physioscience 2025; 21(S 01): S4
DOI: 10.1055/s-0045-1808114
Abstracts
Vorträge

Comparison of changes in physical activity between participants of the supervised Patient Education and Exercise Therapy Program GLA:D®​ and participants of the Osteoarthritis Initiative

M Rafiei
1   Institute for Computational Systems Biology, University of Hamburg, Hamburg, Germany
2   Department of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Germany
,
S Das
1   Institute for Computational Systems Biology, University of Hamburg, Hamburg, Germany
2   Department of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Germany
,
E M Roos
3   Center for Muscle and Joint Health, Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
,
S T Skou
3   Center for Muscle and Joint Health, Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
4   The Research and Implementation Unit PROgrez, Department of Physiotherapy and Occupational Therapy, Næstved-Slagelse-Ringsted Hospitals, Slagelse, Denmark
,
J Baumbach
1   Institute for Computational Systems Biology, University of Hamburg, Hamburg, Germany
5   Computational Biomedicine Lab, Department of Mathematics and Computer Science, University of Southern Denmark, Odense, Denmark
,
L Baumbach
2   Department of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Germany
› Author Affiliations
› Further Information
Also available atergoLinkphysioLink
 
 

    Objective GLA:D®​ (Good Life with osteoArthritis in Denmark) is an evidence-based program to treat patients with knee and hip osteoarthritis (OA). A recent study showed that not only was pain reduced and quality of life improved, but several participants also increased their physical activity levels after the program. Yet, it is unclear whether these changes result from the program or natural fluctuations. We aim to assess the impact of GLA:D®​ on changes in physical activity (PA) after one year. Additionally, we will evaluate changes in pain levels and quality of life (QOL). We compare these outcomes between GLA:D®​ participants and patients from the Osteoarthritis Initiative (OAI), who did not receive any specific treatment.

    Method We used patient-data from the GLA:D®​ registry (n=22,063) and the OAI (n=4,210). Our primary outcome of interest PA, was measured with the UCLA PA scale (1 low to 10 high) and the Physical Activity Scale for the Elderly (PASE) (0 low to 531 high), respectively. Pain intensity was measured on a Visual Analog Scale (VAS) in GLA:D®​ and in OAI (0 low to 100 high, and 0 low to 10 high, respectively). QOL was measured with the KOOS QOL scale (0 low – 100 high) in both datasets. We mapped the PASE scores to the UCLA scale and the pain intensity scores from the OAI to the GLA:D®​ scores. Afterward, we calculated the number of individuals who experienced an increase, maintenance or decrease in the outcome after one year. For PA, maintenance was defined as reporting the same UCLA PA level, maintenance of pain intensity was defined as less than 20 points deviation from the baseline value, and QOL maintenance was defined as reporting the same level+/- 10 points.

    Result One year after the GLA:D®​ program, 36.65% of participants had increased their PA, 32.98% remained unchanged, and 28.37% had decreased their PA. Within the OAI, 33.87%, 31.88%, and 34.25% increased, maintained, and decreased their PA levels, respectively.

    Regarding pain intensity, 9.18% of the GLA:D®​ participants reported increased pain levels by at least 20 points, 52.12% reported no change, and 38.70% reported a decrease in pain of at least 20 points. Meanwhile, in the OAI, 27.26%, 36.32%, and 36.42% reported an increase, maintenance, and decrease, respectively.

    In QOL, an increase of at least 10 points was observed in 55.10% of GLA:D®​ participants, 30.26% remained unchanged, and 14.65% reported a decrease of at least 10 points. In the OAI cohort, 31.81%, 50.29%, and 17.91% reported an increase, unchanged, and a decrease, respectively.

    Conclusion GLA:D®​ participants reported more often increased PA, QOL, and reduced pain than OAI partients who did not participate in the program. However, a limitation remains due to demographic differences between the GLA:D®​ and OAI participants, which might influence our findings. We plan to balance the data in the next step to reduce this potential influence before comparing changes between the datasets.


     

    Conflict of Interest

    Es besteht kein Interessenkonflikt

    Publication History

    Article published online:
    21 May 2025

    © 2025. Thieme. All rights reserved.

    Georg Thieme Verlag KG
    Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany