Chemical Composition and Anti-Inflammatory Activity of the Volatile Fractions from the Bark of Eight Mexican Bursera Species

Abstract

The volatile fractions from the bark of eight species of Mexican Bursera were obtained using steam distillation and were subjected to tandem GC-MS analysis for identification of the main constituents. The most abundant components of steam volatiles were monoterpenoids from which α-terpineol, terpinen-4-ol, α-thujene, linalool and limonene were most frequently isolated. A series of sesquiterpenes and long-chain hydrocarbons were isolated and identified from the barks of some of the studied species. Some volatiles were assayed for anti-inflammatory activity using the TPA-induced ear edema bioassay in mice. The volatile fraction from Bursera lancifolia was about half as active as indomethacin.

Key words

Bursera - volatiles - GC-MS - monoterpenes - sesquiterpenes - hydrocarbons - anti-inflammatory activity

References

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