Thorac Cardiovasc Surg 2024; 72(S 01): S1-S68
DOI: 10.1055/s-0044-1780686
Monday, 19 February
Kurz- und Langzeitergebnisse Nach Chirurgischer Therapie der Typ A Dissektion

Concomitant Coronary Artery Bypass Grafting in Acute Type A Aortic Dissection Complicated by Coronary Malperfusion—Experience and Decision Making

Authors

  • L. Pitts

    1   German Heart Institute Berlin, Berlin, Deutschland
  • M. Kofler

    1   German Heart Institute Berlin, Berlin, Deutschland
  • M. Montagner

    1   German Heart Institute Berlin, Berlin, Deutschland
  • R. Heck

    1   German Heart Institute Berlin, Berlin, Deutschland
  • S. Kurz

    1   German Heart Institute Berlin, Berlin, Deutschland
  • S. Buz

    1   German Heart Institute Berlin, Berlin, Deutschland
  • V. Falk

    1   German Heart Institute Berlin, Berlin, Deutschland
  • J. Kempfert

    1   German Heart Institute Berlin, Berlin, Deutschland
 

    Background: The management of acute type A aortic dissection (ATAAD) complicated by coronary malperfusion can be challenging. In this study, we report a single center experience and revascularization strategy for patients with ATAAD and coronary malperfusion.

    Methods: From 01/2000 to 12/2021, 195 patients with preoperative coronary malperfusion and involvement of the aortic root underwent surgery for ATAAD. Coronary malperfusion included presence of elevated cardiac enzymes, electrocardiographic signs of ischemia and/or new wall motion abnormalities in ultrasound. Patients were divided into four subgroups according to their pattern of coronary dissection (Neri A = ostial involvement by the dissection, Neri B = dissection extending into the coronary artery, Neri C = circumferential detachment or complete avulsion of the coronary artery). A novel subclass called “Neri negative” defined by aortic root dissection without coronary dissection was added. Additional subgroup analysis was performed involving patients receiving concomitant CABG either as part of a planned strategy or unplanned as a bailout strategy in case of persisting low cardiac output.

    Results:

    Perioperative variables, n (%)

    Total (n = 195)

    Neri negative (n = 43)

    Neri A (n = 43)

    Neri B (n = 74)

    Neri C (n = 35)

    p-Value

    Aortic root replacement

    79 (41)

    13 (30)

    16 (37)

    25 (34)

    25 (71)

    < 0.001

    LCA dissection

    53 (27)

    0 (0)

    20 (47)

    29 (39)

    4 (11)

    < 0.001

    RCA dissection

    131 (67)

    0 (0)

    33 (77)

    63 (85)

    35 (100)

    < 0.001

    Concomitant CABG

    62 (32)

    4 (9)

    5 (12)

    21 (28)

    32 (91)

    < 0.001

    30 day mortality

    82 (42)

    21 (49)

    12 (28)

    30 (41)

    19 (54)

    0.087

    Planned CABG (n = 46)

    Bailout CABG (n = 16)

    Neri B

    10 (22)

    11 (69)

    0.001

    Neri C

    29 (63)

    3 (19)

    0.005

    30 day mortality

    22 (48)

    13 (81)

    0.042

    Conclusion: In case of Neri negative and Neri A patients, concomitant CABG may be restricted to isolated cases and may therefore not be necessary in general. Neri C patients should undergo concomitant CABG as well as liberal decision for aortic root replacement. Planned CABG in Neri B patients may be advisable as bailout CABG in this group is associated with poor outcome.


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    Publikationsverlauf

    Artikel online veröffentlicht:
    13. Februar 2024

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