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Synthesis 2005(17): 2833-2834  
DOI: 10.1055/s-2005-872179
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York

Improved Method for the Synthesis of 1,2,4-Triazolo[4,5-a]pyrimidin-5-ones

George Bratulescu*
University of Craiova, Faculty of Chemistry, 13 A.I. Cuza, 1100 Craiova, Romania
e-Mail: gbratulescu@operamail.com;
Further Information

Publication History

Received 6 April 2005
Publication Date:
23 August 2005 (online)

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Abstract

Five new 1,2,4-triazolo[4,5-a]pyrimidin-5-ones were synthesised in good yield in a paste-like medium using microwave irradiation.

Keywords

microwave - paste-like medium - condensation - alcohol

    References

  • 1 Rahmani A. Romero MA. Salas JM. Quiros M. Cienfuegos GA. Inorg. Chim. Acta  1996,  247:  51 
    CrossrefGoogle Scholar
  • 2 Lee SJ, Macina OT, Yu DT, Frierson MR, Konishi Y, Kondo K, and Sugitani M. inventors; Eur. Pat. Appl. EP  728759.  ; Chem. Abstr. 1996, 125, 221861
  • 3 Jaehne G, Helsberg M, Winkler I, Gross G, and Scholl T. inventors; Eur. Pat. Appl. EP  589335.  ; Chem. Abstr. 1994, 121, 134145
  • 4 Romero MA. Salas JM. Quiros M. Williams DJ. Molina J. Transition Met. Chem.  1993,  18:  595 
    Google Scholar
  • 5 Pees KJ. inventors; Eur. Pat. Appl. EP  613900.  ; Chem. Abstr. 1994, 121: 280667
  • 6 Pees KJ, Klaus J, and Albert G. inventors; Eur. Pat. Appl. EP  550113.  ; Chem. Abstr. 1993, 119, 271190
  • 7 Mourad G. King J. Planta  1992,  188:  491 
    Google Scholar
  • 8 Kleschick WA. In Chemistry of Plant Protection, Vol. 10   Stetter J. Springer; Berlin Heidelberg: 1994.  p.119 
    Google Scholar
  • 9 Walsh GM. Suleymanov OD. Cardiovasc. Drug Rev.  1991,  9:  237 
    CrossrefGoogle Scholar
  • 10 Urleb U. Stanovnik B. Stibilj V. Tisler M. Heterocycles  1986,  24:  1899 
    CrossrefGoogle Scholar
  • 11 Fischer G. Adv. Heterocycl. Chem.  1993,  57:  81 
    Google Scholar
  • 12 Cocco MT. Congiu C. Maccioni A. Onnis V. J. Heterocycl. Chem.  1992,  29:  1341 
    CrossrefGoogle Scholar
  • 13 Kelley JL. Davis RG. McLean EW. Glen RC. Soroko FE. Cooper BR. J. Med. Chem.  1995,  38:  3884 
    CrossrefGoogle Scholar
  • 14 Badawey E.-SAM. J. Heterocycl. Chem.  1996,  33:  229 
    CrossrefGoogle Scholar
  • 15 Bratulescu G. Le Bigot Y. Delmas M. Synth. Commun.  2000,  30:  171 
    CrossrefGoogle Scholar
  • 16 Bratulescu G. Le Bigot Y. Delmas M. Rev. Chim. (Bucharest)  2000,  5:  354 
    Google Scholar
  • 17 Bratulescu G. Le Bigot Y. Delmas M. Synth. Commun.  1997,  27:  1037 
    CrossrefGoogle Scholar