Video Comment on Eui Joo Kim et al.

Eui Joo Kim et al. Safety and efficacy of glycopyrrolate as a premedication for endoscopic submucosal dissection: a randomized, double-blind, placebo-controlled study

In this randomized trial, it was found that glycopyrrolate before upper gastrointestinal endoscopic submucosal dissection (ESD) enhanced the ease of the procedure and significantly reduced secretion-related hypoxemia. This is one of the few studies demonstrating the efficacy of premedication in improving clinical outcomes for upper gastrointestinal ESD under deep sedation.