Semin Neurol 2000; 20(4): 439-446
DOI: 10.1055/s-2000-13176
Copyright © 2000 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Non-Alzheimer Dementias

Peter Nestor1 , John Hodges1,2
  • 1University Department of Neurology, Addenbrooke's Hospital, Cambridge, England
  • 2MRC Cognition and Brain Sciences Unit, Cambridge, England
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Publication History

Publication Date:
03 March 2004 (online)

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ABSTRACT

The past decade has seen a considerable resurgence of interest in non-Alzheimer forms of neurodegenerative dementia. Advances in our understanding and classification of these conditions have taken place over a diverse range of disciplines: from genetics and immunohistochemistry to neuropsychology and psychiatry. The aim of this article is to review, from a clinician's perspective, our current understanding of the major degenerative dementias that fall into the differential diagnosis of Alzheimer's disease. The clinical variants of frontotemporal dementia (semantic dementia, progressive nonfluent aphasia, and dementia of a frontal type), amyotrophic lateral sclerosis associated dementia, corticobasal degeneration, and dementia with Lewy bodies are considered.

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