Zusammenfassung
Für die Behandlung von Lebermetastasen bietet die interventionelle Radiologie sowohl
lokale wie lokoregionäre Therapiekonzepte an. Während lokale Konzepte als bildgeführte
interstitielle Techniken eingesetzt werden, ist für die lokoregionäre Verteilung von
antitumorösen Wirkstoffen der vaskuläre Zugang ideal. In diesem Artikel werden von
den derzeit interstitiell eingesetzten Ablationsmethoden die Radiofrequenz, die laserinduzierte
Thermotherapie und die CT-gesteuerte Brachytherapie anhand der verfügbaren Literatur
bewertet. Aus dem Bereich der lokoregionär vaskulären Techniken finden sich Analysen
der intraarteriellen Chemotherapie über minimalinvasiv implantierte Portsysteme sowie
die transarterielle Chemoembolisation.
Abstract
Interventional radiology offers not only local but also loco-regional therapeutic
concepts for the treatment of liver metastases. While the local concepts are employed
as image-guided, interstitial techniques, a vascular access is ideal for the loco-regional
distribution of anti-tumour drugs. In the present article interstitial employed ablation
methods such as radiofrequency ablation, laser-induced thermotherapy and CT-guided
brachytherapy are evaluated on the basis of the available literature. The field of
loco-regional vascular techniques contributes analyses of intra-arterial chemotherapy
via minimally invasively implanted port systems as well as transarterial chemoembolisation.
Schlüsselwörter
Tumorablation - Lebermetastasen - Chemotherapie - Intervention
Key words
Tumour ablation - liver metastases - chemotherapy - interventions
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Prof. Dr. J. Ricke
Klinik für Strahlenheilkunde, Charité Virchow-Klinikum
Augustenburger Platz 1
13353 Berlin
Phone: ++ 49/30/4 50 55 70 01
Fax: ++ 49/30/4 50 55 79 01
Email: jens.ricke@charite.de
