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Aktuelle Neurologie 2018; 45(06): 445-456
DOI: 10.1055/s-0043-119541
Übersicht
© Georg Thieme Verlag KG Stuttgart · New York

Moderne Verfahren für die Strahlentherapie von Hirntumoren und Tumoren der Schädelbasis

Modern Techniques of Radiation Therapy in the Treatment of Brain Tumors and Tumors of the Skull Base
Christian D. Diehl
1   Klinik für Radioonkologie und Strahlentherapie, Technische Universität München (TUM), München
,
Stephanie E. Combs
1   Klinik für Radioonkologie und Strahlentherapie, Technische Universität München (TUM), München
2   Institut für Innovative Radiotherapie (iRT), Department of Radiation Sciences (DRS), Helmholtz Zentrum München, Oberschleißheim
› Author Affiliations
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Publication History

Publication Date:
04 April 2018 (online)

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Zusammenfassung

Die moderne Radioonkologie verfügt über eine Reihe hochmoderner Techniken, sodass die Therapiekonzepte und Entscheidungen individualisiert vorgenommen werden. Moderne Techniken ermöglichen eine hohe lokale Dosisdeposition bei optimaler Schonung von gesundem Normalgewebe. Diese Entwicklungen haben die therapeutische Breite der Strahlentherapie entscheidend verbessert. Molekulare Eigenschaften von Tumoren bestimmen heute die Therapieentscheidung im interdisziplinären Kontext sowohl für primäre als auch für sekundäre Hirntumoren. Vor allem Patienten mit Tumoren an der Schädelbasis profitieren von einer hochpräzisen Strahlentherapie, hier kann die Bestrahlung oft auch als Alternative zu Resektion gesehen werden.

Abstract

Today the choice of radiation oncology technique and treatment concept is highly individualized. Modern techniques enable high local dose depositions with significant sparing of normal tissue. This has significantly improved the therapeutic window. Molecular markers guide therapy decisions within the interdisciplinary context, for primary as well as secondary brain tumors. Skull base tumors profit from highly precise radiation techniques; often, radiotherapy can be seen as a treatment alternative to surgery in this region.

Schlüsselwörter

intensitätsmodulierte Strahlentherapie/IMRT - Stereotaxie - Gliome - Hirnmetastasen - Schädelbasistumore

Keywords

intensity modulated radiation therapy/IMRT - stereotaxy - gliomas - brain metastases - skull base tumors
 

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