Discovery of ACT-774312: A Potent and Selective CRTH2 Receptor Antagonist

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Synfacts 2023; 19(08): 0826
DOI: 10.1055/s-0042-1752722

Innovative Drug Discovery and Development

Contributor(s):

Antonia F. Stepan (Roche)

,

Thomas Puleo (Pfizer)

,

Danica A. Rankic (Pfizer)

ACT-774312 - plasma shift - CRTH2 receptor - allergic diseases - Fischer indole synthesis - isosteres - scaffold hop

Article published online:
14 July 2023

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany