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Semin intervent Radiol 2003; 20(4): 253-268
DOI: 10.1055/s-2004-828936
DOI: 10.1055/s-2004-828936
History, Principles, and Techniques of Radiofrequency Ablation
Further Information
Publication History
Publication Date:
20 July 2004 (online)
ABSTRACT
Radiofrequency (RF) tumor ablation has been shown to be a useful method for creating thermally induced coagulation necrosis, using either a percutaneous approach with image-guidance, laparoscopic guidance, or direct surgical placement of thin electrodes into tissues to be treated. RF has gained widespread clinical use for the treatment of hepatic, renal, and bony malignancies. This article discusses the principles and technical considerations of RF ablation, with the goal of defining optimal parameters for the therapy of focal tumors. These parameters include innovations that permit large volume tumor ablation (i.e., multitined and internally cooled electrodes), as well as adjuvant therapies that can modulate tumor physiology to allow improved tumor destruction (i.e., altered tissue conductivity and blood flow). Recent adjuvant chemotherapy also will be reviewed. Finally, the principles governing the safe use of the system, including proper grounding pad placement, will be addressed.
KEYWORDS
Radiofrequency (RF) ablation - tumor therapy - electrode
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