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Am J Perinatol 2003; 20(5): 233-238
DOI: 10.1055/s-2003-42343
Copyright © 2003 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Severe Anemia in a 25-Day-Old Infant Due to Gastric Teratoma with Focal Neuroblastoma

Samantha Hook1 , Richard  Spicer1 , Jonathan  Williams4 , David Grier2 , Steve Lowis3 , Annabel Foot3 , Consolato Sergi5
  • 1Department of Paediatric Surgery, Children's Hospital, Bristol, United Kingdom
  • 2Department of Paediatric Radiology, Children's Hospital, Bristol, United Kingdom
  • 3Department of Paediatric Oncology, Children's Hospital, Bristol, United Kingdom
  • 4Directorate of Laboratory Medicine, Bristol Royal Infirmary, Bristol, United Kingdom
  • 5Department of Paediatric Pathology, St. Michael's Hospital, Bristol, United Kingdom
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Publication History

Publication Date:
18 September 2003 (online)

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ABSTRACT

Gastric teratoma is an extremely rare embryonic neoplasm containing tissue from all three germ layers (ectoderm, endoderm, and mesoderm). A 25-day-old infant presented with anemia and a palpable abdominal mass. Computed tomography (CT) scanning showed a solid and cystic multiloculated tumor of mixed echogenicity and calcifications. An encapsulated bleeding tumor localized to the posterior wall of the stomach with extension to a bowel segment was promptly excised. Histology revealed a grade III immature teratoma with small foci of neuroblastoma. To the best of our knowledge, this is the first infant with gastric teratoma containing foci of neuroblastoma causing bleeding and anemia as presentation symptoms at neonatal age.

KEYWORDS

Germ cell tumor - neuroblastoma - anemia

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