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DOI: 10.1055/s-2004-813122
© Georg Thieme Verlag KG Stuttgart · New York
Juvenile Papillomatosis (JP) of the Female Breast (Swiss Cheese Disease) - Role of Breast Ultrasonography
Juvenile Papillomatose (JP) der weiblichen Brust (Swiss Cheese disease) - Bedeutung der SonographiePublication History
received: 12.8.2003
accepted: 5.3.2004
Publication Date:
07 February 2005 (online)
Zusammenfassung
Die juvenile Papillomatose ist eine sehr seltene benigne Brustdrüsenerkrankung. Beschrieben wird ein Fall einer 16-jährigen Patientin. Palpatorisch fand sich ein ca. 8 cm großer verschiebbarer Knoten. Sonographisch zeigte sich eine ovale, gut abgrenzbare, echoarme heterogene Läsion mit multiplen zystischen Foci. Klinisch und mammographisch ist die Vorhersage einer JP nicht möglich. Die Sonographie hingegen ist hilfreich und ermöglicht eine relativ gute Abgrenzung gegenüber einer einfachen Zyste, einem Fibroadenom, einem phylloiden Tumor oder einem intrazystischen Papillom und Karzinom. Die Diagnosesicherung sollte präoperativ über eine Stanzbiopsie erfolgen. Eine offene Biopsie mit Exzision im Gesunden wird aufgrund einer möglichen späteren Karzinomentstehung angeraten.
Abstract
This report summarises the imaging findings of juvenile papillomatosis (JP) in a 16-year-old woman. Sonographically, the lesion was oval, well defined, heterogeneous with multiple small, cystic spaces. Ultrasonography can be helpful in differentiating between JP and similar cystic lesions, fibroadenomas, phyllodes tumours, intracystic papillomas and carcinomas. A core needle biopsy is still needed to confirm the diagnosis. An open biopsy with excision of the lesion is mandatory, mere observation is inadequate because of insufficient knowledge about the direct relationship between JP and subsequent cancer.
Schlüsselwörter
Brust - Juvenile Papillomatose - Mammasonographie - Mammographie - MRT - Pathologie
Key words
Breast - juvenile papillomatosis - ultrasonography - mammography - magnetic resonance imaging - pathology
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OA Dr. med. R. Ohlinger
Lt. Funktionsbereich Senologie/Brustzentrum, Ernst Moritz Arndt University of Greifswald,
Department of Gynecology and Obstetrics
Wollweberstraße 1 - 3
17489 Greifswald
Germany
Phone: +49/38 34/86 65 10
Fax: +49/38 34/86 65 41
Email: ralf.ohlinger@uni-greifswald.de