Aktuelle Kardiologie 2017; 6(05): 367-372
DOI: 10.1055/s-0043-120291
Übersichtsarbeit
Georg Thieme Verlag KG Stuttgart · New York

Antithrombotische Therapie bei Vorhofflimmern und perkutaner Koronarintervention/akutem Koronarsyndrom

Antithrombotic Therapy in Patients with Atrial Fibrillation and Percutaneous Coronary Intervention/Acute Coronary Syndrome
Christoph B. Olivier
1   Stanford Center for Clinical Research (SCCR), Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
2   Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Germany
,
Christoph Bode
2   Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Germany
,
Martin Moser
2   Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Germany
› Author Affiliations
Further Information

Publication History

Publication Date:
13 November 2017 (online)

Zusammenfassung

Nach perkutaner Koronarintervention oder akutem Koronarsyndrom empfehlen die Leitlinien für Patienten mit Vorhofflimmern eine kombinierte antithrombotische Therapie. Diese reduziert das thrombotische Risiko, erhöht aber das Blutungsrisiko. Die klinische Herausforderung besteht darin, durch optimale antithrombotische Therapiestrategien das Risiko für thrombotische Ereignisse und Blutungen im bestmöglichen Verhältnis zu reduzieren. Dieser Übersichtsartikel hat das Ziel, die Evidenz zu verschiedenen Kombinationstherapien aufzuzeigen.

Abstract

Guidelines recommend a combined antithrombotic therapy for patients with atrial fibrillation undergoing percutaneous coronary intervention or presenting with acute coronary syndrome. Combined antithrombotic therapy reduces the thrombotic risk but increases the risk for bleeding. The challenge to clinicians is to identify the optimal balance between thrombotic and bleeding risk. This review aims to summarize the evidence on combined approaches.

 
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