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Synfacts 2024; 20(09): 0988
DOI: 10.1055/s-0043-1773367
Innovative Drug Discovery and Development

HRO761: a First-in-Class Non-Covalent WRN Inhibitor with Synthetic Lethality in MSI Cancers

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    Contributor(s):

  • Antonia F. Stepan (Roche)

  • Seong Heon Kim (Hyundai Pharm)

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Key words

WRN - synthetic lethality - MSI cancers - non-covalent WRN inhibitor - first-in-class inhibitor - HRO761 - clinical candidates


Publication History

Article published online:
16 August 2024

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