Updates in Management of Large Hemispheric Infarct

Charlene J. Ong; Stefanos Chatzidakis; Jimmy J. Ong; Steven Feske

doi:10.1055/s-0044-1787046

Seminars in Neurology, Inhaltsverzeichnis

Semin Neurol 2024; 44(03): 281-297
DOI: 10.1055/s-0044-1787046

Review Article

Updates in Management of Large Hemispheric Infarct

Charlene J. Ong

¹Department of Neurology, Chobanian and Avedisian School of Medicine, Boston University School of Medicine, Boston, Massachusetts

²Department of Neurology, Boston Medical Center, 1 Boston Medical Center PI, Boston, Massachusetts

,

Stefanos Chatzidakis

³Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts

,

Jimmy J. Ong

⁴Department of Neurology, Sidney Kimmel Medical College, Philadelphia, Pennsylvania

⁵Department of Neurology, Jefferson Einstein Hospital, Philadelphia, Pennsylvania

,

Steven Feske

¹Department of Neurology, Chobanian and Avedisian School of Medicine, Boston University School of Medicine, Boston, Massachusetts

²Department of Neurology, Boston Medical Center, 1 Boston Medical Center PI, Boston, Massachusetts

› Institutsangaben

Abstract

This review delves into updates in management of large hemispheric infarction (LHI), a condition affecting up to 10% of patients with supratentorial strokes. While traditional management paradigms have endured, recent strides in research have revolutionized the approach to acute therapies, monitoring, and treatment. Notably, advancements in triage methodologies and the application of both pharmacological and mechanical abortive procedures have reshaped the acute care trajectory for patients with LHI. Moreover, ongoing endeavors have sought to refine strategies for the optimal surveillance and mitigation of complications, notably space-occupying mass effect, which can ensue in the aftermath of LHI. By amalgamating contemporary guidelines with cutting-edge clinical trial findings, this review offers a comprehensive exploration of the current landscape of acute and ongoing patient care for LHI, illuminating the evolving strategies that underpin effective management in this critical clinical domain.

Keywords

cerebral edema - ischemic stroke - space-occupying mass effect - thrombectomy

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Referenzen

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