CC BY 4.0 · Aorta (Stamford) 2022; 10(S 01): A1-A56
DOI: 10.1055/s-0042-1750987
Presentation Abstracts

Gender Related Outcomes in Asymptomatic Patients Undergoing Carotid Artery Stenting

Claudio Desantis
1   Department of Emergency and Organs Transplantation, Vascular and Endovascular Surgery Unit, “Aldo Moro” University of Bari School of Medicine, Bari, Italy, Bari, Italy
,
Sergio Zacà
1   Department of Emergency and Organs Transplantation, Vascular and Endovascular Surgery Unit, “Aldo Moro” University of Bari School of Medicine, Bari, Italy, Bari, Italy
,
Brunella Petrone
1   Department of Emergency and Organs Transplantation, Vascular and Endovascular Surgery Unit, “Aldo Moro” University of Bari School of Medicine, Bari, Italy, Bari, Italy
,
Domenico Angiletta
1   Department of Emergency and Organs Transplantation, Vascular and Endovascular Surgery Unit, “Aldo Moro” University of Bari School of Medicine, Bari, Italy, Bari, Italy
,
Raffaele Pulli
2   Vascular and Endovascular Surgery—University of Florence School of Medicine, Florence, Italy, Florence, Italy
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    Objective: Aim of the study was to evaluate the influence of gender in asymptomatic patients undergoing CAS.

    Methods: From January 2006 to December 2020, 438 consecutive patients with asymptomatic carotid artery stenosis > 70% underwent transfemoral CAS and were stratified in males (M) and females (F). Periprocedural 30-day outcomes were: stroke, death and myocardial infarction. Primary follow-up outcomes were: death and stroke rates. Secondary follow-up outcomes were: freedom from restenosis and reintervention rates. Follow-up data were analyzed at 1-, 5- and 10- years. Data were analyzed with Chi-square test and Fisher's exact test and follow-up outcomes with Kaplan-Meier curves. The log-rank test was used to determine differences between the groups and univariate analysis to identify the association between risk factors and intraoperative details with mortality and restenosis rates. p <0.05 was considered significant.

    Results: 462 procedures were performed (M, n = 321, 69.4%), 24 CAS were bilateral (5.5%). Mean age was 71.9±7.6 years (M, 72.1±7.8; F, 71.7±7.3). Periprocedural outcomes: stroke rate was 1.7% (n = 8: M, n = 5, 1.6%; F, n = 3, 2.1%; p = 0.462), mortality rate was 0.6% (n = 3, M group, p = 0.334), stroke/death rate was 2.3% (M: 8/11, p = 0.554), no cardiac events (MI) were recorded. Mean follow-up was 73.66 ± 40.83 months (M, 72.66; F, 76.01; p = 0.246). Overall survival rate was 96.1, 81.8 and 45.5% at 1-, 5- and 10 years respectively (p = 0.236). The overall stroke rate was 0.3, 0.9 and 4.3% (M, n = 6; F, n = 2; p = 0.774). Stroke-related mortality rate was 0.7 and 2.9% at 5- and 10-years (M, n = 4; F, n = 2; p = 0.763). Overall freedom from restenosis rate was 97.4, 93.4 and 89.5% (p = 0.322). Two severe restenosis (>80%, M) required a new endovascular intervention.

    Conclusion: Gender does not influence outcomes of CAS in asymptomatic patients at early and late follow-up.


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    No conflict of interest has been declared by the author(s).

    Publication History

    Article published online:
    10 June 2022

    © 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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