Sleep Breath 2002; 06(4): 181-188
DOI: 10.1055/s-2002-36529
COMMENTARY

Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Pulmonary Hypertension, Sleep-Disordered Breathing, and Beta Blockers in Heart Failure Patients

Robert P. Blankfield1,2
  • 1Department of Family Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio
  • 2University Hospitals Primary Care Physician Practice, Berea, Ohio
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Publication History

Publication Date:
13 January 2003 (online)

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ABSTRACT

Heart failure patients with pulmonary hypertension have a worse prognosis than heart failure patients with normal pulmonary artery pressures. Heart failure is usually considered the cause of the pulmonary hypertension when the two conditions coincide. However, there is evidence that sleep-disordered breathing may be responsible for the pulmonary hypertension in these patients, and the worsened outcomes in heart failure patients with pulmonary hypertension may be due to sleep-disordered breathing. In addition, sleep-disordered breathing may provide an explanation for the beneficial effect of beta-adrenergic antagonists in heart failure patients.

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