulthood. Therefore, primary prevention or intervention in case of presence of cardiovascular risk factors is important and should be initiated early in life.

Key Words

atherosclerosis - early manifestation - risk factors - prevention

Literatur

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1 Pathobiological Determinants of Atherosclerosis in Youth

2 Atherosclerosis Risk in Communities

3 Coronary Artery Risk Development in Young Adults

Anschrift für die Verfasser