J Pediatr Intensive Care
DOI: 10.1055/s-0043-1762909
Review Article

Procedural Sedation in Congenital Heart Disease

Saadeh Al-Jureidini
1   Division of Cardiology, Department of Pediatrics, SSM Health Cardinal Glennon Children's Hospital, Saint Louis University School of Medicine, St. Louis, Missouri, United States
,
2   Department of Pharmacy, SSM Health Cardinal Glennon Children's Hospital, St. Louis, Missouri, United States
,
Reema Patel
3   American Board of Pediatrics and Subboard of Pediatric Cardiology, John Hopkins All Children's Hospital, St. Petersburg, Florida, United States
,
Renuka Peterson
1   Division of Cardiology, Department of Pediatrics, SSM Health Cardinal Glennon Children's Hospital, Saint Louis University School of Medicine, St. Louis, Missouri, United States
,
Michael Czajka
4   Division of Cardiology, Department of Pediatrics, SSM Health Cardinal Glennon Children's Hospital, St. Louis, Missouri, United States
,
Andrew Fiore
5   Division of Cardiothoracic Surgery, Department of Surgery, SSM Health Cardinal Glennon Children's Hospital, Saint Louis University School of Medicine, St. Louis, Missouri, United States
› Institutsangaben

Abstract

Procedural sedation in patients with congenital heart disease (CHD) is associated with significant morbidity and mortality. It is vital for the practitioner to fully understand the complexity of lesions, their hemodynamics, and the impact of medications commonly used for procedural sedation on the stability of systemic vascular resistance and pulmonary flow. According to the literature, we explain the interaction of the systemic vascular resistance and pulmonary flow in such lesions and divide them into five categories outlined in this article: (1) CHDs with left-to-right shunt with normal pulmonary arterial pressure and resistance, (2) CHD with left-to-right shunt and moderate to severe elevation of pulmonary arterial pressure with near-normal pulmonary vascular resistance, (3) CHD with pulmonary flow dependent on systemic vascular resistance, (4) patients with congenital coronary stenosis and coronary anomalies, and 5) aortic obstructive lesions.



Publikationsverlauf

Eingereicht: 02. November 2022

Angenommen: 09. Januar 2023

Artikel online veröffentlicht:
24. Februar 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
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