Planta Med 2005; 71(9): 847-851
DOI: 10.1055/s-2005-871226
Original Paper
Natural Product Chemistry
© Georg Thieme Verlag KG Stuttgart · New York

Four New Benzofurans from Seeds of Styrax perkinsiae

Qi-Lin Li1 , Bo-Gang Li1 , Hua-Yi Qi1 , Xiao-Ping Gao2 , Guo-Lin Zhang1
  • 1Chengdu Institute of Biology, the Chinese Academy of Sciences, Chengdu, P. R. China
  • 2Pharmaceutical Institute of Di-Ao Pharmaceutical Group, Chengdu, P. R. China
Further Information

Publication History

Received: December 13, 2004

Accepted: February 25, 2005

Publication Date:
29 July 2005 (online)

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Abstract

Four new benzofurans trans-5-(3-hydroxypropyl)-7-methoxy-2-[2,3-dihydro-3-hydroxymethyl-7-methoxy-2-(3-methoxy-4-hydroxyphenyl)-benzofuran-5-yl]benzofuran (1), (E)-5-(2-formylvinyl)-7-methoxy-2-(3,4-methylenedioxyphenyl)benzofuran (2), 5-(3-butanoyloxypropyl)-7-methoxy-2-(3,4-methylenedioxyphenyl)benzofuran (3), and 5-(3-hydroxypropyl)-7-hydroxy-2-(3,4-methylenedioxyphenyl) benzofuran (4) were isolated from the seeds of Styrax perkinsiae, together with egonol (5), demethoxyegonol (6), egonol acetate (7), demethoxyegonol acetate (8), egonol glucoside (9), egonol gentiobioside (10), egonol gentiotrioside (11), β-sitosterol (12), and β-daucosterol (13). Their structures were established by spectroscopic and chemical methods. Compounds 1 and 4 exhibited cytotoxic activity in vitro using two breast cancer cell lines MCF-7 and MDA-MB-231.

References

Prof. Dr. Guolin Zhang

Chengdu Institute of Biology

The Chinese Academy of Sciences

P. O. Box 416

Chengdu 610041

People’s Republic of China

Phone: +86-28-8522-5401

Fax: +86-28-8522-5401

Email: Zhanggl@cib.ac.cn