ABSTRACT
Type 1 collagen loss in the dermis is one of the primary causes of wrinkles seen in
aged skin. Dermal fillers using type 1 collagen derived from bioengineered skin are
now being used to treat facial wrinkles. These fillers, known by the trade names of
CosmoDerm and CosmoPlast, can be used alone or in combination with hyaluronic acid
fillers. The benefit of collagen-based dermal fillers is decreased downtime, decreased
bruising, decreased pain on injection, and the ability to return lost structural components
to aged skin. Many aesthetic physicians are beginning to use collagen- and hyaluronic-containing
fillers in combination to replace both of these natural components of the skin that
are lost during the aging process.
KEYWORDS
Collagen - elastin - hyaluronic acid - dermal filler - CosmoPlast - CosmoDerm - Hylaform
- Restylane - Captique - Juvederm - photoaging - wrinkles - bioengineered
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Leslie BaumannM.D.
1295 NW 14th Street St K, Miami FL 33125