Abstract
Giant cell myocarditis (GCM) is a rare and frequently fatal disorder. Patients suffer
of ventricular arrhythmias or congestive heart failure. Here we describe a patient
with cardiogenic shock and histological verified GCM. The patient was saved by implantation
of extracorporeal membrane oxygeneation (ECMO) device and concomitant application
of Rabbit antithymocyte globuline (rATG, Thymoglobulin, Sangstat), cyclosporine, and
steroids in the acute event. 12 months after the crisis the patient evidences NYHA
class I heart function and only a moderate impairment of heart function (EF 55 %).
The novel utilisation of ECMO in GCM related cardiogenic shock and application of
rATG have prooven life-saving in this patient. Studies utilizing rATG in the treatment
of GCM are warrented.
Key words
Giant cell myocarditis - autoimmunity - rATG - ECMO - myocarditis - VAD - surgery
References
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