Portal Hypertensive Gastropathy Prevalence And Grading According To Liver Diseases Severity

Aims The goal of this research is to evaluate the prevalence of PHG and assess its relation to esophageal varices (EV) grading and chronic liver diseases (CLD) stage.

Methods This analytical, descriptive, cross-sectional study was conducted at one center at one year, 1440 patients were liver cirrhosiss (CLD screening for varices, upper GIT bleeding, and/or anaemia), demographic parameters, essential laboratory investigation, radiological assesement by ultrasound (US) and detailed endoscopic finding (EV grading, PHG grading according to McCormack classification, Fundal varcies, others upper GI ectopic varcies) and CLD severity assessed (Child-peugh stage) were recorded and analysed ([Table 1]).

Table 1

Results The prevalence of PHG was1128 (78 %) of the cirrhosis patients, 33.8%- 43.2% were mild to moderate PHG, only 1.4% of patients diagnosed by severe PHG, male/female showed significant difference between PHG and non PHG (p< 0.001). bilirubin and albumin value showed significant difference p value 0.02, 0.04 between nonPGH (mean/SD2.2±0.8, 3.3±0.4) and PHG (2.3±1.7, 3.04±0.4). 41.1% of the patients were PHG associated no EV, 37.3% were both PHG concomitant EV, 20.8% were EV associated nonPHG while 0.8% of cirrhosis patients were not EV related to PHG. There were a significant association between EV and PHG with 23.7% diagnosed mild PHG associated with EV grade 1 and 26.2% were mild PHG associated with Child. P (C), while 0.07% of patients were severe PHG associated with EV grade 3-4 and 0.7% were severe PHG in child. p (C) patients [1] [2].

Conclusions Portal hypertensive gastropathy is high prevalent in liver cirrhosis patient. Mild to moderate grades associated with no to low grade varies in advanced liver decompensation.

 

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Conflicts of interest

Authors do not have any conflict of interest to disclose.

• 1 Tiwari PS, Kc S, Sharma D. et al. (August 21, 2019) Prevalence of Portal Hypertensive Gastropathy in Chronic Liver Disease and Correlation with the Severity of Liver disease. Cureus 11 (08) e5454
• 2 Wu R, Liu K, Shi C, Tian H, Wang N.. Risk factors for portal hypertensive gastropathy. BMC Gastroenterol 2022; 22 (01) 436 PMID: 36241992; PMCID: PMC9563123

Publikationsverlauf

Artikel online veröffentlicht:
14. April 2023