Folat und Folsäure

Zusammenfassung

Der Name „Folat“ stammt vom lateinischen Begriff „folium“ („Blatt“). Denn diese bioaktiven Verbindungen wurden erstmals aus Spinatblättern isoliert. Oft werden die Bezeichnungen Folat, Vitamin B₉ und Folsäure synonym gebraucht. Hierbei handelt es sich um wasserlösliche Verbindungen der Vitamin-B-Gruppe, zu der auch Folsäure und natürlich vorkommendes Folat zählen.

• Literatur

• 1 Food and Nutrition Board, I.o.M.. Folate. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B₆, Folate, Vitamin B₁₂, Pantothenic Acid, Biotin, and Choline. Washington, D.C.: National Academy Press; 1998
• 2 Choi SW, Mason JB. Folate and carcinogenesis: an integrated scheme. J Nutr 2000; 130: 129-132
• 3 Bailey LB, Gregory JF 3rd . Folate metabolism and requirements. J Nutr 1999; 129: 779-782
• 4 Gerhard GT, Duell PB. Homocysteine and atherosclerosis. Curr Opin Lipidol 1999; 10: 417-428
• 5 Jacques PF, Bostom AG, Wilson PW. et al. Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort. Am J Clin Nutr 2001; 73: 613-621
• 6 Verlinde PH, OeY I, Hendrickx ME. et al. L-ascorbic acid improves the serum folate response to an oral dose of [6S]-5-methyltetrahydrofolic acid in healthy men. Eur J Clin Nutr 2008; 62: 1224-1230
• 7 Whittaker P, Tufaro PR, Rader JI. Iron and folate in fortified cereals. J Am Coll Nutr 2001; 20: 247-254
• 8 Souci – Fachmann – Kraut Online Database. Verfügbar unter: http://www.sfk.online letzter Zugriff: 1. Mai 2017
• 9 Bailey LB. Dietary reference intakes for folate: the debut of dietary folate equivalents. Nutr Rev 1998; 56: 294-299
• 10 Scholl TO, Johnson WG. Folic acid: influence on the outcome of pregnancy. Am J Clin Nutr 2000; 71: 1295 S-1303 S
• 11 Obeid R, Oexle K, Rißmann A. et al. Folate status and health: challenges and opportunities. J Perinat Med 2016; 44: 261-268
• 12 de Bree A, van Dusseldorp M, Brouwer IA. et al. Folate intake in Europe: recommended, actual and desired intake. Eur J Clin Nutr 1997; 51: 643-660
• 13 SCF. ESCO Working Group. Opinion of Scientific Committee on Food on the tolerable upper intake level of folate. Brüssel: European Commission; 2000
• 14 McNulty H, Cuskelly GJ, Ward M. Response of red blood cell folate to intervention: implications for folate recommendations for the prevention of neural tube defects. Am J Clin Nutr 2000; 71: 1308 S-1311 S
• 15 Mills JL, Signore C. Neural tube defect rates before and after food fortification with folic acid. Birth Defects Res A Clin Mol Teratol 2004; 70: 844-845